(13 nodes) (2021) The Role of B Cells in Adult and Paediatric Liver Injury. network (Anas platyrhynchos)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	CD86	CD86 molecule. (341 aa)
	ENO1	Enolase_N domain-containing protein. (172 aa)
	IL6	Uncharacterized protein. (350 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	CD4	Ig-like domain-containing protein. (264 aa)
	IL10	Interleukin 10. (177 aa)
	AICDA	Activation induced cytidine deaminase. (203 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
	TLR4	Toll like receptor 4. (843 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	IL21	Interleukin; Belongs to the IL-15/IL-21 family. (145 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)
	BCR	BCR activator of RhoGEF and GTPase. (1280 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AICDA	BCL2	ENSAPLP00000013772	ENSAPLP00000019939	Activation induced cytidine deaminase.	BCL2 apoptosis regulator.	0.415
AICDA	CD4	ENSAPLP00000013772	ENSAPLP00000018005	Activation induced cytidine deaminase.	Ig-like domain-containing protein.	0.514
AICDA	CD86	ENSAPLP00000013772	ENSAPLP00000026026	Activation induced cytidine deaminase.	CD86 molecule.	0.411
AICDA	TLR7	ENSAPLP00000013772	ENSAPLP00000003630	Activation induced cytidine deaminase.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.445
BCL2	AICDA	ENSAPLP00000019939	ENSAPLP00000013772	BCL2 apoptosis regulator.	Activation induced cytidine deaminase.	0.415
BCL2	CD4	ENSAPLP00000019939	ENSAPLP00000018005	BCL2 apoptosis regulator.	Ig-like domain-containing protein.	0.763
BCL2	IFNG	ENSAPLP00000019939	ENSAPLP00000012661	BCL2 apoptosis regulator.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.545
BCL2	IL10	ENSAPLP00000019939	ENSAPLP00000015242	BCL2 apoptosis regulator.	Interleukin 10.	0.670
BCL2	IL6	ENSAPLP00000019939	ENSAPLP00000020478	BCL2 apoptosis regulator.	Uncharacterized protein.	0.782
BCL2	TLR4	ENSAPLP00000019939	ENSAPLP00000012401	BCL2 apoptosis regulator.	Toll like receptor 4.	0.606
CD4	AICDA	ENSAPLP00000018005	ENSAPLP00000013772	Ig-like domain-containing protein.	Activation induced cytidine deaminase.	0.514
CD4	BCL2	ENSAPLP00000018005	ENSAPLP00000019939	Ig-like domain-containing protein.	BCL2 apoptosis regulator.	0.763
CD4	CD86	ENSAPLP00000018005	ENSAPLP00000026026	Ig-like domain-containing protein.	CD86 molecule.	0.966
CD4	IFNG	ENSAPLP00000018005	ENSAPLP00000012661	Ig-like domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.958
CD4	IL10	ENSAPLP00000018005	ENSAPLP00000015242	Ig-like domain-containing protein.	Interleukin 10.	0.959
CD4	IL21	ENSAPLP00000018005	ENSAPLP00000006533	Ig-like domain-containing protein.	Interleukin; Belongs to the IL-15/IL-21 family.	0.764
CD4	IL6	ENSAPLP00000018005	ENSAPLP00000020478	Ig-like domain-containing protein.	Uncharacterized protein.	0.961
CD4	TLR4	ENSAPLP00000018005	ENSAPLP00000012401	Ig-like domain-containing protein.	Toll like receptor 4.	0.837
CD4	TLR7	ENSAPLP00000018005	ENSAPLP00000003630	Ig-like domain-containing protein.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.873
CD86	AICDA	ENSAPLP00000026026	ENSAPLP00000013772	CD86 molecule.	Activation induced cytidine deaminase.	0.411