36 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PCK1	Phosphoenolpyruvate carboxykinase 1. (622 aa)
	G6PC	Glucose-6-phosphatase catalytic subunit. (358 aa)
	PPARGC1A	PPARG coactivator 1 alpha. (834 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit. (276 aa)
	LECT2	Leukocyte cell derived chemotaxin 2. (151 aa)
	GPATCH11	G-patch domain containing 11. (256 aa)
	IL-17	Uncharacterized protein. (191 aa)
	BRCA1	BRCA1 DNA repair associated. (1846 aa)
	FOSB	FosB proto-oncogene, AP-1 transcription factor subunit. (223 aa)
	BMP15	Bone morphogenetic protein 15. (356 aa)
	CEP128	Centrosomal protein 128. (1099 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (369 aa)
	ANGPTL4	Angiopoietin like 4. (344 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (816 aa)
	BAG3	WW domain-containing protein. (183 aa)
	TCEA3	Transcription elongation factor A3. (646 aa)
	UBE2T	Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (373 aa)
	PDK4	Protein-serine/threonine kinase. (422 aa)
	SLC24A1	Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (664 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (141 aa)
	FN3KRP	Fructosamine 3 kinase related protein; Belongs to the fructosamine kinase family. (309 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
	FOSL2	FOS like 2, AP-1 transcription factor subunit. (323 aa)
	ETNPPL	Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (505 aa)
	AR	Androgen receptor. (385 aa)
	IL18	Interleukin-18. (197 aa)
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
	CCNA2	Cyclin A2; Belongs to the cyclin family. (390 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (548 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
	RAB3B	RAB3B, member RAS oncogene family. (219 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)
	BAG2	BCL2 associated athanogene 2. (225 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (652 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	HSP90B1	ENSAPLP00000000524	ENSAPLP00000019318	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Heat shock protein 90 beta family member 1.	0.414
ANGPTL4	PCK1	ENSAPLP00000021456	ENSAPLP00000002378	Angiopoietin like 4.	Phosphoenolpyruvate carboxykinase 1.	0.456
AR	BRCA1	ENSAPLP00000006185	ENSAPLP00000026654	Androgen receptor.	BRCA1 DNA repair associated.	0.492
AR	ESR1	ENSAPLP00000006185	ENSAPLP00000004132	Androgen receptor.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.640
AR	JUN	ENSAPLP00000006185	ENSAPLP00000031204	Androgen receptor.	Jun proto-oncogene, AP-1 transcription factor subunit.	0.426
BAG2	BAG3	ENSAPLP00000003189	ENSAPLP00000018696	BCL2 associated athanogene 2.	WW domain-containing protein.	0.869
BAG2	HSPA5	ENSAPLP00000003189	ENSAPLP00000002711	BCL2 associated athanogene 2.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.705
BAG2	UBE2T	ENSAPLP00000003189	ENSAPLP00000016169	BCL2 associated athanogene 2.	Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.	0.554
BAG3	BAG2	ENSAPLP00000018696	ENSAPLP00000003189	WW domain-containing protein.	BCL2 associated athanogene 2.	0.869
BAG3	HSP90B1	ENSAPLP00000018696	ENSAPLP00000019318	WW domain-containing protein.	Heat shock protein 90 beta family member 1.	0.684
BAG3	HSPA5	ENSAPLP00000018696	ENSAPLP00000002711	WW domain-containing protein.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.940
BAG3	UBE2T	ENSAPLP00000018696	ENSAPLP00000016169	WW domain-containing protein.	Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.	0.552
BRCA1	AR	ENSAPLP00000026654	ENSAPLP00000006185	BRCA1 DNA repair associated.	Androgen receptor.	0.492
BRCA1	CCNA2	ENSAPLP00000026654	ENSAPLP00000004742	BRCA1 DNA repair associated.	Cyclin A2; Belongs to the cyclin family.	0.652
BRCA1	CDK1	ENSAPLP00000026654	ENSAPLP00000010015	BRCA1 DNA repair associated.	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.	0.763
BRCA1	ESR1	ENSAPLP00000026654	ENSAPLP00000004132	BRCA1 DNA repair associated.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.920
BRCA1	JUN	ENSAPLP00000026654	ENSAPLP00000031204	BRCA1 DNA repair associated.	Jun proto-oncogene, AP-1 transcription factor subunit.	0.430
BRCA1	UBE2T	ENSAPLP00000026654	ENSAPLP00000016169	BRCA1 DNA repair associated.	Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.	0.773
CCNA2	BRCA1	ENSAPLP00000004742	ENSAPLP00000026654	Cyclin A2; Belongs to the cyclin family.	BRCA1 DNA repair associated.	0.652
CCNA2	CDK1	ENSAPLP00000004742	ENSAPLP00000010015	Cyclin A2; Belongs to the cyclin family.	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.	0.999