95 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U3HZQ3_ANAPP	Uncharacterized protein; Belongs to the peptidase C14A family. (268 aa)
	ATF4	Activating transcription factor 4. (354 aa)
	U3I2P0_ANAPP	Uncharacterized protein. (684 aa)
	U3I3J8_ANAPP	Uncharacterized protein. (207 aa)
	BAK1	BCL2 antagonist/killer 1. (306 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2613 aa)
	DFFB	DNA fragmentation factor subunit beta. (332 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (944 aa)
	CASP2	Caspase 2; Belongs to the peptidase C14A family. (426 aa)
	ENDOG	Endonuclease. (303 aa)
	FADD	Uncharacterized protein. (195 aa)
	BIRC2	Uncharacterized protein. (611 aa)
	MAPK10	Mitogen-activated protein kinase. (384 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
	U3IFF2_ANAPP	Uncharacterized protein; Belongs to the intermediate filament family. (586 aa)
	DIABLO	Uncharacterized protein. (241 aa)
	U3IGX0_ANAPP	Uncharacterized protein. (463 aa)
	U3IH65_ANAPP	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
	U3IJ51_ANAPP	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	ERN1	Endoplasmic reticulum to nucleus signaling 1. (958 aa)
	TUBA8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (446 aa)
	BID	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
	NRAS	Uncharacterized protein. (189 aa)
	CAPN2	Calpain 2; Belongs to the peptidase C2 family. (700 aa)
	TUBA4A	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (430 aa)
	CASP6	Caspase 6; Belongs to the peptidase C14A family. (295 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1247 aa)
	U3ITT3_ANAPP	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	NFKBIA	ANK_REP_REGION domain-containing protein. (318 aa)
	LMNB2	Lamin B2; Belongs to the intermediate filament family. (600 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	PIK3R2	Uncharacterized protein. (731 aa)
	BCL2L11	BCL2 like 11. (159 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	CTSO	Cathepsin O; Belongs to the peptidase C1 family. (354 aa)
	CTSS	Cathepsin S; Belongs to the peptidase C1 family. (330 aa)
	ATM	Non-specific serine/threonine protein kinase. (2967 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	CASP7	Caspase 7; Belongs to the peptidase C14A family. (309 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (992 aa)
	CTSL	Uncharacterized protein; Belongs to the peptidase C1 family. (338 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (676 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (466 aa)
	SPTAN1	Spectrin alpha, non-erythrocytic 1. (2433 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2699 aa)
	U3J6D9_ANAPP	Uncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
	CASP10	Caspase 10; Belongs to the peptidase C14A family. (538 aa)
	CFLAR	CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (489 aa)
	U3J6Z6_ANAPP	Uncharacterized protein. (427 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (690 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (464 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (556 aa)
	CAPN11	Uncharacterized protein; Belongs to the peptidase C2 family. (800 aa)
	MAP3K5	Mitogen-activated protein kinase kinase kinase 5. (1219 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	TNFSF10	TNF superfamily member 10; Belongs to the tumor necrosis factor family. (295 aa)
	BCL2A1	BCL2 related protein A1. (172 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (293 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (998 aa)
	MAPK8	Mitogen-activated protein kinase. (384 aa)
	FAS	Uncharacterized protein. (461 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	AIFM1	Apoptosis inducing factor mitochondria associated 1. (629 aa)
	ENSAPLP00000020346	Fibronectin type-III domain-containing protein. (595 aa)
	ENSAPLP00000021209	Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (579 aa)
	ACTB-2	Uncharacterized protein. (376 aa)
	CTSC	Cathepsin C; Belongs to the peptidase C1 family. (460 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa)
	TRADD	TNFRSF1A associated via death domain. (429 aa)
	XIAP	X-linked inhibitor of apoptosis. (493 aa)
	BCL2L1	BCL2 like 1. (238 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2677 aa)
	LMNB1	Lamin B1; Belongs to the intermediate filament family. (535 aa)
	PTPN13	KIND domain-containing protein. (231 aa)
	DAB2IP	DAB2 interacting protein. (1013 aa)
	ENSAPLP00000027723	calpain_III domain-containing protein. (76 aa)
	TRAF1	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
	EIF2S1	Eukaryotic translation initiation factor 2 subunit alpha. (167 aa)
	CTSD	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (425 aa)
	CTSB	Cathepsin B; Belongs to the peptidase C1 family. (621 aa)
	PARP4	Poly [ADP-ribose] polymerase. (1632 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (778 aa)
	ENSAPLP00000030826	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (121 aa)
	GADD45G	Growth arrest and DNA damage inducible gamma. (238 aa)
	PIDD1	P53-induced death domain protein 1. (892 aa)
	PARP3	Poly [ADP-ribose] polymerase. (729 aa)
	ENSAPLP00000031777	Tubulin domain-containing protein. (142 aa)
	LMNA	Lamin A/C; Belongs to the intermediate filament family. (502 aa)
	GADD45B	Growth arrest and DNA damage inducible beta. (350 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB-2	BCL2	ENSAPLP00000022136	ENSAPLP00000019939	Uncharacterized protein.	BCL2 apoptosis regulator.	0.615
ACTB-2	BCL2L1	ENSAPLP00000022136	ENSAPLP00000025626	Uncharacterized protein.	BCL2 like 1.	0.497
ACTB-2	CASP6	ENSAPLP00000022136	ENSAPLP00000010155	Uncharacterized protein.	Caspase 6; Belongs to the peptidase C14A family.	0.919
ACTB-2	CASP7	ENSAPLP00000022136	ENSAPLP00000013223	Uncharacterized protein.	Caspase 7; Belongs to the peptidase C14A family.	0.927
ACTB-2	CASP8	ENSAPLP00000022136	ENSAPLP00000014720	Uncharacterized protein.	Caspase 8; Belongs to the peptidase C14A family.	0.592
ACTB-2	CASP9	ENSAPLP00000022136	ENSAPLP00000008534	Uncharacterized protein.	Caspase 9; Belongs to the peptidase C14A family.	0.621
ACTB-2	ENSAPLP00000021209	ENSAPLP00000022136	ENSAPLP00000021209	Uncharacterized protein.	Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.476
ACTB-2	ENSAPLP00000030826	ENSAPLP00000022136	ENSAPLP00000030826	Uncharacterized protein.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.480
ACTB-2	ENSAPLP00000031777	ENSAPLP00000022136	ENSAPLP00000031777	Uncharacterized protein.	Tubulin domain-containing protein.	0.491
ACTB-2	KRAS	ENSAPLP00000022136	ENSAPLP00000015839	Uncharacterized protein.	KRAS proto-oncogene, GTPase.	0.414
ACTB-2	LMNB1	ENSAPLP00000022136	ENSAPLP00000027262	Uncharacterized protein.	Lamin B1; Belongs to the intermediate filament family.	0.680
ACTB-2	LMNB2	ENSAPLP00000022136	ENSAPLP00000010840	Uncharacterized protein.	Lamin B2; Belongs to the intermediate filament family.	0.680
ACTB-2	NFKBIA	ENSAPLP00000022136	ENSAPLP00000010772	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.640
ACTB-2	TUBA4A	ENSAPLP00000022136	ENSAPLP00000010045	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.467
ACTB-2	TUBA8	ENSAPLP00000022136	ENSAPLP00000007515	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.477
ACTB-2	U3HZQ3_ANAPP	ENSAPLP00000022136	ENSAPLP00000000473	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.912
ACTB-2	U3IFF2_ANAPP	ENSAPLP00000022136	ENSAPLP00000005974	Uncharacterized protein.	Uncharacterized protein; Belongs to the intermediate filament family.	0.670
ACTB-2	U3IH65_ANAPP	ENSAPLP00000022136	ENSAPLP00000006587	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.464
ACTB-2	U3IJ51_ANAPP	ENSAPLP00000022136	ENSAPLP00000007273	Uncharacterized protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.513
ACTB-2	U3ITT3_ANAPP	ENSAPLP00000022136	ENSAPLP00000010656	Uncharacterized protein.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.480