98 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK13	Mitogen-activated protein kinase 13. (158 aa)
	TNFAIP3	TNF alpha induced protein 3. (870 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (575 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2613 aa)
	MAVS	CARD_2 domain-containing protein. (619 aa)
	U3I6M6_ANAPP	Uncharacterized protein. (184 aa)
	MAPK12	Mitogen-activated protein kinase. (361 aa)
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	FADD	Uncharacterized protein. (195 aa)
	U3IBK2_ANAPP	Uncharacterized protein. (566 aa)
	BIRC2	Uncharacterized protein. (611 aa)
	MAPK10	Mitogen-activated protein kinase. (384 aa)
	IL18	Interleukin-18. (197 aa)
	CASR	Calcium sensing receptor. (1059 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
	VDAC3	Voltage dependent anion channel 3. (296 aa)
	TRAF5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (552 aa)
	YWHAE	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
	SUGT1	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (336 aa)
	TANK	TRAF family member associated NFKB activator. (481 aa)
	TRPM2	Nudix hydrolase domain-containing protein. (1508 aa)
	TBK1	TANK binding kinase 1. (600 aa)
	TXN	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	CYBB	Cytochrome b-245 beta chain. (570 aa)
	MCU	Mitochondrial calcium uniporter. (354 aa)
	U3IRD8_ANAPP	Uncharacterized protein. (934 aa)
	NFKBIA	ANK_REP_REGION domain-containing protein. (318 aa)
	IFNAR1	Interferon alpha and beta receptor subunit 1. (584 aa)
	IFNAR2	Uncharacterized protein. (532 aa)
	JAK1	Tyrosine-protein kinase. (1152 aa)
	BD2	Uncharacterized protein. (64 aa)
	VDAC2	Voltage dependent anion channel 2. (296 aa)
	MFN2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (735 aa)
	MFN1	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (743 aa)
	TLR4	Toll like receptor 4. (843 aa)
	CXCL8-3	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
	STAT1	Signal transducer and activator of transcription. (869 aa)
	ATG16L1	WD_REPEATS_REGION domain-containing protein. (608 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	U3J1K3_ANAPP	Uncharacterized protein; Belongs to the peptidase C14A family. (284 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1175 aa)
	NLRX1	NLR family member X1. (973 aa)
	IKBKE	Inhibitor of nuclear factor kappa B kinase subunit epsilon. (725 aa)
	RHOA	Ras homolog family member A. (193 aa)
	PKN2	Protein kinase N2. (946 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (466 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2699 aa)
	U3J6D9_ANAPP	Uncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
	VDAC1	Voltage dependent anion channel 1. (283 aa)
	TRPM7	Transient receptor potential cation channel subfamily M member 7. (1821 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (690 aa)
	DHX33	Helicase C-terminal domain-containing protein. (405 aa)
	PANX1	Pannexin; Structural component of the gap junctions and the hemichannels. (576 aa)
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (531 aa)
	HSP90AA1	Uncharacterized protein. (362 aa)
	CCL5	C-C motif chemokine. (90 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (315 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (998 aa)
	MAPK8	Mitogen-activated protein kinase. (384 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	IL6	Uncharacterized protein. (350 aa)
	ENSAPLP00000021652	Uncharacterized protein. (243 aa)
	STING1	Transmembrane protein 173. (420 aa)
	IRAK4	Interleukin 1 receptor associated kinase 4. (541 aa)
	GABARAPL2	GABA type A receptor associated protein like 2. (117 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (951 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7. (644 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa)
	DNM1L	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (750 aa)
	XIAP	X-linked inhibitor of apoptosis. (493 aa)
	CXCL8-5	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (277 aa)
	BCL2L1	BCL2 like 1. (238 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2677 aa)
	CXCL8-6	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (155 aa)
	ANTXRL	ANTXR like. (557 aa)
	ERBIN	Erbb2 interacting protein. (1455 aa)
	IRF7	Interferon regulatory factor 7. (523 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (311 aa)
	ENSAPLP00000028410	Uncharacterized protein. (157 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (706 aa)
	NEK7	NIMA related kinase 7; Belongs to the protein kinase superfamily. (352 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	GPRC6A	ANF_receptor domain-containing protein. (453 aa)
	CTSB	Cathepsin B; Belongs to the peptidase C1 family. (621 aa)
	TP53BP1	Tumor protein p53 binding protein 1. (1970 aa)
	BRCC3	BRCA1/BRCA2-containing complex subunit 3. (306 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (778 aa)
	RNASEL	Uncharacterized protein. (772 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (217 aa)
	TICAM1	TRIF-NTD domain-containing protein. (507 aa)
	PSTPIP1	Proline-serine-threonine phosphatase interacting protein 1. (406 aa)
	NAMPT	Nicotinamide phosphoribosyltransferase. (541 aa)
	ENSAPLP00000031805	Uncharacterized protein. (192 aa)
	TXN2	Thioredoxin 2. (65 aa)
	ENSAPLP00000032274	Protein kinase domain-containing protein. (192 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG16L1	ENSAPLP00000030549	ENSAPLP00000013185	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	WD_REPEATS_REGION domain-containing protein.	0.999
ATG12	ATG5	ENSAPLP00000030549	ENSAPLP00000018253	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	BCL2	ENSAPLP00000030549	ENSAPLP00000019939	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	BCL2 apoptosis regulator.	0.613
ATG12	CASP8	ENSAPLP00000030549	ENSAPLP00000014720	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Caspase 8; Belongs to the peptidase C14A family.	0.574
ATG12	DNM1L	ENSAPLP00000030549	ENSAPLP00000024626	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.482
ATG12	FADD	ENSAPLP00000030549	ENSAPLP00000004592	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.611
ATG12	GABARAPL2	ENSAPLP00000030549	ENSAPLP00000023898	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	GABA type A receptor associated protein like 2.	0.990
ATG12	MAVS	ENSAPLP00000030549	ENSAPLP00000002790	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	CARD_2 domain-containing protein.	0.975
ATG12	MFN1	ENSAPLP00000030549	ENSAPLP00000012358	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.677
ATG12	MFN2	ENSAPLP00000030549	ENSAPLP00000012292	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.677
ATG12	NLRX1	ENSAPLP00000030549	ENSAPLP00000013893	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	NLR family member X1.	0.555
ATG12	U3J6D9_ANAPP	ENSAPLP00000030549	ENSAPLP00000015066	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.594
ATG12	VDAC1	ENSAPLP00000030549	ENSAPLP00000015140	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Voltage dependent anion channel 1.	0.643
ATG12	VDAC2	ENSAPLP00000030549	ENSAPLP00000012279	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Voltage dependent anion channel 2.	0.597
ATG12	VDAC3	ENSAPLP00000030549	ENSAPLP00000006137	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Voltage dependent anion channel 3.	0.597
ATG16L1	ATG12	ENSAPLP00000013185	ENSAPLP00000030549	WD_REPEATS_REGION domain-containing protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG16L1	ATG5	ENSAPLP00000013185	ENSAPLP00000018253	WD_REPEATS_REGION domain-containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG16L1	GABARAPL2	ENSAPLP00000013185	ENSAPLP00000023898	WD_REPEATS_REGION domain-containing protein.	GABA type A receptor associated protein like 2.	0.984
ATG16L1	NLRX1	ENSAPLP00000013185	ENSAPLP00000013893	WD_REPEATS_REGION domain-containing protein.	NLR family member X1.	0.551
ATG16L1	NOD1	ENSAPLP00000013185	ENSAPLP00000023952	WD_REPEATS_REGION domain-containing protein.	Nucleotide binding oligomerization domain containing 1.	0.966