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CUL3 | Cullin-3; Belongs to the cullin family. (770 aa) | ||||
UBOX5 | RING finger protein 37. (541 aa) | ||||
TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) | ||||
UBE4B | Ubiquitination factor E4B. (1176 aa) | ||||
RNF180 | E3 ubiquitin-protein ligase RNF180. (580 aa) | ||||
TRIM62 | Tripartite motif containing 62. (352 aa) | ||||
UBE3D | Ubiquitin-conjugating enzyme E2C-binding protein. (336 aa) | ||||
BTRC | F-box/WD repeat-containing protein 1A. (589 aa) | ||||
G2E3 | G2/M phase-specific E3 ubiquitin-protein ligase. (708 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) | ||||
NHLRC4 | NHL-repeat-containing protein 4. (136 aa) | ||||
CDC23 | Cell division cycle protein 23 like protein. (597 aa) | ||||
KLHL42 | Kelch domain-containing protein 5. (414 aa) | ||||
ANKIB1 | RBR-type E3 ubiquitin transferase. (1081 aa) | ||||
MKRN2 | Putative E3 ubiquitin-protein ligase makorin-2. (417 aa) | ||||
PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) | ||||
FBXW11 | F-box/WD repeat-containing protein 11. (539 aa) | ||||
TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa) | ||||
AMBRA1 | Autophagy and beclin 1 regulator 1. (1235 aa) | ||||
TRIM27 | Tripartite motif containing 27. (461 aa) | ||||
H920_10530 | E3 ubiquitin-protein ligase TTC3. (299 aa) | ||||
RNF6 | E3 ubiquitin-protein ligase RNF6. (672 aa) | ||||
UBE2L6 | Ubiquitin/ISG15-conjugating enzyme E2 L6. (153 aa) | ||||
RNF26 | Ring finger protein 26. (427 aa) | ||||
UBE2R2 | Ubiquitin-conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa) | ||||
RFFL | E3 ubiquitin-protein ligase rififylin. (366 aa) | ||||
RNF115 | E3 ubiquitin-protein ligase RNF115. (306 aa) | ||||
RC3H2 | RING finger and CCCH-type zinc finger domain-containing protein 2. (1188 aa) | ||||
H920_08593 | E3 ubiquitin-protein ligase HECW2. (295 aa) | ||||
TMEM129 | Transmembrane protein 129. (362 aa) | ||||
CBL | E3 ubiquitin-protein ligase CBL. (851 aa) | ||||
SHPRH | E3 ubiquitin-protein ligase SHPRH. (1685 aa) | ||||
H920_17698 | F-box only protein 28. (320 aa) | ||||
ANAPC2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (827 aa) | ||||
Marchf8 | E3 ubiquitin-protein ligase MARCH8. (289 aa) | ||||
ENSFDAP00000003729 | annotation not available (135 aa) | ||||
RNF41 | E3 ubiquitin-protein ligase NRDP1. (317 aa) | ||||
RC3H1 | Roquin. (1133 aa) | ||||
RNF135 | Ring finger protein 135. (389 aa) | ||||
HECW1 | E3 ubiquitin-protein ligase HECW1. (1511 aa) | ||||
Ube2d3 | Ubiquitin-conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) | ||||
CDC16 | Cell division cycle protein 16 like protein. (626 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1737 aa) | ||||
Anapc13 | Anaphase-promoting complex subunit 13. (74 aa) | ||||
FBXO38 | F-box only protein 38. (1189 aa) | ||||
DDA1 | DET1-and DDB1-associated protein 1. (102 aa) | ||||
ZNRF1 | Zinc and ring finger 1. (185 aa) | ||||
TRIM56 | E3 ubiquitin-protein ligase TRIM56. (733 aa) | ||||
NHLRC3 | NHL repeat-containing protein 3. (347 aa) | ||||
ENSFDAP00000004977 | annotation not available (335 aa) | ||||
CDC34 | Ubiquitin-conjugating enzyme E2 R1; Belongs to the ubiquitin-conjugating enzyme family. (237 aa) | ||||
STUB1 | STIP1 homology and U box-containing protein 1. (250 aa) | ||||
CHFR | E3 ubiquitin-protein ligase CHFR. (663 aa) | ||||
ENSFDAP00000005475 | annotation not available (139 aa) | ||||
DTX3L | E3 ubiquitin-protein ligase DTX3L. (738 aa) | ||||
ANAPC5 | Anaphase-promoting complex subunit 5. (755 aa) | ||||
UBE2J2 | Ubiquitin-conjugating enzyme E2 J2. (259 aa) | ||||
UBR5 | E3 ubiquitin-protein ligase UBR5. (2791 aa) | ||||
MARCHF1 | E3 ubiquitin-protein ligase MARCH1. (289 aa) | ||||
UBE3A | Ubiquitin-protein ligase E3A. (874 aa) | ||||
UBE2A | Ubiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (224 aa) | ||||
ENSFDAP00000006015 | annotation not available (149 aa) | ||||
RNF125 | E3 ubiquitin-protein ligase RNF125. (138 aa) | ||||
ENSFDAP00000006648 | annotation not available (129 aa) | ||||
UBE2J1 | Ubiquitin-conjugating enzyme E2 J1. (307 aa) | ||||
RNF185 | RING finger protein 185. (192 aa) | ||||
CDC26 | Transmembrane protein 71. (84 aa) | ||||
DAW1 | WD repeat-containing protein 69. (415 aa) | ||||
SMURF2 | E3 ubiquitin-protein ligase. (742 aa) | ||||
UBE2T | Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (205 aa) | ||||
ENSFDAP00000007247 | annotation not available (119 aa) | ||||
UBE2QL1 | Ubiquitin conjugating enzyme E2 Q family like 1. (161 aa) | ||||
TNKS2 | Tankyrase 2. (1161 aa) | ||||
TRIM14 | Tripartite motif containing 14. (325 aa) | ||||
LRSAM1 | E3 ubiquitin-protein ligase LRSAM1. (718 aa) | ||||
ANAPC1 | Anaphase-promoting complex subunit 1. (1944 aa) | ||||
SKP2 | S-phase kinase-associated protein 2. (424 aa) | ||||
AREL1 | Protein KIAA0317. (823 aa) | ||||
RNF152 | E3 ubiquitin-protein ligase RNF152. (203 aa) | ||||
TRIP12 | Putative E3 ubiquitin-protein ligase TRIP12. (2026 aa) | ||||
TRIM3 | Tripartite motif-containing protein 3. (744 aa) | ||||
RNF165 | RING finger protein 165. (333 aa) | ||||
Ube2b | Ubiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (137 aa) | ||||
RNF20 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa) | ||||
RNF4 | E3 ubiquitin ligase RNF4. (193 aa) | ||||
ANAPC7 | Anaphase-promoting complex subunit 7. (592 aa) | ||||
LOC104856727 | Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) | ||||
Anapc11 | Anaphase-promoting complex subunit 11. (84 aa) | ||||
PELI2 | Protein pellino like protein 2. (351 aa) | ||||
ENSFDAP00000009939 | annotation not available (128 aa) | ||||
H920_00961 | Tripartite motif-containing protein 6. (147 aa) | ||||
UBE3B | Ubiquitin-protein ligase E3B. (1068 aa) | ||||
H920_07462 | Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa) | ||||
RNF167 | E3 ubiquitin-protein ligase RNF167. (347 aa) | ||||
ENSFDAP00000010206 | annotation not available (133 aa) | ||||
MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1347 aa) | ||||
UBE2G1 | Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) | ||||
H920_12355 | Bifunctional polynucleotide phosphatase/kinase. (173 aa) | ||||
TRIML2 | Putative E3 ubiquitin-protein ligase TRIML2. (429 aa) | ||||
TRIM38 | Tripartite motif-containing protein 38. (467 aa) | ||||
HDAC6 | Histone deacetylase 6. (1108 aa) | ||||
ENSFDAP00000011068 | annotation not available (313 aa) | ||||
RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (449 aa) | ||||
RNF144A | RBR-type E3 ubiquitin transferase. (403 aa) | ||||
RBCK1 | RanBP-type and C3HC4-type zinc finger-containing protein 1. (510 aa) | ||||
RNF19A | RBR-type E3 ubiquitin transferase. (837 aa) | ||||
UBE2G2 | Ubiquitin-conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (148 aa) | ||||
UBE4A | Ubiquitin conjugation factor E4 A. (1065 aa) | ||||
Rnf31 | RING finger protein 31. (1069 aa) | ||||
TOPORS | E3 ubiquitin-protein ligase Topors. (969 aa) | ||||
RNF166 | RING finger protein 166. (185 aa) | ||||
RNF216 | E3 ubiquitin-protein ligase RNF216. (917 aa) | ||||
MAGEL2 | MAGE-like protein 2. (1017 aa) | ||||
TRIM71 | Tripartite motif containing 71. (661 aa) | ||||
H920_13135 | F-box only protein 28. (357 aa) | ||||
RNF34 | E3 ubiquitin-protein ligase RNF34. (373 aa) | ||||
HECTD1 | E3 ubiquitin-protein ligase HECTD1. (2563 aa) | ||||
JADE2 | Protein Jade-2. (825 aa) | ||||
H920_09656 | Catenin beta-1. (83 aa) | ||||
H920_07431 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (136 aa) | ||||
UBE2S | Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (212 aa) | ||||
UBE2V1 | Ubiquitin-conjugating enzyme E2 variant 1. (175 aa) | ||||
ANAPC10 | Anaphase promoting complex subunit 10. (185 aa) | ||||
NFE2L1 | Nuclear factor, erythroid 2 like 1. (648 aa) | ||||
NEDD4L | E3 ubiquitin-protein ligase. (983 aa) | ||||
ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) | ||||
ENSFDAP00000013779 | annotation not available (95 aa) | ||||
Rnf146 | E3 ubiquitin-protein ligase RNF146. (354 aa) | ||||
Rnf187 | E3 ubiquitin-protein ligase RNF187. (124 aa) | ||||
ENSFDAP00000014313 | annotation not available (236 aa) | ||||
MUL1 | Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa) | ||||
SYVN1 | E3 ubiquitin-protein ligase synoviolin. (609 aa) | ||||
ENSFDAP00000014397 | annotation not available (128 aa) | ||||
ENSFDAP00000014465 | annotation not available (393 aa) | ||||
ENSFDAP00000014687 | annotation not available (76 aa) | ||||
RNF19B | RBR-type E3 ubiquitin transferase. (521 aa) | ||||
RNF213 | RING finger protein 213. (5080 aa) | ||||
NEDD4 | E3 ubiquitin-protein ligase. (837 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa) | ||||
H920_20354 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa) | ||||
ENSFDAP00000015759 | annotation not available (147 aa) | ||||
WWP1 | E3 ubiquitin-protein ligase. (918 aa) | ||||
ENSFDAP00000015944 | annotation not available (350 aa) | ||||
Arih2 | RBR-type E3 ubiquitin transferase. (491 aa) | ||||
PELI3 | Pellino E3 ubiquitin protein ligase family member 3. (445 aa) | ||||
UBE2O | Ubiquitin-conjugating enzyme E2 O. (1139 aa) | ||||
RNF114 | RING finger protein 114. (196 aa) | ||||
FBXW7 | F-box/WD repeat-containing protein 7. (708 aa) | ||||
H920_11313 | Anaphase-promoting complex subunit 13. (74 aa) | ||||
SASH1 | SAM and SH3 domain-containing protein 1. (1233 aa) | ||||
UBE2K | Ubiquitin conjugating enzyme E2 K. (179 aa) | ||||
UBE2E2 | Ubiquitin-conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa) | ||||
UBE3C | Ubiquitin-protein ligase E3C. (1060 aa) | ||||
DTL | Denticleless E3 ubiquitin protein ligase homolog. (730 aa) | ||||
ENSFDAP00000017150 | annotation not available (103 aa) | ||||
Fbxl17 | F-box and leucine rich repeat protein 17. (220 aa) | ||||
ERCC8 | DNA excision repair protein ERCC-8. (395 aa) | ||||
H920_09142 | E3 ubiquitin-protein ligase ZFP91. (491 aa) | ||||
UBE2E1 | Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) | ||||
LOC104869977 | Tripartite motif-containing protein 34. (486 aa) | ||||
H920_00962 | Tripartite motif-containing protein 5. (476 aa) | ||||
UBE2E3 | Ubiquitin-conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa) | ||||
DDB2 | DNA damage-binding protein 2. (296 aa) | ||||
ENSFDAP00000017776 | annotation not available (72 aa) | ||||
CDC27 | Cell division cycle 27. (825 aa) | ||||
SMURF1 | E3 ubiquitin-protein ligase SMURF1. (744 aa) | ||||
BARD1 | BRCA1-associated RING domain protein 1. (672 aa) | ||||
H920_15675 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (135 aa) | ||||
MARCHF6 | E3 ubiquitin-protein ligase MARCH6. (903 aa) | ||||
ENSFDAP00000018265 | annotation not available (54 aa) | ||||
RNF183 | RING finger protein 183. (190 aa) | ||||
H920_01229 | Cullin-1; Belongs to the cullin family. (265 aa) | ||||
RNF126 | RING finger protein 126. (288 aa) | ||||
FBXO4 | F-box protein 4. (360 aa) | ||||
ZSWIM2 | E3 ubiquitin-protein ligase ZSWIM2. (631 aa) | ||||
RNF144B | RBR-type E3 ubiquitin transferase. (303 aa) | ||||
PRPF19 | Pre-mRNA-processing factor 19. (440 aa) | ||||
Ctnnb1 | Catenin beta-1. (781 aa) | ||||
Fbxo28 | F-box only protein 28. (163 aa) | ||||
UBE2H | Ubiquitin-conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa) | ||||
TNFAIP3 | Tumor necrosis factor alpha-induced protein 3. (755 aa) | ||||
AKTIP | AKT-interacting protein. (292 aa) | ||||
MARCHF5 | Membrane associated ring-CH-type finger 5. (278 aa) | ||||
RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (559 aa) | ||||
CUL1 | Cullin-1; Belongs to the cullin family. (776 aa) | ||||
TRIM32 | E3 ubiquitin-protein ligase TRIM32. (653 aa) | ||||
TNKS | Poly [ADP-ribose] polymerase. (1327 aa) | ||||
RNF14 | RBR-type E3 ubiquitin transferase. (474 aa) | ||||
RNF111 | E3 ubiquitin-protein ligase Arkadia; Belongs to the cyclin family. (987 aa) | ||||
KLHL20 | Kelch-like protein 20. (609 aa) | ||||
TRIM2 | Tripartite motif-containing protein 2. (764 aa) | ||||
WSB2 | WD repeat and SOCS box-containing protein 2. (406 aa) | ||||
FBXL7 | F-box/LRR-repeat protein 7. (478 aa) | ||||
Amfr | Autocrine motility factor receptor. (98 aa) | ||||
WWP2 | E3 ubiquitin-protein ligase. (870 aa) | ||||
SHARPIN | Sharpin. (414 aa) | ||||
KLHL3 | Kelch-like protein 3. (613 aa) | ||||
PPIL2 | Peptidyl-prolyl cis-trans isomerase-like 2. (520 aa) | ||||
UBE2C | Ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) | ||||
ENSFDAP00000020777 | annotation not available (90 aa) | ||||
UBE2Q1 | Ubiquitin conjugating enzyme E2 Q1. (253 aa) | ||||
UBE2D2 | Ubiquitin-conjugating enzyme E2 D4; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) | ||||
TRIM21 | E3 ubiquitin-protein ligase TRIM21. (467 aa) | ||||
UBE2Q2 | Ubiquitin-conjugating enzyme E2 Q2. (373 aa) | ||||
TRAF3IP2 | Adapter protein CIKS. (546 aa) | ||||
UBE2V2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) | ||||
RNF5 | E3 ubiquitin-protein ligase RNF5. (180 aa) | ||||
AXIN1 | Axin-1. (865 aa) | ||||
SKP1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (188 aa) | ||||
UBE2D4 | Ubiquitin conjugating enzyme E2 D4 (putative). (107 aa) | ||||
WSB1 | WD repeat and SOCS box-containing protein 1. (421 aa) | ||||
Znrf2 | Zinc and ring finger 2. (90 aa) | ||||
FBXO22 | F-box protein 22. (299 aa) | ||||
TRIML1 | Putative E3 ubiquitin-protein ligase TRIML1. (457 aa) | ||||
BIRC2 | Baculoviral IAP repeat-containing protein 2. (618 aa) | ||||
UBE2D1 | Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (140 aa) | ||||
Bfar | Bifunctional apoptosis regulator. (448 aa) | ||||
HACE1 | E3 ubiquitin-protein ligase HACE1. (883 aa) | ||||
TRAF1 | TNF receptor-associated factor. (415 aa) | ||||
FBXW9 | F-box/WD repeat-containing protein 9. (444 aa) | ||||
MGRN1 | E3 ubiquitin-protein ligase MGRN1. (530 aa) | ||||
RBX1 | E3 ubiquitin-protein ligase RBX1. (108 aa) | ||||
ARIH1 | RBR-type E3 ubiquitin transferase. (454 aa) |