STRINGSTRING
UBE4B UBE4B H920_05086 H920_05086 SENP1 SENP1 UBL7 UBL7 HLTF HLTF PIAS4 PIAS4 UBR2 UBR2 ZMIZ1 ZMIZ1 ENSFDAP00000001970 ENSFDAP00000001970 UBE2R2 UBE2R2 ENSFDAP00000002920 ENSFDAP00000002920 KCTD2 KCTD2 UBA2 UBA2 ABRAXAS1 ABRAXAS1 SHPRH SHPRH ENSFDAP00000003729 ENSFDAP00000003729 PIAS3 PIAS3 Babam1 Babam1 Brcc3 Brcc3 Ube2d3 Ube2d3 CDC34 CDC34 STUB1 STUB1 UBE2Z UBE2Z UBE2A UBE2A ENSFDAP00000006015 ENSFDAP00000006015 RNF40 RNF40 ENSFDAP00000006648 ENSFDAP00000006648 UBE2J1 UBE2J1 Sumo2 Sumo2 ENSFDAP00000007168 ENSFDAP00000007168 TDG TDG ENSFDAP00000007247 ENSFDAP00000007247 UBE2I UBE2I UBE2QL1 UBE2QL1 SAE1 SAE1 OTUB2 OTUB2 TRIP12 TRIP12 RNF165 RNF165 Ube2b Ube2b Lonrf3 Lonrf3 RNF20 RNF20 RNF4 RNF4 LOC104856727 LOC104856727 RLIM RLIM H920_07462 H920_07462 ENSFDAP00000010206 ENSFDAP00000010206 RNF169 RNF169 UBE2G1 UBE2G1 H920_01844 H920_01844 RNF8 RNF8 UBE4A UBE4A Wac Wac UBA7 UBA7 Stat5b Stat5b BABAM2 BABAM2 UBE2V1 UBE2V1 ENSFDAP00000013479 ENSFDAP00000013479 ABRAXAS2 ABRAXAS2 SUMO4 SUMO4 ENSFDAP00000015759 ENSFDAP00000015759 UBE2O UBE2O Sumo3 Sumo3 UBE2K UBE2K UBE2E2 UBE2E2 Lonrf1 Lonrf1 SENP7 SENP7 OTUB1 OTUB1 UBE2E1 UBE2E1 UBE2E3 UBE2E3 ENSFDAP00000017753 ENSFDAP00000017753 ENSFDAP00000017776 ENSFDAP00000017776 PIAS1 PIAS1 RAD18 RAD18 SATB1 SATB1 UBE2H UBE2H H920_04415 H920_04415 ZMIZ2 ZMIZ2 UBR1 UBR1 RNF168 RNF168 UBE2Q1 UBE2Q1 UBE2D2 UBE2D2 UBE2Q2 UBE2Q2 PIAS2 PIAS2 SENP2 SENP2 UBE2V2 UBE2V2 RANGAP1 RANGAP1 UBA1 UBA1 UBE2D4 UBE2D4 SUMO1 SUMO1 LOC104849997 LOC104849997 UBE2D1 UBE2D1 UBA6 UBA6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBE4BUbiquitination factor E4B. (1176 aa)
H920_05086B-lymphocyte antigen CD19. (140 aa)
SENP1Sentrin-specific protease 1. (636 aa)
UBL7Ubiquitin-like protein 7. (380 aa)
HLTFHelicase-like transcription factor. (1006 aa)
PIAS4Protein inhibitor of activated STAT 4. (386 aa)
UBR2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1735 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1. (1076 aa)
ENSFDAP00000001970annotation not available (234 aa)
UBE2R2Ubiquitin-conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
ENSFDAP00000002920annotation not available (87 aa)
KCTD2BTB/POZ domain-containing protein KCTD2. (222 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (624 aa)
ABRAXAS1BRCA1-A complex subunit Abraxas. (359 aa)
SHPRHE3 ubiquitin-protein ligase SHPRH. (1685 aa)
ENSFDAP00000003729annotation not available (135 aa)
PIAS3E3 SUMO-protein ligase PIAS3. (637 aa)
Babam1BRISC and BRCA1 A complex member 1. (293 aa)
Brcc3Lys-63-specific deubiquitinase BRCC36. (288 aa)
Ube2d3Ubiquitin-conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
CDC34Ubiquitin-conjugating enzyme E2 R1; Belongs to the ubiquitin-conjugating enzyme family. (237 aa)
STUB1STIP1 homology and U box-containing protein 1. (250 aa)
UBE2ZCalcium-binding and coiled-coil domain-containing protein 2. (210 aa)
UBE2AUbiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (224 aa)
ENSFDAP00000006015annotation not available (149 aa)
RNF40E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1001 aa)
ENSFDAP00000006648annotation not available (129 aa)
UBE2J1Ubiquitin-conjugating enzyme E2 J1. (307 aa)
Sumo2Small ubiquitin-related modifier 3. (88 aa)
ENSFDAP00000007168annotation not available (110 aa)
TDGG/T mismatch-specific thymine DNA glycosylase. (404 aa)
ENSFDAP00000007247annotation not available (119 aa)
UBE2ISUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
UBE2QL1Ubiquitin conjugating enzyme E2 Q family like 1. (161 aa)
SAE1SUMO-activating enzyme subunit 1. (346 aa)
OTUB2Ubiquitin thioesterase OTUB2. (234 aa)
TRIP12Putative E3 ubiquitin-protein ligase TRIP12. (2026 aa)
RNF165RING finger protein 165. (333 aa)
Ube2bUbiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (137 aa)
Lonrf3LON peptidase N-terminal domain and RING finger protein 3. (217 aa)
RNF20E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa)
RNF4E3 ubiquitin ligase RNF4. (193 aa)
LOC104856727Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
RLIME3 ubiquitin-protein ligase RLIM. (591 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
ENSFDAP00000010206annotation not available (133 aa)
RNF169RING finger protein 169. (609 aa)
UBE2G1Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
H920_01844Polyubiquitin-B. (77 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (449 aa)
UBE4AUbiquitin conjugation factor E4 A. (1065 aa)
WacWW domain-containing adapter protein with coiled-coil. (620 aa)
UBA7Ubiquitin-like modifier-activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1001 aa)
Stat5bSignal transducer and activator of transcription 5B. (736 aa)
BABAM2BRISC and BRCA1 A complex member 2. (409 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (175 aa)
ENSFDAP00000013479annotation not available (466 aa)
ABRAXAS2BRISC complex subunit Abro1. (414 aa)
SUMO4Small ubiquitin-related modifier. (95 aa)
ENSFDAP00000015759annotation not available (147 aa)
UBE2OUbiquitin-conjugating enzyme E2 O. (1139 aa)
Sumo3Small ubiquitin like modifier 3. (115 aa)
UBE2KUbiquitin conjugating enzyme E2 K. (179 aa)
UBE2E2Ubiquitin-conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
Lonrf1LON peptidase N-terminal domain and RING finger protein 1. (389 aa)
SENP7Sentrin-specific protease 7. (1038 aa)
OTUB1Ubiquitin thioesterase. (271 aa)
UBE2E1Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
UBE2E3Ubiquitin-conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
ENSFDAP00000017753annotation not available (63 aa)
ENSFDAP00000017776annotation not available (72 aa)
PIAS1E3 SUMO-protein ligase PIAS1. (647 aa)
RAD18E3 ubiquitin-protein ligase RAD18. (501 aa)
SATB1DNA-binding protein SATB. (793 aa)
UBE2HUbiquitin-conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
H920_04415BRCA1-A complex subunit RAP80. (415 aa)
ZMIZ2Zinc finger MIZ domain-containing protein 2. (920 aa)
UBR1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1753 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (559 aa)
UBE2Q1Ubiquitin conjugating enzyme E2 Q1. (253 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D4; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
UBE2Q2Ubiquitin-conjugating enzyme E2 Q2. (373 aa)
PIAS2E3 SUMO-protein ligase PIAS2. (614 aa)
SENP2SUMO specific peptidase 2. (555 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
RANGAP1Ran GTPase activating protein 1. (585 aa)
UBA1Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1058 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative). (107 aa)
SUMO1Small ubiquitin-related modifier. (110 aa)
LOC104849997Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (290 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
UBA6Ubiquitin-like modifier-activating enzyme 6. (1028 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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