(42 nodes) (2023) L-Theanine and Immunity: A Review. network (Anas platyrhynchos)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	NOS1	Nitric oxide synthase; Produces nitric oxide (NO). (1420 aa)
	U3ITT3_ANAPP	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	GPT2	Glutamic--pyruvic transaminase 2. (423 aa)
	CCN2	Cellular communication network factor 2. (347 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (446 aa)
	STAT3	Signal transducer and activator of transcription. (942 aa)
	MMP13	Matrix metallopeptidase 13. (472 aa)
	MTOR	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
	GOT2	Aspartate aminotransferase. (440 aa)
	IL-2	Interleukin; Belongs to the IL-15/IL-21 family. (140 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	U3I3U9_ANAPP	Uncharacterized protein. (346 aa)
	ENDOG	Endonuclease. (303 aa)
	PDCD4	Programmed cell death 4. (467 aa)
	EGFR	Receptor protein-tyrosine kinase. (1219 aa)
	ENSAPLP00000030826	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (121 aa)
	JAK2	Tyrosine-protein kinase. (1130 aa)
	CNR1	Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (594 aa)
	CD86	CD86 molecule. (341 aa)
	CD83	CD83 molecule. (218 aa)
	GLUL	Glutamine synthetase. (561 aa)
	CKB	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
	GOT1	Aspartate aminotransferase. (403 aa)
	IL6	Uncharacterized protein. (350 aa)
	CD4	Ig-like domain-containing protein. (264 aa)
	CD44	CD44 molecule (Indian blood group). (645 aa)
	CD40	TNFR-Cys domain-containing protein. (214 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1151 aa)
	IL10	Interleukin 10. (177 aa)
	MAPKAPK2	MAPK activated protein kinase 2. (397 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (306 aa)
	U3J3R3_ANAPP	Glutamine synthetase. (374 aa)
	CLDN3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (214 aa)
	RAP1A	Uncharacterized protein. (184 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	TLR4	Toll like receptor 4. (843 aa)
	IL17RA	Interleukin 17 receptor A. (850 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1182 aa)
	IL4	Uncharacterized protein. (136 aa)
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP3	CASP9	ENSAPLP00000015062	ENSAPLP00000008534	Caspase 3; Belongs to the peptidase C14A family.	Caspase 9; Belongs to the peptidase C14A family.	0.857
CASP3	CD4	ENSAPLP00000015062	ENSAPLP00000018005	Caspase 3; Belongs to the peptidase C14A family.	Ig-like domain-containing protein.	0.666
CASP3	CD44	ENSAPLP00000015062	ENSAPLP00000016839	Caspase 3; Belongs to the peptidase C14A family.	CD44 molecule (Indian blood group).	0.586
CASP3	EGF	ENSAPLP00000015062	ENSAPLP00000011666	Caspase 3; Belongs to the peptidase C14A family.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.611
CASP3	EGFR	ENSAPLP00000015062	ENSAPLP00000002564	Caspase 3; Belongs to the peptidase C14A family.	Receptor protein-tyrosine kinase.	0.480
CASP3	ENDOG	ENSAPLP00000015062	ENSAPLP00000004487	Caspase 3; Belongs to the peptidase C14A family.	Endonuclease.	0.524
CASP3	ENSAPLP00000030826	ENSAPLP00000015062	ENSAPLP00000030826	Caspase 3; Belongs to the peptidase C14A family.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.937
CASP3	IL10	ENSAPLP00000015062	ENSAPLP00000015242	Caspase 3; Belongs to the peptidase C14A family.	Interleukin 10.	0.720
CASP3	IL4	ENSAPLP00000015062	ENSAPLP00000011598	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.485
CASP3	IL6	ENSAPLP00000015062	ENSAPLP00000020478	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.788
CASP3	STAT3	ENSAPLP00000015062	ENSAPLP00000007496	Caspase 3; Belongs to the peptidase C14A family.	Signal transducer and activator of transcription.	0.721
CASP3	TLR4	ENSAPLP00000015062	ENSAPLP00000012401	Caspase 3; Belongs to the peptidase C14A family.	Toll like receptor 4.	0.688
CASP3	U3ITT3_ANAPP	ENSAPLP00000015062	ENSAPLP00000010656	Caspase 3; Belongs to the peptidase C14A family.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.937
CASP9	CASP3	ENSAPLP00000008534	ENSAPLP00000015062	Caspase 9; Belongs to the peptidase C14A family.	Caspase 3; Belongs to the peptidase C14A family.	0.857
CASP9	ENDOG	ENSAPLP00000008534	ENSAPLP00000004487	Caspase 9; Belongs to the peptidase C14A family.	Endonuclease.	0.502
CASP9	ENSAPLP00000030826	ENSAPLP00000008534	ENSAPLP00000030826	Caspase 9; Belongs to the peptidase C14A family.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.998
CASP9	IL6	ENSAPLP00000008534	ENSAPLP00000020478	Caspase 9; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.588
CASP9	STAT3	ENSAPLP00000008534	ENSAPLP00000007496	Caspase 9; Belongs to the peptidase C14A family.	Signal transducer and activator of transcription.	0.491
CASP9	TLR4	ENSAPLP00000008534	ENSAPLP00000012401	Caspase 9; Belongs to the peptidase C14A family.	Toll like receptor 4.	0.473
CASP9	U3ITT3_ANAPP	ENSAPLP00000008534	ENSAPLP00000010656	Caspase 9; Belongs to the peptidase C14A family.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.998