STRINGSTRING
AXL AXL LOC104852000 LOC104852000 WDR54 WDR54 DNM2 DNM2 AAK1 AAK1 PICK1 PICK1 ANKRD13A ANKRD13A PPT1 PPT1 EGF EGF SYT4 SYT4 STX1B STX1B CKAP5 CKAP5 EPHA3 EPHA3 ANKRD13B ANKRD13B PICALM PICALM PCSK9 PCSK9 CALY CALY LRRTM2 LRRTM2 SIRT2 SIRT2 MIB1 MIB1 PPP3CC PPP3CC Insr Insr ARHGAP21 ARHGAP21 TFR2 TFR2 USH1G USH1G VAMP8 VAMP8 HIP1 HIP1 STAP1 STAP1 ACTN4 ACTN4 ROCK1 ROCK1 LGALS3 LGALS3 Hnrnpk Hnrnpk PTPN1 PTPN1 ARFGAP1 ARFGAP1 B2M B2M CBL CBL TSG101 TSG101 HPCAL1 HPCAL1 H920_16947 H920_16947 GATA2 GATA2 DNAJC6 DNAJC6 CD63 CD63 SH3GL2 SH3GL2 DLL1 DLL1 APLN APLN USP46 USP46 EFNB2 EFNB2 HIP1R HIP1R CD36 CD36 EHD4 EHD4 NR1H3 NR1H3 CLIP3 CLIP3 LRRTM1 LRRTM1 PPP3CB PPP3CB NAPB NAPB SYT11 SYT11 PROM2 PROM2 DGKD DGKD ITGAV ITGAV PACSIN2 PACSIN2 SLC17A7 SLC17A7 PARD3 PARD3 AP2A1 AP2A1 LRSAM1 LRSAM1 DTNBP1 DTNBP1 RAB31 RAB31 LOC104862948 LOC104862948 ARRB2 ARRB2 HPCA HPCA NTF3 NTF3 RIT2 RIT2 SH3GL1 SH3GL1 CCL19 CCL19 APOC2 APOC2 SYNJ1 SYNJ1 ENSFDAP00000008900 ENSFDAP00000008900 UNC119 UNC119 CBLL1 CBLL1 KIF3A KIF3A FMR1 FMR1 Fcgr1a Fcgr1a SYNJ2BP SYNJ2BP CLU CLU LRP1 LRP1 ANKRD13D ANKRD13D LRP2 LRP2 BTBD9 BTBD9 MAGI2 MAGI2 SELE SELE LRRC1 LRRC1 ITSN1 ITSN1 LDLRAP1 LDLRAP1 PTPN5 PTPN5 Apela Apela SH3GL3 SH3GL3 TREM2 TREM2 TSC2 TSC2 TNK2 TNK2 SDCBP SDCBP PPP3CA PPP3CA WNT3A WNT3A RAB21 RAB21 OPHN1 OPHN1 DRD2 DRD2 VTN VTN EEF2K EEF2K LRRK2 LRRK2 LOC104860973 LOC104860973 NRG1 NRG1 SYK SYK ANGPT1 ANGPT1 RUFY2 RUFY2 TOR1A TOR1A DNM1L DNM1L SCRIB SCRIB TBC1D5 TBC1D5 NEU3 NEU3 VAMP4 VAMP4 SCYL2 SCYL2 Ap2b1 Ap2b1 CDH13 CDH13 MKLN1 MKLN1 PIP5K1C PIP5K1C DRD3 DRD3 DNM1 DNM1 Anxa2 Anxa2 PLD2 PLD2 NEDD4 NEDD4 Rab5c Rab5c ANO6 ANO6 RAB4A RAB4A GPC3 GPC3 WASL WASL DRD4 DRD4 APPL2 APPL2 SNX12 SNX12 ARC ARC CD22 CD22 MTMR2 MTMR2 MCTP1 MCTP1 ATXN2 ATXN2 ITGA2 ITGA2 CAV3 CAV3 ITGB1 ITGB1 DGKQ DGKQ NCKAP1L NCKAP1L PACSIN3 PACSIN3 AGER AGER STON2 STON2 APOE APOE LRPAP1 LRPAP1 ADD1 ADD1 NUMB NUMB IQSEC1 IQSEC1 BMP2K BMP2K BIN1 BIN1 FLOT1 FLOT1 VPS28 VPS28 RAB5B RAB5B DLG4 DLG4 Ston1 Ston1 CAV1 CAV1 SYT7 SYT7 GSG1L GSG1L CD2AP CD2AP LOC104862775 LOC104862775 SMPD1 SMPD1 H920_10820 H920_10820 CD14 CD14 ADIPOQ ADIPOQ SFRP4 SFRP4 H920_08806 H920_08806 SMAP1 SMAP1 SNAP91 SNAP91 ARRB1 ARRB1 Apoc1 Apoc1 NLGN1 NLGN1 DCX DCX NR1H2 NR1H2 SCAMP5 SCAMP5 DKK1 DKK1 AP2M1 AP2M1 F2RL1 F2RL1 PPP3R1 PPP3R1 BICD1 BICD1 ABCA2 ABCA2 CD151 CD151 DAB2 DAB2 LOC104874513 LOC104874513 APPL1 APPL1 AHI1 AHI1 RSPO1 RSPO1 LOC104857865 LOC104857865 WNT5A WNT5A Rin3 Rin3 SERPINE1 SERPINE1 BCL2L1 BCL2L1 NECAB2 NECAB2 Rab5a Rab5a ENSFDAP00000016887 ENSFDAP00000016887 Atad1 Atad1 NSF NSF ENSFDAP00000016790 ENSFDAP00000016790 Cln3 Cln3 ENSFDAP00000016516 ENSFDAP00000016516 GSG1 GSG1 PPARG PPARG Cdc42 Cdc42 PTEN PTEN SPHK1 SPHK1 Itgb3 Itgb3 SNX33 SNX33 ABCA7 ABCA7 Rab4b Rab4b ANKFY1 ANKFY1 GREM1 GREM1 AMPH AMPH RUFY1 RUFY1 RUBCN RUBCN PACSIN1 PACSIN1 SGIP1 SGIP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AXLTyrosine-protein kinase receptor UFO. (889 aa)
LOC1048520001-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1255 aa)
WDR54WD repeat domain 54. (334 aa)
DNM2Dynamin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (791 aa)
AAK1AP2-associated protein kinase 1. (965 aa)
PICK1PRKCA-binding protein. (414 aa)
ANKRD13AAnkyrin repeat domain-containing protein 13A. (590 aa)
PPT1Palmitoyl-protein thioesterase 1. (306 aa)
EGFPro-epidermal growth factor. (1155 aa)
SYT4Synaptotagmin-4. (425 aa)
STX1BSyntaxin-1B; Belongs to the syntaxin family. (280 aa)
CKAP5Cytoskeleton-associated protein 5. (2031 aa)
EPHA3Ephrin type-A receptor 3. (983 aa)
ANKRD13BAnkyrin repeat domain 13B. (539 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein. (660 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (567 aa)
CALYNeuron-specific vesicular protein calcyon. (269 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (352 aa)
MIB1E3 ubiquitin-protein ligase MIB1. (929 aa)
PPP3CCSerine/threonine-protein phosphatase. (493 aa)
InsrTyrosine-protein kinase receptor. (1345 aa)
ARHGAP21Rho GTPase activating protein 21. (1263 aa)
TFR2Transferrin receptor protein 2. (797 aa)
USH1GUsher syndrome type-1G protein. (459 aa)
VAMP8Vesicle-associated membrane protein 8. (101 aa)
HIP1Huntingtin-interacting protein 1. (989 aa)
STAP1Signal-transducing adaptor protein 1. (291 aa)
ACTN4Alpha-actinin-4. (908 aa)
ROCK1Rho-associated protein kinase 1; Belongs to the peptidase C19 family. (1368 aa)
LGALS3Galectin. (252 aa)
HnrnpkHeterogeneous nuclear ribonucleoprotein K. (464 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (436 aa)
ARFGAP1ADP ribosylation factor GTPase activating protein 1. (427 aa)
B2MBeta-2-microglobulin. (100 aa)
CBLE3 ubiquitin-protein ligase CBL. (851 aa)
TSG101Tumor susceptibility gene 101 protein. (391 aa)
HPCAL1Hippocalcin-like protein 1. (193 aa)
H920_16947Ras-related protein Rab-5A. (205 aa)
GATA2Endothelial transcription factor GATA-2. (480 aa)
DNAJC6Putative tyrosine-protein phosphatase auxilin. (856 aa)
CD63Tetraspanin. (230 aa)
SH3GL2Endophilin-A1. (349 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (671 aa)
APLNApelin. (54 aa)
USP46Ubiquitin carboxyl-terminal hydrolase 46; Belongs to the peptidase C19 family. (366 aa)
EFNB2Ephrin B2. (294 aa)
HIP1RHuntingtin-interacting protein 1-related protein. (1012 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
EHD4EH domain-containing protein 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (479 aa)
NR1H3Oxysterols receptor LXR-alpha. (443 aa)
CLIP3CAP-Gly domain-containing linker protein 3. (547 aa)
LRRTM1Leucine-rich repeat transmembrane neuronal protein 1. (522 aa)
PPP3CBSerine/threonine-protein phosphatase. (499 aa)
NAPBBeta-soluble NSF attachment protein. (298 aa)
SYT11Synaptotagmin-11. (431 aa)
PROM2Prominin-2. (778 aa)
DGKDDiacylglycerol kinase. (1159 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (470 aa)
SLC17A7Vesicular glutamate transporter 1. (539 aa)
PARD3Partitioning defective 3 like protein. (1270 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (976 aa)
LRSAM1E3 ubiquitin-protein ligase LRSAM1. (718 aa)
DTNBP1Dysbindin. (330 aa)
RAB31RAB31, member RAS oncogene family. (183 aa)
LOC104862948Phosphatidylinositol-binding clathrin assembly protein. (406 aa)
ARRB2Beta-arrestin-2. (409 aa)
HPCANeuron-specific calcium-binding protein hippocalcin. (193 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
RIT2GTP-binding protein Rit2. (217 aa)
SH3GL1Endophilin-A2. (340 aa)
CCL19C-C motif chemokine. (104 aa)
APOC2Apolipoprotein C-II. (101 aa)
SYNJ1Synaptojanin-1. (1311 aa)
ENSFDAP00000008900annotation not available (172 aa)
UNC119Protein unc-119 like protein A. (261 aa)
CBLL1E3 ubiquitin-protein ligase Hakai. (491 aa)
KIF3AKinesin family member 3A. (726 aa)
FMR1FMRP translational regulator 1. (622 aa)
Fcgr1aFc fragment of IgG receptor Ia. (374 aa)
SYNJ2BPSynaptojanin-2-binding protein. (146 aa)
CLUClusterin. (444 aa)
LRP1Prolow-density lipoprotein receptor-related protein 1. (4419 aa)
ANKRD13DAnkyrin repeat domain-containing protein 13D. (605 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4630 aa)
BTBD9BTB/POZ domain-containing protein 9. (612 aa)
MAGI2Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (1133 aa)
SELEE-selectin. (617 aa)
LRRC1Leucine-rich repeat-containing protein 1. (471 aa)
ITSN1Intersectin-1. (1716 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (278 aa)
PTPN5Tyrosine-protein phosphatase non-receptor type 5. (541 aa)
ApelaApelin receptor early endogenous ligand. (54 aa)
SH3GL3Endophilin-A3. (312 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (231 aa)
TSC2Tuberin. (1743 aa)
TNK2Activated CDC42 kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1042 aa)
SDCBPSyntenin-1. (241 aa)
PPP3CASerine/threonine-protein phosphatase. (501 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
RAB21RAB21, member RAS oncogene family. (216 aa)
OPHN1Oligophrenin-1. (802 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
VTNVitronectin. (431 aa)
EEF2KEukaryotic elongation factor 2 kinase. (723 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2524 aa)
LOC104860973Low-density lipoprotein receptor-related protein 2. (2025 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform. (699 aa)
SYKTyrosine-protein kinase. (629 aa)
ANGPT1Angiopoietin-1. (416 aa)
RUFY2RUN and FYVE domain containing 2. (604 aa)
TOR1AUncharacterized protein. (272 aa)
DNM1LDynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (736 aa)
SCRIBScribble planar cell polarity protein. (1614 aa)
TBC1D5TBC1 domain family member 5. (801 aa)
NEU3Sialidase-3. (437 aa)
VAMP4Vesicle-associated membrane protein 4. (141 aa)
SCYL2SCY1-like protein 2. (932 aa)
Ap2b1AP complex subunit beta. (951 aa)
CDH13Cadherin-13. (713 aa)
MKLN1Muskelin. (724 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (649 aa)
DRD3D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (447 aa)
DNM1Dynamin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (738 aa)
Anxa2Annexin. (339 aa)
PLD2Phospholipase D2. (936 aa)
NEDD4E3 ubiquitin-protein ligase. (837 aa)
Rab5cRAB5C, member RAS oncogene family. (216 aa)
ANO6Anoctamin. (910 aa)
RAB4ARas-related protein Rab-4A. (207 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (579 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (504 aa)
DRD4Dopamine receptor D4. (302 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (644 aa)
SNX12Sorting nexin-12. (161 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
CD22B-cell receptor CD22. (843 aa)
MTMR2Myotubularin-related protein 2. (643 aa)
MCTP1Multiple C2 and transmembrane domain-containing protein 1. (777 aa)
ATXN2Ataxin-2. (1071 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (803 aa)
DGKQDiacylglycerol kinase. (849 aa)
NCKAP1LNck-associated protein 1-like. (1133 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons protein 3. (423 aa)
AGERAdvanced glycosylation end product-specific receptor. (418 aa)
STON2Stonin-2; Belongs to the Stoned B family. (894 aa)
APOEApolipoprotein E. (228 aa)
LRPAP1Alpha-2-macroglobulin receptor-associated protein. (290 aa)
ADD1Alpha-adducin. (730 aa)
NUMBNUMB endocytic adaptor protein. (649 aa)
IQSEC1IQ motif and SEC7 domain-containing protein 1. (925 aa)
BMP2KBMP-2-inducible protein kinase. (1074 aa)
BIN1Bridging integrator 1. (556 aa)
FLOT1Flotillin 1. (380 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
RAB5BRas-related protein Rab-5B. (215 aa)
DLG4Disks large like protein 4; Belongs to the MAGUK family. (767 aa)
Ston1Stonin-1; Belongs to the Stoned B family. (753 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SYT7Synaptotagmin-7. (556 aa)
GSG1LGerm cell-specific gene 1-like protein. (271 aa)
CD2APCD2-associated protein. (636 aa)
LOC104862775Rab5 GDP/GTP exchange factor. (491 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
H920_10820Heterogeneous nuclear ribonucleoprotein K. (393 aa)
CD14Monocyte differentiation antigen CD14. (383 aa)
ADIPOQAdiponectin. (246 aa)
SFRP4Secreted frizzled-related protein 4. (316 aa)
H920_08806CD63 antigen; Belongs to the tetraspanin (TM4SF) family. (150 aa)
SMAP1Stromal membrane-associated protein 1. (399 aa)
SNAP91Clathrin coat assembly protein AP180. (906 aa)
ARRB1Beta-arrestin-1. (418 aa)
Apoc1Apolipoprotein C-I. (68 aa)
NLGN1Neuroligin-1. (843 aa)
DCXAT-rich interactive domain-containing protein 4A. (365 aa)
NR1H2Oxysterols receptor LXR-beta. (368 aa)
SCAMP5Secretory carrier-associated membrane protein. (235 aa)
DKK1Dickkopf-related protein 1. (268 aa)
AP2M1AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (435 aa)
F2RL1Proteinase-activated receptor 2. (370 aa)
PPP3R1Calcineurin subunit B type 1. (164 aa)
BICD1Protein bicaudal D like protein 1. (973 aa)
ABCA2ATP-binding cassette sub-family A member 2. (2405 aa)
CD151Tetraspanin. (202 aa)
DAB2Disabled like protein 2. (769 aa)
LOC104874513Battenin. (75 aa)
APPL1DCC-interacting protein 13-alpha. (690 aa)
AHI1Jouberin. (1158 aa)
RSPO1R-spondin-1. (266 aa)
LOC104857865Insulin receptor. (222 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
Rin3Ras and Rab interactor 3. (858 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
BCL2L1Bcl-2-like protein 1. (233 aa)
NECAB2Oxidative stress-induced growth inhibitor 1. (320 aa)
Rab5aRas-related protein Rab-5A. (215 aa)
ENSFDAP00000016887annotation not available (781 aa)
Atad1ATPase family AAA domain-containing protein 1. (361 aa)
NSFVesicle-fusing ATPase; Belongs to the AAA ATPase family. (756 aa)
ENSFDAP00000016790annotation not available (357 aa)
Cln3Battenin. (442 aa)
ENSFDAP00000016516annotation not available (156 aa)
GSG1Germ cell-specific gene 1 protein. (366 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
Cdc42Cell division control protein 42 like protein. (191 aa)
PTENPhosphatase and tensin homolog. (403 aa)
SPHK1Sphingosine kinase 1. (406 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (761 aa)
SNX33Sorting nexin. (571 aa)
ABCA7ATP-binding cassette sub-family A member 7. (1989 aa)
Rab4bRas-related protein Rab-4B. (215 aa)
ANKFY1Ankyrin repeat and FYVE domain-containing protein 1. (1169 aa)
GREM1Gremlin-1. (184 aa)
AMPHAmphiphysin. (647 aa)
RUFY1RUN and FYVE domain-containing protein 1. (652 aa)
RUBCNRun domain Beclin-1 interacting and cystein-rich containing protein. (955 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons protein 1. (368 aa)
SGIP1SH3-containing GRB2-like protein 3-interacting protein 1. (828 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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