STRINGSTRING
IRS4 IRS4 CCK CCK CALR CALR IRS2 IRS2 JAK2 JAK2 POMC POMC ADIPOR2 ADIPOR2 CALR3 CALR3 STAT3 STAT3 AGRP AGRP FOXO1 FOXO1 PLCB2 PLCB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IRS4Insulin receptor substrate 4. (1128 aa)
CCKCholecystokinin. (130 aa)
CALRCalreticulin. (531 aa)
IRS2Insulin receptor substrate 2. (1161 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
POMCProopiomelanocortin. (234 aa)
ADIPOR2Adiponectin receptor 2. (428 aa)
CALR3Calreticulin. (389 aa)
STAT3Signal transducer and activator of transcription. (942 aa)
AGRPAgouti domain-containing protein. (130 aa)
FOXO1Forkhead box O1. (678 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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