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UBE2V1 UBE2V1 REV1 REV1 POLH POLH POLI POLI DTL DTL ENSFDAP00000017776 ENSFDAP00000017776 RAD18 RAD18 ENSFDAP00000018569 ENSFDAP00000018569 POLD1 POLD1 Pold3 Pold3 POLN POLN POLE2 POLE2 ZBTB1 ZBTB1 MSH2 MSH2 UBE2V2 UBE2V2 POLD2 POLD2 REV3L REV3L MAD2L2 MAD2L2 Pclaf Pclaf BRCA1 BRCA1 ENSFDAP00000006648 ENSFDAP00000006648 PARP10 PARP10 SPRTN SPRTN PRIMPOL PRIMPOL Vcp Vcp H920_07462 H920_07462 POLDIP2 POLDIP2 NSMCE1 NSMCE1 PCNA PCNA POLK POLK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (175 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1248 aa)
POLHDNA polymerase eta. (709 aa)
POLIDNA polymerase iota. (698 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
ENSFDAP00000017776annotation not available (72 aa)
RAD18E3 ubiquitin-protein ligase RAD18. (501 aa)
ENSFDAP00000018569annotation not available (445 aa)
POLD1DNA polymerase delta 1, catalytic subunit. (933 aa)
Pold3DNA polymerase delta subunit 3. (465 aa)
POLNDNA polymerase nu. (825 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
ZBTB1Zinc finger and BTB domain-containing protein 1. (712 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
POLD2DNA polymerase delta subunit 2. (469 aa)
REV3LDNA polymerase zeta catalytic subunit. (3013 aa)
MAD2L2Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
PclafPCNA clamp associated factor. (70 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1737 aa)
ENSFDAP00000006648annotation not available (129 aa)
PARP10Poly [ADP-ribose] polymerase. (954 aa)
SPRTNUncharacterized protein. (496 aa)
PRIMPOLCoiled-coil domain-containing protein 111. (545 aa)
VcpTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (800 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
POLDIP2Polymerase delta-interacting protein 2. (314 aa)
NSMCE1Non-structural maintenance of chromosomes element 1 like protein. (266 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
POLKDNA polymerase kappa. (862 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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