(11 nodes) (2022) Analysis of miRNA Expression Profiling of RIP2 Knockdown in Chicken HD11 Cells When Infected with Avian Pathogenic E. coli (APEC). network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PXDN	Peroxidasin. (1193 aa)
	ENSAPLP00000029472	Uncharacterized protein. (1406 aa)
	SHISA2	Shisa family member 2. (287 aa)
	IL6	Uncharacterized protein. (350 aa)
	IRF2	Interferon regulatory factor 2. (433 aa)
	RGS2	Regulator of G protein signaling 2. (212 aa)
	IRF1	Interferon regulatory factor 1. (439 aa)
	SOCS3	Suppressor of cytokine signaling 3. (209 aa)
	TMEFF2	Transmembrane protein with EGF like and two follistatin like domains 2. (334 aa)
	ULK1	Unc-51 like autophagy activating kinase 1. (753 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (556 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000029472	IL6	ENSAPLP00000029472	ENSAPLP00000020478	Uncharacterized protein.	Uncharacterized protein.	0.758
ENSAPLP00000029472	PXDN	ENSAPLP00000029472	ENSAPLP00000015658	Uncharacterized protein.	Peroxidasin.	0.616
IL6	ENSAPLP00000029472	ENSAPLP00000020478	ENSAPLP00000029472	Uncharacterized protein.	Uncharacterized protein.	0.758
IL6	IRF1	ENSAPLP00000020478	ENSAPLP00000009421	Uncharacterized protein.	Interferon regulatory factor 1.	0.672
IL6	PXDN	ENSAPLP00000020478	ENSAPLP00000015658	Uncharacterized protein.	Peroxidasin.	0.758
IL6	SOCS3	ENSAPLP00000020478	ENSAPLP00000011852	Uncharacterized protein.	Suppressor of cytokine signaling 3.	0.856
IRF1	IL6	ENSAPLP00000009421	ENSAPLP00000020478	Interferon regulatory factor 1.	Uncharacterized protein.	0.672
IRF1	IRF2	ENSAPLP00000009421	ENSAPLP00000017376	Interferon regulatory factor 1.	Interferon regulatory factor 2.	0.753
IRF1	SOCS3	ENSAPLP00000009421	ENSAPLP00000011852	Interferon regulatory factor 1.	Suppressor of cytokine signaling 3.	0.722
IRF2	IRF1	ENSAPLP00000017376	ENSAPLP00000009421	Interferon regulatory factor 2.	Interferon regulatory factor 1.	0.753
PXDN	ENSAPLP00000029472	ENSAPLP00000015658	ENSAPLP00000029472	Peroxidasin.	Uncharacterized protein.	0.616
PXDN	IL6	ENSAPLP00000015658	ENSAPLP00000020478	Peroxidasin.	Uncharacterized protein.	0.758
SOCS3	IL6	ENSAPLP00000011852	ENSAPLP00000020478	Suppressor of cytokine signaling 3.	Uncharacterized protein.	0.856
SOCS3	IRF1	ENSAPLP00000011852	ENSAPLP00000009421	Suppressor of cytokine signaling 3.	Interferon regulatory factor 1.	0.722