(40 nodes) (2021) Identification of Differentially Expressed Non-coding RNA Networks With Potential Immunoregulatory Roles During Salmonella Enteritidis Infection in Ducks. network (Anas platyrhynchos)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	TLR-15	TIR domain-containing protein. (863 aa)
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)
	SOCS3	Suppressor of cytokine signaling 3. (209 aa)
	FGL2	Fibrinogen like 2. (502 aa)
	TLR4	Toll like receptor 4. (843 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (141 aa)
	STAT1	Signal transducer and activator of transcription. (869 aa)
	HBEGF	Heparin binding EGF like growth factor. (378 aa)
	IL10	Interleukin 10. (177 aa)
	ZNF185	LIM zinc-binding domain-containing protein. (896 aa)
	NLRC5	NLR family CARD domain containing 5. (1891 aa)
	IL6	Uncharacterized protein. (350 aa)
	IL23R	Uncharacterized protein. (549 aa)
	NOTCH2	Notch receptor 2. (2425 aa)
	TOLLIP	Toll interacting protein. (310 aa)
	TGFBR3	Transforming growth factor beta receptor 3. (841 aa)
	TLR5	TIR domain-containing protein; Belongs to the Toll-like receptor family. (878 aa)
	CXCR4	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (338 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (731 aa)
	SPSB1	SplA/ryanodine receptor domain and SOCS box containing 1. (273 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (471 aa)
	RSAD2	Radical S-adenosyl methionine domain containing 2. (345 aa)
	SMAD3	Mothers against decapentaplegic homolog. (426 aa)
	MTOR	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
	STAT3	Signal transducer and activator of transcription. (942 aa)
	RASD1	Uncharacterized protein. (73 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (914 aa)
	MAP3K8	Mitogen-activated protein kinase kinase kinase 8. (487 aa)
	BAMBI	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
	IRF1	Interferon regulatory factor 1. (439 aa)
	THBS1	Thrombospondin 1. (1178 aa)
	IL22	Interleukin 22. (197 aa)
	CD74	CD74 molecule. (300 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit. (276 aa)
	IRF4	Interferon regulatory factor 4. (446 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (311 aa)
	FSHR	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (741 aa)
	CD9	Tetraspanin. (300 aa)
	GATA2	Uncharacterized protein. (93 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAMBI	SMAD3	ENSAPLP00000009181	ENSAPLP00000006649	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.540
CD36	CD9	ENSAPLP00000004116	ENSAPLP00000025554	CD36 molecule; Belongs to the CD36 family.	Tetraspanin.	0.626
CD36	IL10	ENSAPLP00000004116	ENSAPLP00000015242	CD36 molecule; Belongs to the CD36 family.	Interleukin 10.	0.446
CD36	IL6	ENSAPLP00000004116	ENSAPLP00000020478	CD36 molecule; Belongs to the CD36 family.	Uncharacterized protein.	0.542
CD36	INS	ENSAPLP00000004116	ENSAPLP00000012854	CD36 molecule; Belongs to the CD36 family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.610
CD36	THBS1	ENSAPLP00000004116	ENSAPLP00000022073	CD36 molecule; Belongs to the CD36 family.	Thrombospondin 1.	0.982
CD36	TLR-15	ENSAPLP00000004116	ENSAPLP00000009634	CD36 molecule; Belongs to the CD36 family.	TIR domain-containing protein.	0.476
CD36	TLR2	ENSAPLP00000004116	ENSAPLP00000011131	CD36 molecule; Belongs to the CD36 family.	Toll like receptor 2; Belongs to the Toll-like receptor family.	0.560
CD36	TLR4	ENSAPLP00000004116	ENSAPLP00000012401	CD36 molecule; Belongs to the CD36 family.	Toll like receptor 4.	0.862
CD74	CXCR4	ENSAPLP00000032611	ENSAPLP00000001302	CD74 molecule.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.693
CD9	CD36	ENSAPLP00000025554	ENSAPLP00000004116	Tetraspanin.	CD36 molecule; Belongs to the CD36 family.	0.626
CXCR4	CD74	ENSAPLP00000001302	ENSAPLP00000032611	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	CD74 molecule.	0.693
CXCR4	IL10	ENSAPLP00000001302	ENSAPLP00000015242	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Interleukin 10.	0.478
CXCR4	IL6	ENSAPLP00000001302	ENSAPLP00000020478	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.692
CXCR4	STAT3	ENSAPLP00000001302	ENSAPLP00000007496	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Signal transducer and activator of transcription.	0.488
CXCR4	TLR4	ENSAPLP00000001302	ENSAPLP00000012401	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Toll like receptor 4.	0.447
FGL2	TGFBR3	ENSAPLP00000011892	ENSAPLP00000022012	Fibrinogen like 2.	Transforming growth factor beta receptor 3.	0.402
FGL2	ZNF185	ENSAPLP00000011892	ENSAPLP00000017927	Fibrinogen like 2.	LIM zinc-binding domain-containing protein.	0.543
GATA2	JUN	ENSAPLP00000024003	ENSAPLP00000031204	Uncharacterized protein.	Jun proto-oncogene, AP-1 transcription factor subunit.	0.505
HBEGF	RASD1	ENSAPLP00000015122	ENSAPLP00000008375	Heparin binding EGF like growth factor.	Uncharacterized protein.	0.440