STRINGSTRING
malP_1 malP_1 mbtB_1 mbtB_1 alr alr CUO02114.1 CUO02114.1 iscS iscS nifS nifS cobD_2 cobD_2 kbl kbl glyA glyA porA porA dxs_1 dxs_1 dxs_2 dxs_2 CUO09800.1 CUO09800.1 metH metH argD_2 argD_2 thiN thiN patB_2 patB_2 malP_2 malP_2 dapL dapL csd_2 csd_2 patB_3 patB_3 CUO37428.1 CUO37428.1 mccB mccB mdeA_1 mdeA_1 CUN54001.1 CUN54001.1 tdcB tdcB lysA lysA serC serC ilvB_2 ilvB_2 cobD_1 cobD_1 mog_1 mog_1 mdeA_2 mdeA_2 ilvB_1 ilvB_1 patA patA hemN_2 hemN_2 argD_1 argD_1 aspC aspC hisC hisC iorA iorA gabR gabR CUN46641.1 CUN46641.1 patB_1 patB_1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
malP_1Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (825 aa)
mbtB_1Phenyloxazoline synthase MbtB. (1513 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (387 aa)
CUO02114.1Predicted enzyme with a TIM-barrel fold; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (232 aa)
iscSCysteine desulfurase. (386 aa)
nifSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (398 aa)
cobD_2Threonine-phosphate decarboxylase. (348 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (400 aa)
glyAPyridoxal-phosphate-dependent serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
porAPyruvate synthase subunit porA. (1180 aa)
dxs_11-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (584 aa)
dxs_21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (620 aa)
CUO09800.1Vitamin B12 dependent methionine synthase%2C activation domain. (214 aa)
metHMethionine synthase. (796 aa)
argD_2Acetylornithine aminotransferase. (409 aa)
thiNThiamine pyrophosphokinase. (219 aa)
patB_2Cystathionine beta-lyase PatB. (403 aa)
malP_2Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (752 aa)
dapLLL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (404 aa)
csd_2Probable cysteine desulfurase. (384 aa)
patB_3Cystathionine beta-lyase PatB. (388 aa)
CUO37428.1Putative aminotransferase MSMEG_6286. (435 aa)
mccBCystathionine gamma-lyase. (381 aa)
mdeA_1Methionine gamma-lyase. (436 aa)
CUN54001.1Indolepyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (607 aa)
tdcBL-threonine dehydratase catabolic TdcB. (404 aa)
lysADiaminopimelate decarboxylase. (424 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa)
ilvB_2Acetolactate synthase large subunit. (561 aa)
cobD_1Threonine-phosphate decarboxylase. (362 aa)
mog_1Molybdopterin adenylyltransferase. (322 aa)
mdeA_2Methionine gamma-lyase. (427 aa)
ilvB_1Acetolactate synthase large subunit. (573 aa)
patAPutative aminotransferase A. (390 aa)
hemN_2Oxygen-independent coproporphyrinogen-III oxidase. (595 aa)
argD_1Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (395 aa)
aspCAspartate aminotransferase. (395 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (351 aa)
iorAIndolepyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (582 aa)
gabRHTH-type transcriptional regulatory protein gabR. (465 aa)
CUN46641.1Aspartate aminotransferase. (405 aa)
patB_1Cystathionine beta-lyase PatB. (391 aa)
Your Current Organism:
Dorea longicatena
NCBI taxonomy Id: 88431
Other names: CCUG 45247, D. longicatena, DSM 13814, Dorea longicatena Taras et al. 2002, Eubacterium sp. III-35, JCM 11232, strain 111-35
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