22 items (Fukomys damarensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	TTC39B	Tetratricopeptide repeat protein 39B. (604 aa)
	ABHD5	1-acylglycerol-3-phosphate O-acyltransferase ABHD5. (333 aa)
	NR1H3	Oxysterols receptor LXR-alpha. (443 aa)
	TTC39A	Tetratricopeptide repeat protein 39A. (578 aa)
	LEP	Leptin. (167 aa)
	ABCG1	ATP-binding cassette sub-family G member 1. (618 aa)
	LOC104860587	Liver carboxylesterase 22. (314 aa)
	PNPLA2	Patatin-like phospholipase domain-containing protein 2. (429 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (231 aa)
	LOC104860586	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
	LOC104872961	Allergen Fel d 4; Belongs to the calycin superfamily. Lipocalin family. (283 aa)
	ITGAV	Integrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
	LOC104872673	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (545 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (389 aa)
	NR1H2	Oxysterols receptor LXR-beta. (368 aa)
	LOC104848797	Tetratricopeptide repeat protein 39B. (605 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (468 aa)
	OSBPL8	Oxysterol-binding protein; Belongs to the OSBP family. (890 aa)
	PPARD	Peroxisome proliferator-activated receptor delta. (440 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	NFKBIA	NF-kappa-B inhibitor alpha. (224 aa)
	Itgb3	Integrin beta; Belongs to the integrin beta chain family. (761 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG1	NR1H2	ENSFDAP00000014886	ENSFDAP00000018789	ATP-binding cassette sub-family G member 1.	Oxysterols receptor LXR-beta.	0.610
ABCG1	NR1H3	ENSFDAP00000014886	ENSFDAP00000006253	ATP-binding cassette sub-family G member 1.	Oxysterols receptor LXR-alpha.	0.620
ABCG1	PPARG	ENSFDAP00000014886	ENSFDAP00000016315	ATP-binding cassette sub-family G member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.520
ABHD5	PNPLA2	ENSFDAP00000006952	ENSFDAP00000013604	1-acylglycerol-3-phosphate O-acyltransferase ABHD5.	Patatin-like phospholipase domain-containing protein 2.	0.975
ITGAV	Itgb3	ENSFDAP00000007274	ENSFDAP00000016006	Integrin alpha-V; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.998
ITGAV	PTPN2	ENSFDAP00000007274	ENSFDAP00000019428	Integrin alpha-V; Belongs to the integrin alpha chain family.	Tyrosine-protein phosphatase non-receptor type.	0.465
Itgb3	ITGAV	ENSFDAP00000016006	ENSFDAP00000007274	Integrin beta; Belongs to the integrin beta chain family.	Integrin alpha-V; Belongs to the integrin alpha chain family.	0.998
Itgb3	PTPN2	ENSFDAP00000016006	ENSFDAP00000019428	Integrin beta; Belongs to the integrin beta chain family.	Tyrosine-protein phosphatase non-receptor type.	0.498
LEP	PPARA	ENSFDAP00000004609	ENSFDAP00000017793	Leptin.	Peroxisome proliferator activated receptor alpha.	0.525
LEP	PPARG	ENSFDAP00000004609	ENSFDAP00000016315	Leptin.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.646
NFKBIA	PPARG	ENSFDAP00000016040	ENSFDAP00000016315	NF-kappa-B inhibitor alpha.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.436
NR1H2	ABCG1	ENSFDAP00000018789	ENSFDAP00000014886	Oxysterols receptor LXR-beta.	ATP-binding cassette sub-family G member 1.	0.610
NR1H2	NR1H3	ENSFDAP00000018789	ENSFDAP00000006253	Oxysterols receptor LXR-beta.	Oxysterols receptor LXR-alpha.	0.840
NR1H2	PPARA	ENSFDAP00000018789	ENSFDAP00000017793	Oxysterols receptor LXR-beta.	Peroxisome proliferator activated receptor alpha.	0.547
NR1H2	PPARG	ENSFDAP00000018789	ENSFDAP00000016315	Oxysterols receptor LXR-beta.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.521
NR1H3	ABCG1	ENSFDAP00000006253	ENSFDAP00000014886	Oxysterols receptor LXR-alpha.	ATP-binding cassette sub-family G member 1.	0.620
NR1H3	NR1H2	ENSFDAP00000006253	ENSFDAP00000018789	Oxysterols receptor LXR-alpha.	Oxysterols receptor LXR-beta.	0.840
NR1H3	PPARA	ENSFDAP00000006253	ENSFDAP00000017793	Oxysterols receptor LXR-alpha.	Peroxisome proliferator activated receptor alpha.	0.647
NR1H3	PPARG	ENSFDAP00000006253	ENSFDAP00000016315	Oxysterols receptor LXR-alpha.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.637
PNPLA2	ABHD5	ENSFDAP00000013604	ENSFDAP00000006952	Patatin-like phospholipase domain-containing protein 2.	1-acylglycerol-3-phosphate O-acyltransferase ABHD5.	0.975