STRINGSTRING
MEGF10 MEGF10 ROCK1 ROCK1 ITGB1BP1 ITGB1BP1 SIX1 SIX1 CCN3 CCN3 PLEKHO1 PLEKHO1 LOC104876550 LOC104876550 Arpc5 Arpc5 DDIT3 DDIT3 PLAU PLAU ENSFDAP00000021627 ENSFDAP00000021627 DDR1 DDR1 BIN3 BIN3 PDGFRB PDGFRB Itgb3 Itgb3 ABHD2 ABHD2 H920_04111 H920_04111 SEMA6D SEMA6D ENSFDAP00000012198 ENSFDAP00000012198 MET MET PLAT PLAT MSTN MSTN GRB10 GRB10 Akirin1 Akirin1 SMO SMO NET1 NET1 PARVA PARVA THBS4 THBS4 ANXA1 ANXA1 NF1 NF1 ENPP1 ENPP1 AAMP AAMP SIX4 SIX4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEGF10Multiple epidermal growth factor-like domains protein 10. (1149 aa)
ROCK1Rho-associated protein kinase 1; Belongs to the peptidase C19 family. (1368 aa)
ITGB1BP1Integrin beta-1-binding protein 1. (200 aa)
SIX1Homeobox protein SIX1. (284 aa)
CCN3Protein NOV like protein. (271 aa)
PLEKHO1Pleckstrin homology domain-containing family O member 1. (399 aa)
LOC104876550Nascent polypeptide-associated complex subunit alpha, muscle-specific form. (215 aa)
Arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
DDIT3DNA damage-inducible transcript 3 protein. (167 aa)
PLAUUrokinase-type plasminogen activator. (434 aa)
ENSFDAP00000021627annotation not available (136 aa)
DDR1Tyrosine-protein kinase receptor. (916 aa)
BIN3Bridging integrator 3. (253 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1097 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (761 aa)
ABHD2Abhydrolase domain-containing protein 2. (425 aa)
H920_04111Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (130 aa)
SEMA6DSemaphorin-6D; Belongs to the semaphorin family. (1073 aa)
ENSFDAP00000012198annotation not available (156 aa)
METHepatocyte growth factor receptor. (1382 aa)
PLATTissue-type plasminogen activator. (602 aa)
MSTNGrowth/differentiation factor 8. (376 aa)
GRB10Growth factor receptor-bound protein 10. (575 aa)
Akirin1Akirin-1. (198 aa)
SMOSmoothened like protein; Belongs to the G-protein coupled receptor Fz/Smo family. (682 aa)
NET1Neuroepithelial cell-transforming gene 1 protein. (553 aa)
PARVAAlpha-parvin. (372 aa)
THBS4Thrombospondin-4. (901 aa)
ANXA1Annexin A1. (346 aa)
NF1Neurofibromin. (2818 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (873 aa)
AAMPAngio-associated migratory cell protein. (436 aa)
SIX4Homeobox protein SIX4. (592 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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