(14 nodes) (2022) From bats to pangolins: new insights into species differences in the structure and function of the immune system. network (Anas platyrhynchos)

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second shell of interactors

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Your Input:
	IRF7	Interferon regulatory factor 7. (523 aa)
	SOCS1	Suppressor of cytokine signaling 1. (207 aa)
	MAVS	CARD_2 domain-containing protein. (619 aa)
	USP18	USP domain-containing protein; Belongs to the peptidase C19 family. (414 aa)
	IFNAR1	Interferon alpha and beta receptor subunit 1. (584 aa)
	TLR4	Toll like receptor 4. (843 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
	U3J1K3_ANAPP	Uncharacterized protein; Belongs to the peptidase C14A family. (284 aa)
	ACE2	Angiotensin-converting enzyme. (653 aa)
	MX1	MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (721 aa)
	IL6	Uncharacterized protein. (350 aa)
	ENSAPLP00000028410	Uncharacterized protein. (157 aa)
	CIITA	NACHT domain-containing protein. (1109 aa)
	RNASEL	Uncharacterized protein. (772 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	IFNG	ENSAPLP00000014389	ENSAPLP00000012661	Angiotensin-converting enzyme.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.427
ACE2	IL6	ENSAPLP00000014389	ENSAPLP00000020478	Angiotensin-converting enzyme.	Uncharacterized protein.	0.815
CIITA	MAVS	ENSAPLP00000028971	ENSAPLP00000002790	NACHT domain-containing protein.	CARD_2 domain-containing protein.	0.502
ENSAPLP00000028410	IFNAR1	ENSAPLP00000028410	ENSAPLP00000011065	Uncharacterized protein.	Interferon alpha and beta receptor subunit 1.	0.971
ENSAPLP00000028410	IFNG	ENSAPLP00000028410	ENSAPLP00000012661	Uncharacterized protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.970
ENSAPLP00000028410	IL6	ENSAPLP00000028410	ENSAPLP00000020478	Uncharacterized protein.	Uncharacterized protein.	0.807
ENSAPLP00000028410	IRF7	ENSAPLP00000028410	ENSAPLP00000026565	Uncharacterized protein.	Interferon regulatory factor 7.	0.961
ENSAPLP00000028410	MAVS	ENSAPLP00000028410	ENSAPLP00000002790	Uncharacterized protein.	CARD_2 domain-containing protein.	0.632
ENSAPLP00000028410	MX1	ENSAPLP00000028410	ENSAPLP00000015901	Uncharacterized protein.	MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.622
ENSAPLP00000028410	SOCS1	ENSAPLP00000028410	ENSAPLP00000000236	Uncharacterized protein.	Suppressor of cytokine signaling 1.	0.455
ENSAPLP00000028410	TLR4	ENSAPLP00000028410	ENSAPLP00000012401	Uncharacterized protein.	Toll like receptor 4.	0.519
ENSAPLP00000028410	U3J1K3_ANAPP	ENSAPLP00000028410	ENSAPLP00000013380	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.440
IFNAR1	ENSAPLP00000028410	ENSAPLP00000011065	ENSAPLP00000028410	Interferon alpha and beta receptor subunit 1.	Uncharacterized protein.	0.971
IFNAR1	IFNG	ENSAPLP00000011065	ENSAPLP00000012661	Interferon alpha and beta receptor subunit 1.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.961
IFNAR1	IL6	ENSAPLP00000011065	ENSAPLP00000020478	Interferon alpha and beta receptor subunit 1.	Uncharacterized protein.	0.490
IFNAR1	IRF7	ENSAPLP00000011065	ENSAPLP00000026565	Interferon alpha and beta receptor subunit 1.	Interferon regulatory factor 7.	0.617
IFNAR1	MAVS	ENSAPLP00000011065	ENSAPLP00000002790	Interferon alpha and beta receptor subunit 1.	CARD_2 domain-containing protein.	0.553
IFNAR1	MX1	ENSAPLP00000011065	ENSAPLP00000015901	Interferon alpha and beta receptor subunit 1.	MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.548
IFNAR1	RNASEL	ENSAPLP00000011065	ENSAPLP00000029801	Interferon alpha and beta receptor subunit 1.	Uncharacterized protein.	0.562
IFNAR1	SOCS1	ENSAPLP00000011065	ENSAPLP00000000236	Interferon alpha and beta receptor subunit 1.	Suppressor of cytokine signaling 1.	0.858