STRINGSTRING
SOCS1 SOCS1 UBE2O UBE2O ANAPC2 ANAPC2 WWP1 WWP1 PIAS1 PIAS1 HERC1 HERC1 UBE2J2 UBE2J2 ANAPC5 ANAPC5 HERC2 HERC2 UBE2R2 UBE2R2 STUB1 STUB1 UBR5 UBR5 UBE2F UBE2F NEDD4 NEDD4 ANAPC7 ANAPC7 UBE2L3 UBE2L3 UBE2W UBE2W PPIL2 PPIL2 RPS27A RPS27A BIRC2 BIRC2 ANAPC13 ANAPC13 UBE2E2 UBE2E2 UBE3C UBE3C DDB1 DDB1 BTRC BTRC FBXO2 FBXO2 UBA6 UBA6 ERCC8 ERCC8 FBXW11 FBXW11 CDC20 CDC20 U3ISA1_ANAPP U3ISA1_ANAPP RBX1 RBX1 RHOBTB1 RHOBTB1 PIAS4 PIAS4 MDM2 MDM2 UBA2 UBA2 UBE2E3 UBE2E3 CBLB CBLB FBXW8 FBXW8 SOCS3 SOCS3 CDC16 CDC16 ANAPC1 ANAPC1 UBA3 UBA3 ITCH ITCH CBL CBL UBE3A UBE3A UBE2B UBE2B CUL5 CUL5 SKP1 SKP1 UBE2J1 UBE2J1 UBE2I UBE2I FANCL FANCL BIRC7 BIRC7 ENSAPLP00000017612 ENSAPLP00000017612 SKP2 SKP2 CUL2 CUL2 NHLRC1 NHLRC1 UBE2D1 UBE2D1 UBE2G2 UBE2G2 PRPF19 PRPF19 COP1 COP1 CUL4B CUL4B UBE2G1 UBE2G1 CUL1 CUL1 CUL4A CUL4A SIAH1 SIAH1 ENSAPLP00000023897 ENSAPLP00000023897 CDC27 CDC27 RRP8 RRP8 MAP3K1 MAP3K1 SMURF1 SMURF1 MID1 MID1 XIAP XIAP FBXW7 FBXW7 FBXO4 FBXO4 PRKN PRKN HERC4 HERC4 BRCA1 BRCA1 TRIM37 TRIM37 FZR1 FZR1 UBE2A UBE2A UBE2C UBE2C TRIM32 TRIM32 TRAF6 TRAF6 UBE4A UBE4A ELOC ELOC NEDD4L NEDD4L ANAPC10 ANAPC10 KLHL13 KLHL13 ENSAPLP00000030796 ENSAPLP00000030796 DET1 DET1 UBE2D3 UBE2D3 CDC23 CDC23 UBE2H-2 UBE2H-2 TRIP12 TRIP12 CUL3 CUL3 UBA7 UBA7 UBOX5 UBOX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS1Suppressor of cytokine signaling 1. (207 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1339 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (811 aa)
WWP1E3 ubiquitin-protein ligase. (925 aa)
PIAS1Uncharacterized protein. (577 aa)
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4860 aa)
UBE2J2Ubiquitin conjugating enzyme E2 J2. (259 aa)
ANAPC5Anaphase promoting complex subunit 5. (744 aa)
HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4828 aa)
UBE2R2Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
STUB1STIP1 homology and U-box containing protein 1. (330 aa)
UBR5UBR-type domain-containing protein. (1953 aa)
UBE2FUBIQUITIN_CONJUGAT_2 domain-containing protein. (89 aa)
NEDD4E3 ubiquitin-protein ligase. (875 aa)
ANAPC7Anaphase promoting complex subunit 7. (513 aa)
UBE2L3Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
UBE2WUBIQUITIN_CONJUGAT_2 domain-containing protein. (158 aa)
PPIL2Peptidylprolyl isomerase like 2. (483 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
BIRC2Uncharacterized protein. (611 aa)
ANAPC13Uncharacterized protein. (74 aa)
UBE2E2Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
UBE3CUbiquitin protein ligase E3C. (1084 aa)
DDB1Damage specific DNA binding protein 1. (1050 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (608 aa)
FBXO2F-box protein 2. (292 aa)
UBA6Ubiquitin like modifier activating enzyme 6. (1021 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (458 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
CDC20Cell division cycle 20. (505 aa)
U3ISA1_ANAPPHECT domain-containing protein. (1028 aa)
RBX1Ring-box 1. (108 aa)
RHOBTB1Uncharacterized protein. (575 aa)
PIAS4Protein inhibitor of activated STAT 4. (485 aa)
MDM2Uncharacterized protein. (423 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (541 aa)
UBE2E3Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
CBLBCbl proto-oncogene B. (971 aa)
FBXW8F-box and WD repeat domain containing 8. (436 aa)
SOCS3Suppressor of cytokine signaling 3. (209 aa)
CDC16Cell division cycle 16. (623 aa)
ANAPC1Anaphase promoting complex subunit 1. (1910 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (442 aa)
ITCHE3 ubiquitin-protein ligase. (769 aa)
CBLCbl proto-oncogene. (814 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (880 aa)
UBE2BUbiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (268 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
FANCLFA complementation group L. (373 aa)
BIRC7Baculoviral IAP repeat containing 7. (440 aa)
ENSAPLP00000017612UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (124 aa)
SKP2S-phase kinase associated protein 2. (671 aa)
CUL2Cullin 2; Belongs to the cullin family. (774 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (377 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1. (97 aa)
UBE2G2UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (137 aa)
PRPF19Pre-mRNA processing factor 19. (191 aa)
COP1COP1 E3 ubiquitin ligase. (642 aa)
CUL4BCullin 4B; Belongs to the cullin family. (886 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (266 aa)
CUL1Cullin 1; Belongs to the cullin family. (768 aa)
CUL4ACullin 4A; Belongs to the cullin family. (617 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (341 aa)
ENSAPLP00000023897Uncharacterized protein. (208 aa)
CDC27Cell division cycle 27. (834 aa)
RRP8Uncharacterized protein. (716 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1525 aa)
SMURF1E3 ubiquitin-protein ligase. (788 aa)
MID1Midline 1. (667 aa)
XIAPX-linked inhibitor of apoptosis. (493 aa)
FBXW7F-box and WD repeat domain containing 7. (754 aa)
FBXO4F-box protein 4. (318 aa)
PRKNParkin RBR E3 ubiquitin protein ligase. (520 aa)
HERC4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1056 aa)
BRCA1BRCA1 DNA repair associated. (1846 aa)
TRIM37Tripartite motif containing 37. (1025 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (115 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (87 aa)
TRIM32Tripartite motif containing 32. (715 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
UBE4AUbiquitination factor E4A. (1212 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (116 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1331 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
KLHL13Kelch like family member 13. (670 aa)
ENSAPLP00000030796Uncharacterized protein. (1090 aa)
DET1Uncharacterized protein. (572 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
CDC23Cell division cycle 23. (722 aa)
UBE2H-2UBIQUITIN_CONJUGAT_2 domain-containing protein. (151 aa)
TRIP12Thyroid hormone receptor interactor 12. (2035 aa)
CUL3Cullin 3; Belongs to the cullin family. (1175 aa)
UBA7UBA_e1_C domain-containing protein. (562 aa)
UBOX5U-box domain containing 5. (545 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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