STRINGSTRING
TMPRSS2 TMPRSS2 CGAS CGAS IL6 IL6 NOD1 NOD1 MYD88 MYD88 ENSAPLP00000028410 ENSAPLP00000028410 RNASEL RNASEL IRF7 IRF7 DDX3X DDX3X TRAF6 TRAF6 MAVS MAVS ACE ACE SYK SYK TLR7 TLR7 IL18 IL18 TBK1 TBK1 TLR3 TLR3 IRF1 IRF1 CASP6 CASP6 IFNAR1 IFNAR1 IL4 IL4 U3J1K3_ANAPP U3J1K3_ANAPP ACE2 ACE2 CASP8 CASP8 GSDME GSDME CASP3 CASP3 U3J6D9_ANAPP U3J6D9_ANAPP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (485 aa)
CGASCyclic GMP-AMP synthase. (545 aa)
IL6Uncharacterized protein. (350 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (951 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (311 aa)
ENSAPLP00000028410Uncharacterized protein. (157 aa)
RNASELUncharacterized protein. (772 aa)
IRF7Interferon regulatory factor 7. (523 aa)
DDX3XUncharacterized protein; Belongs to the DEAD box helicase family. (677 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
MAVSCARD_2 domain-containing protein. (619 aa)
ACEAngiotensin-converting enzyme. (1406 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)
IL18Interleukin-18. (197 aa)
TBK1TANK binding kinase 1. (600 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (914 aa)
IRF1Interferon regulatory factor 1. (439 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (295 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (584 aa)
IL4Uncharacterized protein. (136 aa)
U3J1K3_ANAPPUncharacterized protein; Belongs to the peptidase C14A family. (284 aa)
ACE2Angiotensin-converting enzyme. (653 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (466 aa)
GSDMEGasdermin E. (499 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (306 aa)
U3J6D9_ANAPPUncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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