STRINGSTRING
IFNGR1 IFNGR1 U3I3U3_ANAPP U3I3U3_ANAPP TSC1 TSC1 BAK1 BAK1 MAVS MAVS SRPK1 SRPK1 U3I6M6_ANAPP U3I6M6_ANAPP PIK3CB PIK3CB SYK SYK SRSF2 SRSF2 EIF2AK1 EIF2AK1 ITGB3 ITGB3 U3IA71_ANAPP U3IA71_ANAPP FADD FADD BIRC2 BIRC2 EIF2B5 EIF2B5 IL12A IL12A TRAF5 TRAF5 SRSF4 SRSF4 U3IGX0_ANAPP U3IGX0_ANAPP HCFC2 HCFC2 MTOR MTOR C5 C5 PIK3CD PIK3CD PPP1CB PPP1CB TBK1 TBK1 CASP9 CASP9 BID BID IL12B IL12B EIF2B2 EIF2B2 APAF1 APAF1 CALR3 CALR3 U3ITT3_ANAPP U3ITT3_ANAPP IFIH1 IFIH1 NFKBIA NFKBIA IFNGR2 IFNGR2 IFNAR1 IFNAR1 EIF2B3 EIF2B3 IFNAR2 IFNAR2 TLR2 TLR2 AKT3 AKT3 PIK3R2 PIK3R2 SOCS3 SOCS3 JAK1 JAK1 U3IXJ5_ANAPP U3IXJ5_ANAPP SRSF7 SRSF7 IFNG IFNG PIK3CA PIK3CA STAT1 STAT1 IKBKE IKBKE SRSF6 SRSF6 SRSF5 SRSF5 EIF2B1 EIF2B1 CASP8 CASP8 U3J6D9_ANAPP U3J6D9_ANAPP TAP2 TAP2 U3J6Z6_ANAPP U3J6Z6_ANAPP EIF4EBP1 EIF4EBP1 U3J954_ANAPP U3J954_ANAPP AKT1 AKT1 TAB1 TAB1 CCL5 CCL5 ENSAPLP00000017757 ENSAPLP00000017757 PIK3R1 PIK3R1 ENSAPLP00000017990 ENSAPLP00000017990 NFKB1 NFKB1 FAS FAS BCL2 BCL2 IL6 IL6 POU2F3 POU2F3 ENSAPLP00000021652 ENSAPLP00000021652 STING1 STING1 POU2F1 POU2F1 IRAK4 IRAK4 SRSF1 SRSF1 MAP3K7 MAP3K7 TRAF2 TRAF2 TRADD TRADD BCL2L1 BCL2L1 ENSAPLP00000026075 ENSAPLP00000026075 IRF7 IRF7 JAK2 JAK2 EIF2S1 EIF2S1 ENSAPLP00000027886 ENSAPLP00000027886 TRAF6 TRAF6 ENSAPLP00000028074 ENSAPLP00000028074 MYD88 MYD88 ENSAPLP00000028410 ENSAPLP00000028410 TAB2 TAB2 TRAF3 TRAF3 IKBKB IKBKB RNASEL RNASEL ENSAPLP00000030796 ENSAPLP00000030796 ENSAPLP00000030826 ENSAPLP00000030826 TICAM1 TICAM1 ENSAPLP00000032274 ENSAPLP00000032274 RHEB RHEB CD74 CD74
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFNGR1Interferon gamma receptor 1. (438 aa)
U3I3U3_ANAPPUncharacterized protein. (279 aa)
TSC1TSC complex subunit 1. (1158 aa)
BAK1BCL2 antagonist/killer 1. (306 aa)
MAVSCARD_2 domain-containing protein. (619 aa)
SRPK1SRSF protein kinase 1. (664 aa)
U3I6M6_ANAPPUncharacterized protein. (184 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
SRSF2RRM domain-containing protein. (221 aa)
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (645 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (1055 aa)
U3IA71_ANAPPMHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (189 aa)
FADDUncharacterized protein. (195 aa)
BIRC2Uncharacterized protein. (611 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (708 aa)
IL12AInterleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (214 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
SRSF4Serine and arginine rich splicing factor 4. (499 aa)
U3IGX0_ANAPPUncharacterized protein. (463 aa)
HCFC2Host cell factor C2. (807 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
C5Complement C5. (880 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
TBK1TANK binding kinase 1. (600 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (446 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (348 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1247 aa)
CALR3Calreticulin. (389 aa)
U3ITT3_ANAPPCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
IFIH1Interferon induced with helicase C domain 1. (1003 aa)
NFKBIAANK_REP_REGION domain-containing protein. (318 aa)
IFNGR2Interferon gamma receptor 2. (338 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (584 aa)
EIF2B3Uncharacterized protein. (373 aa)
IFNAR2Uncharacterized protein. (532 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3R2Uncharacterized protein. (731 aa)
SOCS3Suppressor of cytokine signaling 3. (209 aa)
JAK1Tyrosine-protein kinase. (1152 aa)
U3IXJ5_ANAPPUncharacterized protein. (218 aa)
SRSF7Uncharacterized protein. (250 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
STAT1Signal transducer and activator of transcription. (869 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (725 aa)
SRSF6Serine and arginine rich splicing factor 6. (348 aa)
SRSF5Serine and arginine rich splicing factor 5. (267 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (330 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (466 aa)
U3J6D9_ANAPPUncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
TAP2Uncharacterized protein. (606 aa)
U3J6Z6_ANAPPUncharacterized protein. (427 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (100 aa)
U3J954_ANAPPTyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (660 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (531 aa)
CCL5C-C motif chemokine. (90 aa)
ENSAPLP00000017757Uncharacterized protein. (545 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSAPLP00000017990KRAB domain-containing protein. (82 aa)
NFKB1Nuclear factor kappa B subunit 1. (998 aa)
FASUncharacterized protein. (461 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
IL6Uncharacterized protein. (350 aa)
POU2F3POU domain protein. (477 aa)
ENSAPLP00000021652Uncharacterized protein. (243 aa)
STING1Transmembrane protein 173. (420 aa)
POU2F1POU domain protein. (775 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (541 aa)
SRSF1Uncharacterized protein. (247 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (644 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa)
TRADDTNFRSF1A associated via death domain. (429 aa)
BCL2L1BCL2 like 1. (238 aa)
ENSAPLP00000026075Uncharacterized protein. (1206 aa)
IRF7Interferon regulatory factor 7. (523 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (167 aa)
ENSAPLP00000027886Uncharacterized protein. (670 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
ENSAPLP00000028074KRAB domain-containing protein. (520 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (311 aa)
ENSAPLP00000028410Uncharacterized protein. (157 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (706 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (778 aa)
RNASELUncharacterized protein. (772 aa)
ENSAPLP00000030796Uncharacterized protein. (1090 aa)
ENSAPLP00000030826Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (121 aa)
TICAM1TRIF-NTD domain-containing protein. (507 aa)
ENSAPLP00000032274Protein kinase domain-containing protein. (192 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
CD74CD74 molecule. (300 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.