30 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	SOAT1	O-acyltransferase. (548 aa)
	MAP3K2	Mitogen-activated protein kinase kinase kinase 2. (624 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	PITX2	Homeobox protein. (334 aa)
	TYR	Tyrosinase. (490 aa)
	RPL8	Ribosomal protein L8. (257 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2699 aa)
	PXDN	Peroxidasin. (1193 aa)
	PLD4	Phospholipase D family member 4. (481 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1347 aa)
	TYRP1	Tyrosinase related protein 1. (529 aa)
	GPX2	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (141 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	WNT16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	ABCA7	ABC transporter domain-containing protein. (266 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1136 aa)
	FZD6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (890 aa)
	ENSAPLP00000029472	Uncharacterized protein. (1406 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (306 aa)
	MC1R	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (314 aa)
	FZD7	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (573 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (656 aa)
	FZD1	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (556 aa)
	LRP2	LDL receptor related protein 2. (4583 aa)
	LIPG	Lipase G, endothelial type. (505 aa)
	TSPO	Translocator protein. (166 aa)
	APOB	Apolipoprotein B. (4563 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOB	LRP2	ENSAPLP00000011529	ENSAPLP00000007313	Apolipoprotein B.	LDL receptor related protein 2.	0.746
APOB	PCSK9	ENSAPLP00000011529	ENSAPLP00000004259	Apolipoprotein B.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.694
APOB	TERT	ENSAPLP00000011529	ENSAPLP00000017788	Apolipoprotein B.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.586
APOB	WNT5A	ENSAPLP00000011529	ENSAPLP00000011950	Apolipoprotein B.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.413
BCL2	CASP3	ENSAPLP00000019939	ENSAPLP00000015062	BCL2 apoptosis regulator.	Caspase 3; Belongs to the peptidase C14A family.	0.967
BCL2	ENSAPLP00000029472	ENSAPLP00000019939	ENSAPLP00000029472	BCL2 apoptosis regulator.	Uncharacterized protein.	0.700
BCL2	GPX2	ENSAPLP00000019939	ENSAPLP00000018867	BCL2 apoptosis regulator.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.470
BCL2	PXDN	ENSAPLP00000019939	ENSAPLP00000015658	BCL2 apoptosis regulator.	Peroxidasin.	0.700
BCL2	TERT	ENSAPLP00000019939	ENSAPLP00000017788	BCL2 apoptosis regulator.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.430
CASP3	BCL2	ENSAPLP00000015062	ENSAPLP00000019939	Caspase 3; Belongs to the peptidase C14A family.	BCL2 apoptosis regulator.	0.967
CASP3	ENSAPLP00000029472	ENSAPLP00000015062	ENSAPLP00000029472	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.766
CASP3	GPX2	ENSAPLP00000015062	ENSAPLP00000018867	Caspase 3; Belongs to the peptidase C14A family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.452
CASP3	PXDN	ENSAPLP00000015062	ENSAPLP00000015658	Caspase 3; Belongs to the peptidase C14A family.	Peroxidasin.	0.766
ENSAPLP00000029472	BCL2	ENSAPLP00000029472	ENSAPLP00000019939	Uncharacterized protein.	BCL2 apoptosis regulator.	0.700
ENSAPLP00000029472	CASP3	ENSAPLP00000029472	ENSAPLP00000015062	Uncharacterized protein.	Caspase 3; Belongs to the peptidase C14A family.	0.766
ENSAPLP00000029472	PXDN	ENSAPLP00000029472	ENSAPLP00000015658	Uncharacterized protein.	Peroxidasin.	0.616
FZD1	FZD6	ENSAPLP00000006131	ENSAPLP00000028956	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.426
FZD1	WNT16	ENSAPLP00000006131	ENSAPLP00000024983	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.878
FZD1	WNT4	ENSAPLP00000006131	ENSAPLP00000017090	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.918
FZD1	WNT5A	ENSAPLP00000006131	ENSAPLP00000011950	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.990