STRINGSTRING
LOC104863987 LOC104863987 POLG POLG ATP5F1A ATP5F1A TIMP2 TIMP2 LOC104865150 LOC104865150 ENSFDAP00000014465 ENSFDAP00000014465 ITGAV ITGAV TIMP4 TIMP4 H920_06641 H920_06641 ADRM1 ADRM1 RIOK3 RIOK3 SYVN1 SYVN1 BANK1 BANK1 H920_06640 H920_06640 H920_02645 H920_02645 NTRK2 NTRK2 COMP COMP SELL SELL CFLAR CFLAR TRIP4 TRIP4 Vcp Vcp SERPINC1 SERPINC1 H920_19198 H920_19198 LOC104873657 LOC104873657 Fas Fas H920_06638 H920_06638 PRNP PRNP Tysnd1 Tysnd1 SART3 SART3 LOC104854928 LOC104854928 SLC6A3 SLC6A3 LOC104854954 LOC104854954 CCBE1 CCBE1 KIT KIT STIM1 STIM1 DVL3 DVL3 DERL1 DERL1 SLC2A13 SLC2A13 LOC104863283 LOC104863283 NFRKB NFRKB BIN1 BIN1 FLOT1 FLOT1 RAD23A RAD23A Amfr Amfr CLTCL1 CLTCL1 COL3A1 COL3A1 ATP9A ATP9A H920_05903 H920_05903 CAST CAST Casp8ap2 Casp8ap2 TNFAIP3 TNFAIP3 NDUFS7 NDUFS7 H920_05366 H920_05366 RIPK2 RIPK2 H920_12197 H920_12197 RYR1 RYR1 LOC104861359 LOC104861359 TIMP1 TIMP1 LOC104860847 LOC104860847 PANX1 PANX1 A2M A2M Serpinb3 Serpinb3 ENSFDAP00000018569 ENSFDAP00000018569 Ubc Ubc MARCHF6 MARCHF6 XIAP XIAP F3 F3 ECM1 ECM1 ENSFDAP00000017753 ENSFDAP00000017753 H920_00389 H920_00389 YIPF7 YIPF7 Pycard Pycard ENSFDAP00000017142 ENSFDAP00000017142 SERPINE1 SERPINE1 FBXO45 FBXO45 Psap Psap LOC104868184 LOC104868184 PTEN PTEN CSTB CSTB Itgb3 Itgb3 COL1A1 COL1A1 LOC104876709 LOC104876709 IL1R1 IL1R1 Anxa2 Anxa2 BRCA2 BRCA2 ENSFDAP00000014843 ENSFDAP00000014843 INS INS ITGA3 ITGA3 H920_00388 H920_00388 LRP1 LRP1 FADD FADD Tnfrsf10b Tnfrsf10b TWNK TWNK H920_07458 H920_07458 SELENOS SELENOS Lonp2 Lonp2 SERPINB13 SERPINB13 HSPG2 HSPG2 Muc5b Muc5b SPATA2 SPATA2 TNF TNF Yipf5 Yipf5 LOC104873705 LOC104873705 LOC104865813 LOC104865813 Muc2 Muc2 RNF139 RNF139 FAP FAP SRI SRI OS9 OS9 GSK3B GSK3B COL1A2 COL1A2 TP53 TP53 CDK5R1 CDK5R1 SERPINF2 SERPINF2 RFFL RFFL APC APC FLOT2 FLOT2 BAG6 BAG6 LOC104851075 LOC104851075 SERPINB6 SERPINB6 CD28 CD28 MALT1 MALT1 LCOR LCOR LOC104850731 LOC104850731 ADAMTS4 ADAMTS4 SH3PXD2A SH3PXD2A CLTC CLTC TIMP3 TIMP3 H920_10599 H920_10599 H920_06639 H920_06639 LOC104864168 LOC104864168 ADAMTSL4 ADAMTSL4 ANXA9 ANXA9 FN1 FN1 LOC104861358 LOC104861358 DPP4 DPP4 PINK1 PINK1 PDZD3 PDZD3 Bfar Bfar NOL3 NOL3 SUMO1 SUMO1 ITGB1 ITGB1 FURIN FURIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC104863987Melanoma-associated antigen 4. (380 aa)
POLGDNA polymerase subunit gamma-1. (1219 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
TIMP2Metalloproteinase inhibitor 2. (176 aa)
LOC104865150Melanoma-associated antigen 10. (360 aa)
ENSFDAP00000014465annotation not available (393 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (209 aa)
H920_06641Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (91 aa)
ADRM1Proteasomal ubiquitin receptor ADRM1. (407 aa)
RIOK3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa)
SYVN1E3 ubiquitin-protein ligase synoviolin. (609 aa)
BANK1B-cell scaffold protein with ankyrin repeats. (744 aa)
H920_06640Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (262 aa)
H920_02645Ligand-dependent corepressor. (433 aa)
NTRK2Tyrosine-protein kinase receptor. (833 aa)
COMPCartilage oligomeric matrix protein. (712 aa)
SELLSelectin L. (372 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (435 aa)
TRIP4Activating signal cointegrator 1. (579 aa)
VcpTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (800 aa)
SERPINC1Antithrombin-III; Belongs to the serpin family. (460 aa)
H920_19198Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (229 aa)
LOC104873657mucin-5AC. (2600 aa)
FasTumor necrosis factor receptor superfamily member 6. (290 aa)
H920_06638Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (217 aa)
PRNPMajor prion protein; Belongs to the prion family. (236 aa)
Tysnd1Peroxisomal leader peptide-processing protease. (205 aa)
SART3Squamous cell carcinoma antigen recognized by T-cells 3. (962 aa)
LOC104854928Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (198 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
LOC104854954Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (291 aa)
CCBE1Collagen and calcium-binding EGF domain-containing protein 1. (408 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (955 aa)
STIM1Stromal interaction molecule 1. (801 aa)
DVL3Segment polarity protein dishevelled like protein DVL-3. (606 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
SLC2A13Proton myo-inositol cotransporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (459 aa)
LOC104863283Charged multivesicular body protein 3. (221 aa)
NFRKBNuclear factor related to kappa-B-binding protein. (1299 aa)
BIN1Bridging integrator 1. (556 aa)
FLOT1Flotillin 1. (380 aa)
RAD23AUV excision repair protein RAD23 like protein A. (362 aa)
AmfrAutocrine motility factor receptor. (98 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1263 aa)
COL3A1Collagen alpha-1(III) chain. (1463 aa)
ATP9APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1024 aa)
H920_05903Charged multivesicular body protein 3. (197 aa)
CASTCalpastatin. (824 aa)
Casp8ap2CASP8-associated protein 2. (190 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (755 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7. (214 aa)
H920_05366Kininogen-1. (224 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (482 aa)
H920_12197Mucin-2. (883 aa)
RYR1Ryanodine receptor 1. (4870 aa)
LOC104861359Serpin B9; Belongs to the serpin family. (431 aa)
TIMP1Metalloproteinase inhibitor 1. (207 aa)
LOC104860847Death domain-containing protein CRADD. (199 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa)
A2MAlpha-2-macroglobulin. (1475 aa)
Serpinb3Serpin B3; Belongs to the serpin family. (346 aa)
ENSFDAP00000018569annotation not available (445 aa)
UbcPolyubiquitin-B. (235 aa)
MARCHF6E3 ubiquitin-protein ligase MARCH6. (903 aa)
XIAPBaculoviral IAP repeat-containing protein 4. (497 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (329 aa)
ECM1Extracellular matrix protein 1. (560 aa)
ENSFDAP00000017753annotation not available (63 aa)
H920_00389Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (226 aa)
YIPF7Protein YIPF. (246 aa)
PycardApoptosis-associated speck-like protein containing a CARD. (122 aa)
ENSFDAP00000017142annotation not available (211 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
FBXO45F-box protein 45. (237 aa)
PsapProactivator polypeptide. (128 aa)
LOC104868184Melanoma-associated antigen 8-like. (337 aa)
PTENPhosphatase and tensin homolog. (403 aa)
CSTBCystatin-B; Belongs to the cystatin family. (76 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (761 aa)
COL1A1Collagen alpha-1(I) chain. (1453 aa)
LOC104876709Serpin B3. (389 aa)
IL1R1Interleukin-1 receptor type 1. (583 aa)
Anxa2Annexin. (339 aa)
BRCA2Breast cancer type 2 susceptibility protein. (3134 aa)
ENSFDAP00000014843annotation not available (337 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
ITGA3Integrin alpha-3; Belongs to the integrin alpha chain family. (1000 aa)
H920_00388Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (309 aa)
LRP1Prolow-density lipoprotein receptor-related protein 1. (4419 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
Tnfrsf10bTumor necrosis factor receptor superfamily member 10B. (417 aa)
TWNKTwinkle protein, mitochondrial. (684 aa)
H920_07458Death domain-containing protein CRADD. (199 aa)
SELENOSSelenoprotein S. (190 aa)
Lonp2Lon protease like protein 2, peroxisomal; Belongs to the peptidase S16 family. (432 aa)
SERPINB13Serpin B13; Belongs to the serpin family. (388 aa)
HSPG2Basement membrane-specific heparan sulfate proteoglycan core protein. (4246 aa)
Muc5bMucin-5B. (4256 aa)
SPATA2Spermatogenesis-associated protein 2. (514 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
Yipf5Protein YIPF. (257 aa)
LOC104873705Putative MAGE domain-containing protein MAGEA13P. (409 aa)
LOC104865813Pulmonary surfactant-associated protein A. (240 aa)
Muc2Mucin-2. (476 aa)
RNF139E3 ubiquitin-protein ligase RNF139. (604 aa)
FAPSeprase; Belongs to the peptidase S9B family. (759 aa)
SRISorcin. (183 aa)
OS9Protein OS-9. (668 aa)
GSK3BGlycogen synthase kinase 3 beta. (442 aa)
COL1A2Collagen alpha-2(I) chain. (1366 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
SERPINF2Alpha-2-antiplasmin; Belongs to the serpin family. (427 aa)
RFFLE3 ubiquitin-protein ligase rififylin. (366 aa)
APCAdenomatous polyposis coli protein. (2857 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (412 aa)
BAG6Large proline-rich protein BAG6. (1117 aa)
LOC104851075Cystatin-C; Belongs to the cystatin family. (141 aa)
SERPINB6Serpin B6; Belongs to the serpin family. (378 aa)
CD28T-cell-specific surface glycoprotein CD28. (255 aa)
MALT1Uncharacterized protein. (770 aa)
LCORUncharacterized protein. (1187 aa)
LOC104850731Alpha-1-inhibitor 3-like. (1381 aa)
ADAMTS4A disintegrin and metalloproteinase with thrombospondin motifs 4. (844 aa)
SH3PXD2ASH3 and PX domain-containing protein 2A. (774 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
TIMP3Metalloproteinase inhibitor 3. (211 aa)
H920_10599Titin. (5421 aa)
H920_06639Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (683 aa)
LOC104864168Cathepsin G; Belongs to the peptidase S1 family. (246 aa)
ADAMTSL4ADAMTS like 4. (918 aa)
ANXA9Annexin. (342 aa)
FN1Fibronectin. (2477 aa)
LOC104861358Serpin B9. (375 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (764 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (446 aa)
PDZD3Na(+)/H(+) exchange regulatory cofactor NHE-RF4. (498 aa)
BfarBifunctional apoptosis regulator. (448 aa)
NOL3Nucleolar protein 3. (205 aa)
SUMO1Small ubiquitin-related modifier. (110 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (803 aa)
FURINFurin; Belongs to the peptidase S8 family. (796 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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