(71 nodes) SCF ubiquitin ligase complex network (Fukomys damarensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCCRP1	Non-specific cytotoxic cell receptor protein 1 like protein. (267 aa)
	TMEM183A	Transmembrane protein 183. (375 aa)
	BTRC	F-box/WD repeat-containing protein 1A. (589 aa)
	FBXO9	F-box protein 9. (437 aa)
	AMN1	Antagonist of mitotic exit network 1 homolog. (285 aa)
	FBXW11	F-box/WD repeat-containing protein 11. (539 aa)
	FBXW8	F-box/WD repeat-containing protein 8. (585 aa)
	ENSFDAP00000002281	annotation not available (259 aa)
	FBXL2	F-box/LRR-repeat protein 2. (426 aa)
	CCNF	Cyclin-F; Belongs to the cyclin family. (762 aa)
	FBXL3	F-box/LRR-repeat protein 3. (428 aa)
	CUL2	Cullin-2; Belongs to the cullin family. (745 aa)
	SPSB3	SPRY domain-containing SOCS box protein 3. (389 aa)
	SPSB2	SPRY domain-containing SOCS box protein 2. (263 aa)
	FBXL18	F-box/LRR-repeat protein 18. (744 aa)
	Fbxl20	F-box and leucine rich repeat protein 20. (430 aa)
	FBXL16	F-box/LRR-repeat protein 16. (478 aa)
	DAW1	WD repeat-containing protein 69. (415 aa)
	FBXL19	F-box/LRR-repeat protein 19. (617 aa)
	Fbxl15	F-box/LRR-repeat protein 15. (150 aa)
	Fbxl21p	F-box/LRR-repeat protein 21. (460 aa)
	SKP2	S-phase kinase-associated protein 2. (424 aa)
	FBXO17	WD repeat-containing protein 88. (172 aa)
	FBXO15	F-box only protein 15. (550 aa)
	Fbxl8	F-box/LRR-repeat protein 8. (371 aa)
	CKS2	CDC28 protein kinase regulatory subunit 2. (79 aa)
	H920_12355	Bifunctional polynucleotide phosphatase/kinase. (173 aa)
	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1. (201 aa)
	FBXO31	F-box protein 31. (409 aa)
	H920_05040	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (97 aa)
	FBXO7	F-box only protein 7. (477 aa)
	H920_07431	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (136 aa)
	FBXW5	F-box/WD repeat-containing protein 5. (565 aa)
	FBXO42	F-box only protein 42. (720 aa)
	FBXO25	F-box protein 25. (358 aa)
	Fbxo27	F-box only protein 27. (156 aa)
	ENSFDAP00000014287	annotation not available (210 aa)
	FBXL14	F-box and leucine rich repeat protein 14. (335 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	Cacybp	Calcyclin-binding protein. (223 aa)
	H920_20354	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	FBXO33	F-box only protein 33. (430 aa)
	CUL5	Cullin-5; Belongs to the cullin family. (785 aa)
	FBXO48	F-box protein 48. (155 aa)
	FBXW7	F-box/WD repeat-containing protein 7. (708 aa)
	Fbxl17	F-box and leucine rich repeat protein 17. (220 aa)
	FBXO32	F-box only protein 32. (316 aa)
	Fbxl12	F-box/LRR-repeat protein 12. (169 aa)
	Lrrc29	Leucine rich repeat containing 29. (599 aa)
	FBXL6	F-box/LRR-repeat protein 6. (447 aa)
	FBXO39	F-box only protein 39. (443 aa)
	H920_07093	Calcyclin-binding protein. (206 aa)
	H920_15675	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (135 aa)
	H920_01229	Cullin-1; Belongs to the cullin family. (265 aa)
	USP47	Ubiquitin carboxyl-terminal hydrolase 47; Belongs to the peptidase C19 family. (1362 aa)
	FBH1	F-box only protein 18. (1042 aa)
	FBXO4	F-box protein 4. (360 aa)
	FBXL4	F-box/LRR-repeat protein 4. (621 aa)
	Fbxo44	F-box only protein 44. (255 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (776 aa)
	DMAC2	ATP synthase subunit s-like protein. (255 aa)
	FBXL7	F-box/LRR-repeat protein 7. (478 aa)
	LOC104864879	F-box only protein 6. (277 aa)
	FBXO2	F-box only protein 2. (279 aa)
	FBXL5	F-box/LRR-repeat protein 5. (736 aa)
	TRIM21	E3 ubiquitin-protein ligase TRIM21. (467 aa)
	FBXW4	F-box/WD repeat-containing protein 4. (325 aa)
	SKP1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (188 aa)
	SPSB4	SPRY domain-containing SOCS box protein 4. (170 aa)
	FBXL13	F-box/LRR-repeat protein 13. (697 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (108 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMN1	CUL1	ENSFDAP00000001551	ENSFDAP00000020019	Antagonist of mitotic exit network 1 homolog.	Cullin-1; Belongs to the cullin family.	0.635
AMN1	H920_01229	ENSFDAP00000001551	ENSFDAP00000018366	Antagonist of mitotic exit network 1 homolog.	Cullin-1; Belongs to the cullin family.	0.635
AMN1	H920_07431	ENSFDAP00000001551	ENSFDAP00000013050	Antagonist of mitotic exit network 1 homolog.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.680
AMN1	H920_15675	ENSFDAP00000001551	ENSFDAP00000018235	Antagonist of mitotic exit network 1 homolog.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.680
AMN1	H920_20354	ENSFDAP00000001551	ENSFDAP00000015382	Antagonist of mitotic exit network 1 homolog.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.680
AMN1	RBX1	ENSFDAP00000001551	ENSFDAP00000023324	Antagonist of mitotic exit network 1 homolog.	E3 ubiquitin-protein ligase RBX1.	0.678
AMN1	SKP1	ENSFDAP00000001551	ENSFDAP00000022283	Antagonist of mitotic exit network 1 homolog.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.680
AMN1	SKP2	ENSFDAP00000001551	ENSFDAP00000007899	Antagonist of mitotic exit network 1 homolog.	S-phase kinase-associated protein 2.	0.411
BTRC	CCNF	ENSFDAP00000000506	ENSFDAP00000003425	F-box/WD repeat-containing protein 1A.	Cyclin-F; Belongs to the cyclin family.	0.621
BTRC	CUL1	ENSFDAP00000000506	ENSFDAP00000020019	F-box/WD repeat-containing protein 1A.	Cullin-1; Belongs to the cullin family.	0.989
BTRC	CUL2	ENSFDAP00000000506	ENSFDAP00000004386	F-box/WD repeat-containing protein 1A.	Cullin-2; Belongs to the cullin family.	0.500
BTRC	FBXL13	ENSFDAP00000000506	ENSFDAP00000023182	F-box/WD repeat-containing protein 1A.	F-box/LRR-repeat protein 13.	0.430
BTRC	FBXL14	ENSFDAP00000000506	ENSFDAP00000014354	F-box/WD repeat-containing protein 1A.	F-box and leucine rich repeat protein 14.	0.540
BTRC	FBXL3	ENSFDAP00000000506	ENSFDAP00000004310	F-box/WD repeat-containing protein 1A.	F-box/LRR-repeat protein 3.	0.582
BTRC	FBXL4	ENSFDAP00000000506	ENSFDAP00000019340	F-box/WD repeat-containing protein 1A.	F-box/LRR-repeat protein 4.	0.461
BTRC	FBXL6	ENSFDAP00000000506	ENSFDAP00000017949	F-box/WD repeat-containing protein 1A.	F-box/LRR-repeat protein 6.	0.444
BTRC	FBXL7	ENSFDAP00000000506	ENSFDAP00000020314	F-box/WD repeat-containing protein 1A.	F-box/LRR-repeat protein 7.	0.487
BTRC	FBXO17	ENSFDAP00000000506	ENSFDAP00000008370	F-box/WD repeat-containing protein 1A.	WD repeat-containing protein 88.	0.433
BTRC	FBXO2	ENSFDAP00000000506	ENSFDAP00000020934	F-box/WD repeat-containing protein 1A.	F-box only protein 2.	0.895
BTRC	FBXO4	ENSFDAP00000000506	ENSFDAP00000018508	F-box/WD repeat-containing protein 1A.	F-box protein 4.	0.839