STRINGSTRING
CSF2 CSF2 CSF1 CSF1 AGT AGT ADIPOQ ADIPOQ Prkch Prkch LPL LPL PLA2G5 PLA2G5 APOB APOB CD36 CD36 H920_19760 H920_19760 ABCA5 ABCA5 ITGAV ITGAV MAPK9 MAPK9 ENSFDAP00000010317 ENSFDAP00000010317 AGTR1 AGTR1 Il18 Il18 NFKBIA NFKBIA Itgb3 Itgb3 PLA2G3 PLA2G3 PPARG PPARG PPARA PPARA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF2Uncharacterized protein. (144 aa)
CSF1Colony stimulating factor 1. (527 aa)
AGTAngiotensinogen; Belongs to the serpin family. (478 aa)
ADIPOQAdiponectin. (246 aa)
PrkchProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
PLA2G5Phospholipase A(2). (138 aa)
APOBApolipoprotein B-100. (4381 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
H920_19760Arachidonate 15-lipoxygenase B. (236 aa)
ABCA5ATP-binding cassette sub-family A member 5. (1638 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ENSFDAP00000010317annotation not available (274 aa)
AGTR1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Il18Interleukin-18. (293 aa)
NFKBIANF-kappa-B inhibitor alpha. (224 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (761 aa)
PLA2G3Group 3 secretory phospholipase A2. (508 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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