(20 nodes) T cell selection network (Anser cygnoides)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSACDP00005003603	annotation not available (192 aa)
	PTPRC	Receptor-type tyrosine-protein phosphatase C isoform X1. (1260 aa)
	BATF	Basic leucine zipper ATF-like transcription factor. (124 aa)
	IL6R	Interleukin 6 receptor. (396 aa)
	BCL11B	B-cell lymphoma/leukemia 11B isoform X1. (883 aa)
	CCR7	C-C chemokine receptor type 7. (374 aa)
	CD4	T-cell surface glycoprotein CD4 isoform X1. (523 aa)
	MTOR	Serine/threonine-protein kinase mTOR isoform X1. (2535 aa)
	CARD11	Caspase recruitment domain-containing protein 11 isoform X1. (1169 aa)
	BCL2	BCL2 apoptosis regulator. (359 aa)
	IL6	Interleukin 6. (234 aa)
	THEMIS	LOW QUALITY PROTEIN: protein THEMIS. (691 aa)
	CD3D	T-cell surface glycoprotein CD3 delta chain isoform X1. (326 aa)
	CD3E	T-cell surface glycoprotein CD3 epsilon chain. (190 aa)
	TOX	Thymocyte selection-associated high mobility group box protein TOX isoform X1. (507 aa)
	SRF	Serum response factor. (506 aa)
	ZAP70	Tyrosine-protein kinase ZAP-70 isoform X1. (607 aa)
	JAG2	Protein jagged-2. (1290 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
	IL15	Interleukin 15. (183 aa)

Your Current Organism:

Anser cygnoides

NCBI taxonomy Id: 8845
Other names: A. cygnoides, Chinese goose, Swan goose, white Chinese goose

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BATF	BCL11B	ENSACDP00005006422	ENSACDP00005011738	Basic leucine zipper ATF-like transcription factor.	B-cell lymphoma/leukemia 11B isoform X1.	0.497
BATF	CD4	ENSACDP00005006422	ENSACDP00005012510	Basic leucine zipper ATF-like transcription factor.	T-cell surface glycoprotein CD4 isoform X1.	0.412
BCL11B	BATF	ENSACDP00005011738	ENSACDP00005006422	B-cell lymphoma/leukemia 11B isoform X1.	Basic leucine zipper ATF-like transcription factor.	0.497
BCL11B	GATA3	ENSACDP00005011738	ENSACDP00005026722	B-cell lymphoma/leukemia 11B isoform X1.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.448
BCL2	CD4	ENSACDP00005015579	ENSACDP00005012510	BCL2 apoptosis regulator.	T-cell surface glycoprotein CD4 isoform X1.	0.738
BCL2	ENSACDP00005003603	ENSACDP00005015579	ENSACDP00005003603	BCL2 apoptosis regulator.	annotation not available	0.761
BCL2	IL6	ENSACDP00005015579	ENSACDP00005018189	BCL2 apoptosis regulator.	Interleukin 6.	0.801
CARD11	ZAP70	ENSACDP00005014216	ENSACDP00005024758	Caspase recruitment domain-containing protein 11 isoform X1.	Tyrosine-protein kinase ZAP-70 isoform X1.	0.536
CCR7	CD3D	ENSACDP00005011919	ENSACDP00005018601	C-C chemokine receptor type 7.	T-cell surface glycoprotein CD3 delta chain isoform X1.	0.496
CCR7	CD3E	ENSACDP00005011919	ENSACDP00005018608	C-C chemokine receptor type 7.	T-cell surface glycoprotein CD3 epsilon chain.	0.501
CCR7	CD4	ENSACDP00005011919	ENSACDP00005012510	C-C chemokine receptor type 7.	T-cell surface glycoprotein CD4 isoform X1.	0.836
CCR7	IL15	ENSACDP00005011919	ENSACDP00005002918	C-C chemokine receptor type 7.	Interleukin 15.	0.545
CCR7	IL6	ENSACDP00005011919	ENSACDP00005018189	C-C chemokine receptor type 7.	Interleukin 6.	0.663
CCR7	PTPRC	ENSACDP00005011919	ENSACDP00005005185	C-C chemokine receptor type 7.	Receptor-type tyrosine-protein phosphatase C isoform X1.	0.463
CD3D	CCR7	ENSACDP00005018601	ENSACDP00005011919	T-cell surface glycoprotein CD3 delta chain isoform X1.	C-C chemokine receptor type 7.	0.496
CD3D	CD3E	ENSACDP00005018601	ENSACDP00005018608	T-cell surface glycoprotein CD3 delta chain isoform X1.	T-cell surface glycoprotein CD3 epsilon chain.	0.998
CD3D	CD4	ENSACDP00005018601	ENSACDP00005012510	T-cell surface glycoprotein CD3 delta chain isoform X1.	T-cell surface glycoprotein CD4 isoform X1.	0.714
CD3D	PTPRC	ENSACDP00005018601	ENSACDP00005005185	T-cell surface glycoprotein CD3 delta chain isoform X1.	Receptor-type tyrosine-protein phosphatase C isoform X1.	0.653
CD3D	ZAP70	ENSACDP00005018601	ENSACDP00005024758	T-cell surface glycoprotein CD3 delta chain isoform X1.	Tyrosine-protein kinase ZAP-70 isoform X1.	0.929
CD3E	CCR7	ENSACDP00005018608	ENSACDP00005011919	T-cell surface glycoprotein CD3 epsilon chain.	C-C chemokine receptor type 7.	0.501