STRINGSTRING
VCL VCL LIMK1 LIMK1 PTK2B PTK2B ITGB8 ITGB8 PARVG PARVG H920_19760 H920_19760 THSD1 THSD1 ARL14EP ARL14EP GRB7 GRB7 EVL EVL H920_07400 H920_07400 ENSFDAP00000014712 ENSFDAP00000014712 TNS1 TNS1 H920_00521 H920_00521 Wasf1 Wasf1 PIP5K1C PIP5K1C NEDD9 NEDD9 FLRT2 FLRT2 ILK ILK STARD8 STARD8 Limd1 Limd1 H920_12193 H920_12193 ASAP3 ASAP3 NPHS1 NPHS1 Actb Actb FLRT3 FLRT3 H920_14239 H920_14239 ACTN2 ACTN2 RHOU RHOU PAK1 PAK1 PEAK1 PEAK1 NRP1 NRP1 PARVA PARVA ARHGAP24 ARHGAP24 ITGA1 ITGA1 H920_05210 H920_05210 CASS4 CASS4 IL1RL1 IL1RL1 DIXDC1 DIXDC1 LCP1 LCP1 GIT1 GIT1 CORO2B CORO2B IQGAP1 IQGAP1 SYNPO2 SYNPO2 ITGAV ITGAV INPP5E INPP5E LOC104855160 LOC104855160 PARVB PARVB FES FES GAK GAK ITGB7 ITGB7 TES TES MAP2K1 MAP2K1 TRIP6 TRIP6 Tns3 Tns3 ENSFDAP00000005651 ENSFDAP00000005651 DAG1 DAG1 LPXN LPXN PRUNE1 PRUNE1 Arhgap26 Arhgap26 SORBS2 SORBS2 USP33 USP33 AVIL AVIL LPP LPP TRPV4 TRPV4 DLC1 DLC1 Ajuba Ajuba NEXN NEXN Fblim1 Fblim1 IRF2 IRF2 TADA1 TADA1 PDPK1 PDPK1 RDX RDX Lims1 Lims1 LOC104854732 LOC104854732 BCAR1 BCAR1 PXN PXN ITGB5 ITGB5 FOCAD FOCAD Map2k2 Map2k2 TNS2 TNS2 ALKBH6 ALKBH6 CPNE3 CPNE3 Itgb2 Itgb2 ACTN3 ACTN3 CTTN CTTN REXO2 REXO2 ENAH ENAH TM4SF20 TM4SF20 KEAP1 KEAP1 BCAR3 BCAR3 SLA SLA SDC4 SDC4 CAPN2 CAPN2 Sh3kbp1 Sh3kbp1 SENP1 SENP1 RALA RALA PDLIM7 PDLIM7 SRP68 SRP68 ITGA2 ITGA2 H920_14496 H920_14496 ITGB1 ITGB1 ACTG1 ACTG1 ACTL8 ACTL8 ATAT1 ATAT1 ZNF384 ZNF384 MAP4K4 MAP4K4 ITGB6 ITGB6 GFRAL GFRAL EPHA2 EPHA2 MAPK1 MAPK1 CAV1 CAV1 FERMT1 FERMT1 LIMA1 LIMA1 Pik3r2 Pik3r2 PTPRA PTPRA ARPC2 ARPC2 CAV2 CAV2 SDCBP SDCBP MAPRE1 MAPRE1 MAPK3 MAPK3 PGM5 PGM5 ITGA5 ITGA5 EFS EFS FAM107A FAM107A ITGBL1 ITGBL1 TLN1 TLN1 JAK2 JAK2 FLNB FLNB PTK2 PTK2 H920_19642 H920_19642 PALLD PALLD TNS4 TNS4 PRAG1 PRAG1 RSU1 RSU1 LIMS2 LIMS2 PPFIA1 PPFIA1 MAPRE2 MAPRE2 ITGA11 ITGA11 TLN2 TLN2 LOC104855452 LOC104855452 Itgb3 Itgb3 EPB41L5 EPB41L5 ENSFDAP00000001033 ENSFDAP00000001033 ADGRB1 ADGRB1 PHLDB2 PHLDB2 ARL14EPL ARL14EPL CYBA CYBA ACTN1 ACTN1 ARHGEF7 ARHGEF7 UBOX5 UBOX5 ANXA6 ANXA6 SHROOM4 SHROOM4 SLC6A4 SLC6A4 FERMT2 FERMT2 NOX4 NOX4 SORBS1 SORBS1 ZYX ZYX PTPRC PTPRC ITGB4 ITGB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VCLVinculin. (1138 aa)
LIMK1LIM domain kinase 1. (631 aa)
PTK2BProtein-tyrosine kinase 2-beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (768 aa)
PARVGParvin gamma. (332 aa)
H920_19760Arachidonate 15-lipoxygenase B. (236 aa)
THSD1Thrombospondin type-1 domain-containing protein 1. (854 aa)
ARL14EPARF7EP_C domain-containing protein. (275 aa)
GRB7Growth factor receptor-bound protein 7. (536 aa)
EVLEna/VASP-like protein. (399 aa)
H920_07400Krueppel-like factor 11. (80 aa)
ENSFDAP00000014712annotation not available (471 aa)
TNS1Tensin-1. (1804 aa)
H920_00521Vinexin. (327 aa)
Wasf1Wiskott-Aldrich syndrome protein family member 1. (559 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (649 aa)
NEDD9Enhancer of filamentation 1. (833 aa)
FLRT2Leucine-rich repeat transmembrane protein FLRT2. (660 aa)
ILKIntegrin-linked protein kinase. (452 aa)
STARD8StAR-related lipid transfer protein 8. (1016 aa)
Limd1LIM domains containing 1. (405 aa)
H920_12193Actin, cytoplasmic type 8; Belongs to the actin family. (187 aa)
ASAP3Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3. (836 aa)
NPHS1Nephrin. (1249 aa)
ActbActin, cytoplasmic 1. (375 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3. (648 aa)
H920_14239SH3 domain-containing kinase-binding protein 1. (113 aa)
ACTN2Alpha-actinin-2. (894 aa)
RHOURho-related GTP-binding protein RhoU. (199 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PEAK1Pseudopodium-enriched atypical kinase 1. (1743 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (898 aa)
PARVAAlpha-parvin. (372 aa)
ARHGAP24Rho GTPase-activating protein 24. (749 aa)
ITGA1Integrin subunit alpha 1. (1175 aa)
H920_05210Actin-41; Belongs to the actin family. (193 aa)
CASS4Cas scaffolding protein family member 4. (760 aa)
IL1RL1Interleukin-1 receptor-like 1. (555 aa)
DIXDC1Dixin. (711 aa)
LCP1Plastin-2. (627 aa)
GIT1ARF GTPase-activating protein GIT1. (770 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (475 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1638 aa)
SYNPO2Synaptopodin-2. (1261 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (419 aa)
LOC104855160Rho GTPase-activating protein 26. (451 aa)
PARVBParvin beta. (326 aa)
FESFES proto-oncogene, tyrosine kinase. (822 aa)
GAKCyclin-G-associated kinase. (1288 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (736 aa)
TESTestin. (421 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (388 aa)
TRIP6Thyroid receptor-interacting protein 6. (481 aa)
Tns3Tensin-3. (359 aa)
ENSFDAP00000005651annotation not available (195 aa)
DAG1Dystroglycan. (893 aa)
LPXNLeupaxin. (380 aa)
PRUNE1Protein prune like protein. (446 aa)
Arhgap26Rho GTPase-activating protein 26. (171 aa)
SORBS2Sorbin and SH3 domain-containing protein 2. (1215 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (911 aa)
AVILVillin-1. (819 aa)
LPPLipoma-preferred partner. (613 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
DLC1Rho GTPase-activating protein 7. (1526 aa)
AjubaProtein ajuba. (121 aa)
NEXNNexilin. (674 aa)
Fblim1Filamin-binding LIM protein 1. (298 aa)
IRF2Interferon regulatory factor. (349 aa)
TADA1Transcriptional adapter 1. (310 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (558 aa)
RDXRadixin. (583 aa)
Lims1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (394 aa)
LOC104854732Uncharacterized protein. (472 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1. (870 aa)
PXNPaxillin. (585 aa)
ITGB5Integrin subunit beta 5. (794 aa)
FOCADDUF3730 domain-containing protein. (1797 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (370 aa)
TNS2Tensin-like C1 domain-containing phosphatase. (1396 aa)
ALKBH6Putative alpha-ketoglutarate-dependent dioxygenase ABH6. (238 aa)
CPNE3Copine-3. (533 aa)
Itgb2Integrin beta. (461 aa)
ACTN3Alpha-actinin-3. (900 aa)
CTTNSrc substrate cortactin. (548 aa)
REXO2Oligoribonuclease, mitochondrial. (237 aa)
ENAHENAH actin regulator. (810 aa)
TM4SF20Transmembrane 4 L6 family member 20. (227 aa)
KEAP1Kelch like ECH associated protein 1. (538 aa)
BCAR3Breast cancer anti-estrogen resistance protein 3. (824 aa)
SLASrc like adaptor. (296 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa)
CAPN2Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (597 aa)
Sh3kbp1SH3 domain containing kinase binding protein 1. (709 aa)
SENP1Sentrin-specific protease 1. (636 aa)
RALARas-related protein Ral-A. (206 aa)
PDLIM7PDZ and LIM domain protein 7. (456 aa)
SRP68Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (624 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
H920_14496Nesprin-2. (661 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (803 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (362 aa)
ZNF384Zinc finger protein 384. (563 aa)
MAP4K4TRAF2 and NCK-interacting protein kinase. (1272 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (807 aa)
GFRALGDNF family receptor alpha-like. (396 aa)
EPHA2Ephrin type-A receptor 2. (947 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
FERMT1Fermitin family like protein 1. (677 aa)
LIMA1LIM domain and actin-binding protein 1. (766 aa)
Pik3r2Phosphoinositide-3-kinase regulatory subunit 2. (71 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (799 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
CAV2Caveolin 2. (143 aa)
SDCBPSyntenin-1. (241 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (268 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
PGM5Phosphoglucomutase-like protein 5; Belongs to the phosphohexose mutase family. (493 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (991 aa)
EFSEmbryonal Fyn-associated substrate. (556 aa)
FAM107AProtein FAM107A. (144 aa)
ITGBL1Integrin beta-like protein 1. (473 aa)
TLN1Talin-1. (2541 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
FLNBFilamin-B. (2602 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1083 aa)
H920_19642Vasodilator-stimulated phosphoprotein. (108 aa)
PALLDPalladin. (903 aa)
TNS4Tensin-4. (663 aa)
PRAG1Tyrosine-protein kinase SgK223. (1351 aa)
RSU1Ras suppressor protein 1. (277 aa)
LIMS2LIM zinc finger domain containing 2. (337 aa)
PPFIA1Liprin-alpha-1. (1267 aa)
MAPRE2Microtubule-associated protein RP/EB family member 2. (357 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1188 aa)
TLN2Talin-2. (2542 aa)
LOC104855452Wiskott-Aldrich syndrome protein family member 1. (379 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (761 aa)
EPB41L5Band 4.1-like protein 5. (734 aa)
ENSFDAP00000001033annotation not available (269 aa)
ADGRB1Adhesion G protein-coupled receptor B1. (1425 aa)
PHLDB2Pleckstrin homology-like domain family B member 2. (1340 aa)
ARL14EPLADP ribosylation factor like GTPase 14 effector protein like. (152 aa)
CYBACytochrome b-245 light chain. (170 aa)
ACTN1Alpha-actinin-1. (892 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (809 aa)
UBOX5RING finger protein 37. (541 aa)
ANXA6Annexin. (646 aa)
SHROOM4Protein Shroom4. (1522 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
FERMT2Fermitin family like protein 2. (716 aa)
NOX4NADPH oxidase 4. (559 aa)
SORBS1Sorbin and SH3 domain containing 1. (936 aa)
ZYXZyxin. (534 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C. (1146 aa)
ITGB4Integrin beta. (1761 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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