STRINGSTRING
COL6A2-2 COL6A2-2 U3I0Q1_ANAPP U3I0Q1_ANAPP TNR TNR CAV1 CAV1 LAMC2 LAMC2 ARHGAP35 ARHGAP35 VWF VWF CCND2 CCND2 TNN TNN CAV3 CAV3 EGFR EGFR COL9A3 COL9A3 LAMC1 LAMC1 PARVG PARVG HGF HGF RAC1 RAC1 PDGFRA PDGFRA PIK3CB PIK3CB ZYX ZYX PAK6 PAK6 CHAD CHAD TLN2 TLN2 ITGB3 ITGB3 SHC4 SHC4 PIP5K1C PIP5K1C BIRC2 BIRC2 VEGFC VEGFC KDR KDR MAPK10 MAPK10 FLT4 FLT4 MAPK1 MAPK1 THBS4 THBS4 RASGRF1 RASGRF1 ITGAV ITGAV CRKL CRKL U3IGX0_ANAPP U3IGX0_ANAPP ITGB5 ITGB5 CRK CRK PIK3CD PIK3CD PPP1CB PPP1CB LAMA3 LAMA3 IGF1R IGF1R SHC1 SHC1 ITGA9 ITGA9 ITGB1 ITGB1 MYLK3 MYLK3 ILK ILK THBS2 THBS2 COL4A2 COL4A2 COMP COMP CAPN2 CAPN2 VCL VCL SOS1 SOS1 LAMB1 LAMB1 U3ISQ9_ANAPP U3ISQ9_ANAPP IGF1 IGF1 DOCK1 DOCK1 MET MET LAMB3 LAMB3 RELN RELN AKT3 AKT3 ITGA4 ITGA4 PIK3R2 PIK3R2 ITGB4 ITGB4 EGF EGF HRAS HRAS RAP1B RAP1B PDGFC PDGFC ITGA8 ITGA8 PIK3CA PIK3CA COL4A4 COL4A4 ITGA1 ITGA1 MAPK9 MAPK9 COL4A6 COL4A6 CTNNB1 CTNNB1 RAP1A RAP1A PDGFB PDGFB RAF1 RAF1 PAK5 PAK5 RHOA RHOA COL4A3 COL4A3 PIP5K1A PIP5K1A ARHGAP5 ARHGAP5 PAK2 PAK2 MAP2K1 MAP2K1 RAPGEF1 RAPGEF1 ITGA6 ITGA6 PTEN PTEN PDPK1 PDPK1 RAC3 RAC3 RAC2 RAC2 PIP5K1B PIP5K1B PARVA PARVA AKT1 AKT1 SHC2 SHC2 ITGA3 ITGA3 COL6A3 COL6A3 ITGA11 ITGA11 PAK4 PAK4 PTK2 PTK2 PIK3R1 PIK3R1 MAPK8 MAPK8 ITGB8 ITGB8 CCND1 CCND1 PRKCA PRKCA LAMA4-2 LAMA4-2 PAK1 PAK1 BCL2 BCL2 FLT1 FLT1 ACTN1 ACTN1 PARVB PARVB CDC42 CDC42 ENSAPLP00000021377 ENSAPLP00000021377 COL4A5 COL4A5 FLNB FLNB THBS1 THBS1 ACTB-2 ACTB-2 PDGFRB PDGFRB SOS2 SOS2 PDGFD PDGFD LAMA2 LAMA2 PAK3 PAK3 VAV2 VAV2 LAMA5 LAMA5 XIAP XIAP TNXB TNXB VAV3 VAV3 MYLK4 MYLK4 GSK3B GSK3B VAV1 VAV1 PXN-2 PXN-2 COL9A2 COL9A2 PRKCB PRKCB ENSAPLP00000028084 ENSAPLP00000028084 VEGFD VEGFD ROCK2 ROCK2 MYL9 MYL9 PPP1R12A PPP1R12A CAV2 CAV2 PDGFA PDGFA COL6A1 COL6A1 GRB2 GRB2 LAMB4 LAMB4 ROCK1 ROCK1 CCND3 CCND3 COL1A2 COL1A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL6A2-2VWFA domain-containing protein. (251 aa)
U3I0Q1_ANAPPUncharacterized protein. (165 aa)
TNRTenascin R. (1353 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
LAMC2Laminin subunit gamma 2. (1173 aa)
ARHGAP35Rho GTPase activating protein 35. (1505 aa)
VWFVon Willebrand factor. (2756 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (344 aa)
TNNTenascin N. (1123 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
EGFRReceptor protein-tyrosine kinase. (1219 aa)
COL9A3Uncharacterized protein. (678 aa)
LAMC1Laminin subunit gamma 1. (1574 aa)
PARVGParvin gamma. (309 aa)
HGFUncharacterized protein. (183 aa)
RAC1Rac family small GTPase 1. (192 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1103 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
ZYXZyxin. (555 aa)
PAK6Non-specific serine/threonine protein kinase. (693 aa)
CHADUncharacterized protein. (359 aa)
TLN2Talin 2. (2538 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (1055 aa)
SHC4SHC adaptor protein 4. (631 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (581 aa)
BIRC2Uncharacterized protein. (611 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1373 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
THBS4Uncharacterized protein. (1048 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1176 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1044 aa)
CRKLCRK like proto-oncogene, adaptor protein. (301 aa)
U3IGX0_ANAPPUncharacterized protein. (463 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (894 aa)
CRKCRK proto-oncogene, adaptor protein. (306 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
LAMA3Uncharacterized protein. (1412 aa)
IGF1RTyrosine-protein kinase receptor. (1363 aa)
SHC1SHC adaptor protein 1. (616 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1027 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (1022 aa)
MYLK3Myosin light chain kinase 3. (782 aa)
ILKIntegrin linked kinase. (500 aa)
THBS2Thrombospondin 2. (1182 aa)
COL4A2Collagen IV NC1 domain-containing protein. (524 aa)
COMPUncharacterized protein. (765 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (700 aa)
VCLVinculin. (1135 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1323 aa)
LAMB1Laminin subunit beta 1. (1781 aa)
U3ISQ9_ANAPPUncharacterized protein. (225 aa)
IGF1Insulin like growth factor 1. (153 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1863 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1382 aa)
LAMB3Laminin subunit beta 3. (1255 aa)
RELNReelin. (3456 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (998 aa)
PIK3R2Uncharacterized protein. (731 aa)
ITGB4Integrin beta. (1780 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1182 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
PDGFCPlatelet derived growth factor C. (345 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1050 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
COL4A4Collagen IV NC1 domain-containing protein. (442 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
COL4A6Collagen type IV alpha 6 chain. (1694 aa)
CTNNB1Catenin beta 1. (781 aa)
RAP1AUncharacterized protein. (184 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (251 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (676 aa)
PAK5CRIB domain-containing protein. (344 aa)
RHOARas homolog family member A. (193 aa)
COL4A3Collagen IV NC1 domain-containing protein. (494 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (636 aa)
ARHGAP5Rho GTPase activating protein 5. (1506 aa)
PAK2CRIB domain-containing protein. (161 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (464 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (773 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1082 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (556 aa)
RAC3Rac family small GTPase 3. (189 aa)
RAC2Rac family small GTPase 2. (192 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (556 aa)
PARVAParvin alpha. (372 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
SHC2Uncharacterized protein. (781 aa)
ITGA3Uncharacterized protein. (72 aa)
COL6A3Collagen type VI alpha 3 chain. (3211 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1191 aa)
PAK4P21 (RAC1) activated kinase 4. (639 aa)
PTK2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1119 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (786 aa)
CCND1Cyclin_C domain-containing protein. (153 aa)
PRKCAProtein kinase C. (649 aa)
LAMA4-2Uncharacterized protein. (69 aa)
PAK1CRIB domain-containing protein. (170 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1327 aa)
ACTN1Actinin alpha 1. (914 aa)
PARVBUncharacterized protein. (119 aa)
CDC42Cell division cycle 42. (282 aa)
ENSAPLP00000021377Protein kinase domain-containing protein. (177 aa)
COL4A5Collagen IV NC1 domain-containing protein. (1535 aa)
FLNBFilamin B. (2724 aa)
THBS1Thrombospondin 1. (1178 aa)
ACTB-2Uncharacterized protein. (376 aa)
PDGFRBPlatelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1093 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa)
PDGFDPlatelet derived growth factor D. (577 aa)
LAMA2Uncharacterized protein. (1987 aa)
PAK3Non-specific serine/threonine protein kinase. (562 aa)
VAV2Vav guanine nucleotide exchange factor 2. (854 aa)
LAMA5Laminin subunit alpha 5. (3194 aa)
XIAPX-linked inhibitor of apoptosis. (493 aa)
TNXBUncharacterized protein. (201 aa)
VAV3Vav guanine nucleotide exchange factor 3. (790 aa)
MYLK4Myosin light chain kinase family member 4. (714 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
VAV1Calponin-homology (CH) domain-containing protein. (81 aa)
PXN-2Uncharacterized protein. (636 aa)
COL9A2Collagen type IX alpha 2 chain. (677 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (745 aa)
ENSAPLP00000028084Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1315 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1488 aa)
MYL9Myosin light chain 9. (310 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1090 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (237 aa)
COL6A1VWFA domain-containing protein. (621 aa)
GRB2Growth factor receptor bound protein 2. (203 aa)
LAMB4Laminin N-terminal domain-containing protein. (75 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
CCND3Cyclin_C domain-containing protein; Belongs to the cyclin family. (321 aa)
COL1A2Collagen type I alpha 2 chain. (1363 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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