(4 nodes) (2022) Case Report: Invasive Cryptococcosis in French Guiana: Immune and Genetic Investigation in Six Non-HIV Patients. network (Anas platyrhynchos)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	STAT3	Signal transducer and activator of transcription. (942 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
	STAT1	Signal transducer and activator of transcription. (869 aa)
	CD4	Ig-like domain-containing protein. (264 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	IFNG	ENSAPLP00000018005	ENSAPLP00000012661	Ig-like domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.958
CD4	STAT1	ENSAPLP00000018005	ENSAPLP00000013135	Ig-like domain-containing protein.	Signal transducer and activator of transcription.	0.806
CD4	STAT3	ENSAPLP00000018005	ENSAPLP00000007496	Ig-like domain-containing protein.	Signal transducer and activator of transcription.	0.800
IFNG	CD4	ENSAPLP00000012661	ENSAPLP00000018005	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Ig-like domain-containing protein.	0.958
IFNG	STAT1	ENSAPLP00000012661	ENSAPLP00000013135	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Signal transducer and activator of transcription.	0.890
IFNG	STAT3	ENSAPLP00000012661	ENSAPLP00000007496	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Signal transducer and activator of transcription.	0.805
STAT1	CD4	ENSAPLP00000013135	ENSAPLP00000018005	Signal transducer and activator of transcription.	Ig-like domain-containing protein.	0.806
STAT1	IFNG	ENSAPLP00000013135	ENSAPLP00000012661	Signal transducer and activator of transcription.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.890
STAT1	STAT3	ENSAPLP00000013135	ENSAPLP00000007496	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.961
STAT3	CD4	ENSAPLP00000007496	ENSAPLP00000018005	Signal transducer and activator of transcription.	Ig-like domain-containing protein.	0.800
STAT3	IFNG	ENSAPLP00000007496	ENSAPLP00000012661	Signal transducer and activator of transcription.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.805
STAT3	STAT1	ENSAPLP00000007496	ENSAPLP00000013135	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.961