(72 nodes) Antigen processing and presentation network (Fukomys damarensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AZGP1	Zinc-alpha-2-glycoprotein; Belongs to the MHC class I family. (309 aa)
	LOC104874226	HLA class II histocompatibility antigen, DQ alpha 1 chain; Belongs to the MHC class II family. (255 aa)
	H920_05759	DLA class II histocompatibility antigen, DR-1 beta chain. (268 aa)
	Fcgr1a	Fc fragment of IgG receptor Ia. (374 aa)
	KDM5D	Lysine-specific demethylase 5D. (1541 aa)
	RAB4A	Ras-related protein Rab-4A. (207 aa)
	HLA-DOA	HLA class II histocompatibility antigen, DO alpha chain; Belongs to the MHC class II family. (289 aa)
	Tap1	Transporter 1, ATP binding cassette subfamily B member. (551 aa)
	RAB35	RAB35, member RAS oncogene family. (183 aa)
	H920_07716	DLA class II histocompatibility antigen, DR-1 beta chain. (137 aa)
	GBA	Glucosylceramidase beta. (516 aa)
	HLA-DOB	HLA class II histocompatibility antigen, DO beta chain. (301 aa)
	ERAP1	Aminopeptidase. (945 aa)
	MARCHF1	E3 ubiquitin-protein ligase MARCH1. (289 aa)
	PDIA3	Protein disulfide-isomerase. (505 aa)
	LOC104850725	C-type lectin domain family 4 member A. (195 aa)
	HLA-DMA	HLA class II histocompatibility antigen, DM alpha chain; Belongs to the MHC class II family. (304 aa)
	H920_06580	HLA class II histocompatibility antigen gamma chain. (148 aa)
	RELB	RELB proto-oncogene, NF-kB subunit. (462 aa)
	ABCB9	ATP binding cassette subfamily B member 9. (757 aa)
	TAPBP	TAP binding protein. (358 aa)
	Treml4	Trem-like transcript 4 protein. (203 aa)
	RAB8B	Ras-related protein Rab-8B. (207 aa)
	AP3D1	AP-3 complex subunit delta-1. (1159 aa)
	Marchf8	E3 ubiquitin-protein ligase MARCH8. (289 aa)
	LOC104850724	C-type lectin domain family 4 member A-like. (244 aa)
	H920_15442	Antigen peptide transporter 2. (750 aa)
	EXT1	Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
	UNC93B1	Protein unc-93 like protein B1. (550 aa)
	IDE	Insulin-degrading enzyme; Belongs to the peptidase M16 family. (995 aa)
	H920_13524	RLA class I histocompatibility antigen, alpha chain 11/11. (331 aa)
	SLC11A1	Natural resistance-associated macrophage protein 1. (548 aa)
	LOC104875717	Patr class I histocompatibility antigen, A-126 alpha chain; Belongs to the MHC class I family. (551 aa)
	RAB3B	Ras-related protein Rab-3B. (219 aa)
	TAPBPL	Tapasin-related protein. (454 aa)
	B2M	Beta-2-microglobulin. (100 aa)
	LOC104874234	H-2 class II histocompatibility antigen, A beta chain. (337 aa)
	CTSE	Cathepsin E; Belongs to the peptidase A1 family. (391 aa)
	Atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (198 aa)
	CD1D	Antigen-presenting glycoprotein CD1d. (326 aa)
	CTSV	Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
	PIKFYVE	1-phosphatidylinositol-3-phosphate 5-kinase. (2097 aa)
	LOC104849006	HLA class II histocompatibility antigen, DM beta chain. (263 aa)
	ENSFDAP00000014313	annotation not available (236 aa)
	CTSS	Golgi phosphoprotein 3-like; Belongs to the peptidase C1 family. (331 aa)
	RAB27A	RAB27A, member RAS oncogene family. (220 aa)
	PSME2	Proteasome activator complex subunit 2. (239 aa)
	RAB10	Ras-related protein Rab-10. (200 aa)
	RAB32	RAB32, member RAS oncogene family. (209 aa)
	RAB5B	Ras-related protein Rab-5B. (215 aa)
	RAB33A	Ras-related protein Rab-33A. (237 aa)
	RAB3C	Ras-related protein Rab-3C. (227 aa)
	PSME1	Proteasome activator complex subunit 1. (249 aa)
	ICAM1	Intercellular adhesion molecule 1. (500 aa)
	CALR	Calreticulin. (417 aa)
	TREX1	Three prime repair exonuclease 1. (314 aa)
	IFI30	Phosphatidylinositol 3-kinase regulatory subunit beta. (202 aa)
	H920_17537	Patr class I histocompatibility antigen, A-126 alpha chain; Belongs to the MHC class I family. (459 aa)
	MFSD6	Major facilitator superfamily domain-containing protein 6. (784 aa)
	ENSFDAP00000017826	annotation not available (133 aa)
	ENSFDAP00000017469	annotation not available (306 aa)
	HLA-DRA	Mamu class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (254 aa)
	LOC104857295	Low affinity immunoglobulin gamma Fc region receptor III-B. (260 aa)
	PSMB9	Proteasome subunit beta type-9. (219 aa)
	MR1	Major histocompatibility complex class I-related gene protein. (338 aa)
	FLT3	FL cytokine receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
	RFTN1	Raftlin. (524 aa)
	WDFY4	WD repeat-and FYVE domain-containing protein 4. (3171 aa)
	ENSFDAP00000007466	annotation not available (44 aa)
	RAB34	Ras-related protein Rab-34. (265 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1084 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB9	AP3D1	ENSFDAP00000004840	ENSFDAP00000003995	ATP binding cassette subfamily B member 9.	AP-3 complex subunit delta-1.	0.402
ABCB9	B2M	ENSFDAP00000004840	ENSFDAP00000003296	ATP binding cassette subfamily B member 9.	Beta-2-microglobulin.	0.586
ABCB9	CALR	ENSFDAP00000004840	ENSFDAP00000018790	ATP binding cassette subfamily B member 9.	Calreticulin.	0.659
ABCB9	H920_13524	ENSFDAP00000004840	ENSFDAP00000002755	ATP binding cassette subfamily B member 9.	RLA class I histocompatibility antigen, alpha chain 11/11.	0.592
ABCB9	H920_15442	ENSFDAP00000004840	ENSFDAP00000003486	ATP binding cassette subfamily B member 9.	Antigen peptide transporter 2.	0.996
ABCB9	H920_17537	ENSFDAP00000004840	ENSFDAP00000018131	ATP binding cassette subfamily B member 9.	Patr class I histocompatibility antigen, A-126 alpha chain; Belongs to the MHC class I family.	0.592
ABCB9	LOC104875717	ENSFDAP00000004840	ENSFDAP00000001593	ATP binding cassette subfamily B member 9.	Patr class I histocompatibility antigen, A-126 alpha chain; Belongs to the MHC class I family.	0.592
ABCB9	MR1	ENSFDAP00000004840	ENSFDAP00000016950	ATP binding cassette subfamily B member 9.	Major histocompatibility complex class I-related gene protein.	0.592
ABCB9	PDIA3	ENSFDAP00000004840	ENSFDAP00000005885	ATP binding cassette subfamily B member 9.	Protein disulfide-isomerase.	0.844
ABCB9	PSMB9	ENSFDAP00000004840	ENSFDAP00000017113	ATP binding cassette subfamily B member 9.	Proteasome subunit beta type-9.	0.904
ABCB9	PSME2	ENSFDAP00000004840	ENSFDAP00000009981	ATP binding cassette subfamily B member 9.	Proteasome activator complex subunit 2.	0.484
ABCB9	TAPBP	ENSFDAP00000004840	ENSFDAP00000004744	ATP binding cassette subfamily B member 9.	TAP binding protein.	0.939
AP3B1	AP3D1	ENSFDAP00000007870	ENSFDAP00000003995	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-3 complex subunit delta-1.	0.998
AP3D1	ABCB9	ENSFDAP00000003995	ENSFDAP00000004840	AP-3 complex subunit delta-1.	ATP binding cassette subfamily B member 9.	0.402
AP3D1	AP3B1	ENSFDAP00000003995	ENSFDAP00000007870	AP-3 complex subunit delta-1.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.998
AP3D1	GBA	ENSFDAP00000003995	ENSFDAP00000007364	AP-3 complex subunit delta-1.	Glucosylceramidase beta.	0.437
AP3D1	H920_13524	ENSFDAP00000003995	ENSFDAP00000002755	AP-3 complex subunit delta-1.	RLA class I histocompatibility antigen, alpha chain 11/11.	0.542
AP3D1	H920_15442	ENSFDAP00000003995	ENSFDAP00000003486	AP-3 complex subunit delta-1.	Antigen peptide transporter 2.	0.402
AP3D1	H920_17537	ENSFDAP00000003995	ENSFDAP00000018131	AP-3 complex subunit delta-1.	Patr class I histocompatibility antigen, A-126 alpha chain; Belongs to the MHC class I family.	0.542
AP3D1	LOC104875717	ENSFDAP00000003995	ENSFDAP00000001593	AP-3 complex subunit delta-1.	Patr class I histocompatibility antigen, A-126 alpha chain; Belongs to the MHC class I family.	0.542