(78 nodes) Clathrin binding network (Fukomys damarensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYT8	Synaptotagmin-8. (387 aa)
	Ap2b1	AP complex subunit beta. (951 aa)
	DNM1L	Dynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (736 aa)
	AP1S2	Adaptor related protein complex 1 subunit sigma 2. (160 aa)
	SYT13	Synaptotagmin-13. (426 aa)
	AP1S3	Adaptor related protein complex 1 subunit sigma 3. (153 aa)
	LRRK2	Leucine-rich repeat serine/threonine-protein kinase 2. (2524 aa)
	CLTB	Clathrin light chain B. (211 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	LDLRAP1	Low density lipoprotein receptor adapter protein 1. (278 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (185 aa)
	GPR107	Protein GPR107. (506 aa)
	H920_13902	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (181 aa)
	ARMC9	LisH domain-containing protein ARMC9. (605 aa)
	ARRB1	Beta-arrestin-1. (418 aa)
	SNAP91	Clathrin coat assembly protein AP180. (906 aa)
	SMAP1	Stromal membrane-associated protein 1. (399 aa)
	TOM1L2	TOM1-like protein 2; Belongs to the TOM1 family. (528 aa)
	SYT7	Synaptotagmin-7. (556 aa)
	CLBA1	Clathrin binding box of aftiphilin containing 1. (322 aa)
	Ston1	Stonin-1; Belongs to the Stoned B family. (753 aa)
	CLTCL1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1263 aa)
	TEPSIN	ENTH domain-containing protein. (548 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
	AP1M2	AP-1 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family. (409 aa)
	H920_03666	Epsin-3. (316 aa)
	BCL2L1	Bcl-2-like protein 1. (233 aa)
	SYT10	Synaptotagmin-10. (472 aa)
	DAB2	Disabled like protein 2. (769 aa)
	ENSFDAP00000018215	annotation not available (124 aa)
	AP2M1	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (435 aa)
	LMBRD1	Putative lysosomal cobalamin transporter. (467 aa)
	PIK3C2A	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha; Belongs to the PI3/PI4-kinase family. (1685 aa)
	ENTHD1	ENTH domain-containing protein 1. (597 aa)
	TRPC5	Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (972 aa)
	LRP1	Prolow-density lipoprotein receptor-related protein 1. (4419 aa)
	DNER	Delta/notch like EGF repeat containing. (641 aa)
	SYT5	Synaptotagmin 5. (337 aa)
	SCLT1	Sodium channel and clathrin linker 1. (670 aa)
	SYT12	Synaptotagmin-12. (421 aa)
	SYT2	Synaptotagmin-2. (423 aa)
	TOM1	Target of Myb protein 1. (492 aa)
	LOC104862948	Phosphatidylinositol-binding clathrin assembly protein. (406 aa)
	AP1B1	AP-1 complex subunit beta-1. (912 aa)
	EPN2	Epsin-2. (646 aa)
	CLHC1	TSNAXIP1_N domain-containing protein. (591 aa)
	AP2A1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (976 aa)
	GPR108	Protein GPR108. (557 aa)
	SYT9	Synaptotagmin-9. (442 aa)
	SYT11	Synaptotagmin-11. (431 aa)
	SYT17	Synaptotagmin-17. (413 aa)
	GAK	Cyclin-G-associated kinase. (1288 aa)
	NCALD	Neurocalcin-delta. (193 aa)
	SYT3	Leucine-rich repeat-containing protein 4B. (551 aa)
	HIP1R	Huntingtin-interacting protein 1-related protein. (1012 aa)
	TRPC6	Short transient receptor potential channel 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
	SYT1	Synaptotagmin-1. (422 aa)
	NSG2	Neuron-specific protein family member 2. (171 aa)
	DNAJC6	Putative tyrosine-protein phosphatase auxilin. (856 aa)
	AP4B1	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
	AP1G2	AP-1 complex subunit gamma. (778 aa)
	AP1S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (178 aa)
	HIP1	Huntingtin-interacting protein 1. (989 aa)
	Epn1	Epsin 1. (54 aa)
	CEMIP	Protein KIAA1199. (1363 aa)
	Aftph	Aftiphilin. (918 aa)
	AP1G1	AP-1 complex subunit gamma. (825 aa)
	CLINT1	Clathrin interactor 1. (624 aa)
	CALY	Neuron-specific vesicular protein calcyon. (269 aa)
	PICALM	Phosphatidylinositol-binding clathrin assembly protein. (660 aa)
	SYT4	Synaptotagmin-4. (425 aa)
	H920_03683	TOM1-like protein 1. (209 aa)
	ENSFDAP00000016887	annotation not available (781 aa)
	STON2	Stonin-2; Belongs to the Stoned B family. (894 aa)
	Tom1l1	Target of myb1 like 1 membrane trafficking protein. (228 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (928 aa)
	NSG1	Zinc finger and BTB domain-containing protein 49. (191 aa)
	SYT6	Synaptotagmin-6. (525 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1B1	AP1G1	ENSFDAP00000007742	ENSFDAP00000001772	AP-1 complex subunit beta-1.	AP-1 complex subunit gamma.	0.997
AP1B1	AP1G2	ENSFDAP00000007742	ENSFDAP00000002896	AP-1 complex subunit beta-1.	AP-1 complex subunit gamma.	0.996
AP1B1	AP1M2	ENSFDAP00000007742	ENSFDAP00000016949	AP-1 complex subunit beta-1.	AP-1 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family.	0.995
AP1B1	AP1S1	ENSFDAP00000007742	ENSFDAP00000002744	AP-1 complex subunit beta-1.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.995
AP1B1	AP1S2	ENSFDAP00000007742	ENSFDAP00000012840	AP-1 complex subunit beta-1.	Adaptor related protein complex 1 subunit sigma 2.	0.986
AP1B1	AP1S3	ENSFDAP00000007742	ENSFDAP00000012719	AP-1 complex subunit beta-1.	Adaptor related protein complex 1 subunit sigma 3.	0.993
AP1B1	AP2A1	ENSFDAP00000007742	ENSFDAP00000007595	AP-1 complex subunit beta-1.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.979
AP1B1	AP2A2	ENSFDAP00000007742	ENSFDAP00000021494	AP-1 complex subunit beta-1.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.977
AP1B1	AP2M1	ENSFDAP00000007742	ENSFDAP00000018487	AP-1 complex subunit beta-1.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.988
AP1B1	AP2S1	ENSFDAP00000007742	ENSFDAP00000010366	AP-1 complex subunit beta-1.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.982
AP1B1	AP4B1	ENSFDAP00000007742	ENSFDAP00000003742	AP-1 complex subunit beta-1.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.703
AP1B1	ARRB1	ENSFDAP00000007742	ENSFDAP00000019119	AP-1 complex subunit beta-1.	Beta-arrestin-1.	0.704
AP1B1	Aftph	ENSFDAP00000007742	ENSFDAP00000001954	AP-1 complex subunit beta-1.	Aftiphilin.	0.536
AP1B1	Ap2b1	ENSFDAP00000007742	ENSFDAP00000014198	AP-1 complex subunit beta-1.	AP complex subunit beta.	0.589
AP1B1	CLHC1	ENSFDAP00000007742	ENSFDAP00000007663	AP-1 complex subunit beta-1.	TSNAXIP1_N domain-containing protein.	0.863
AP1B1	CLINT1	ENSFDAP00000007742	ENSFDAP00000001410	AP-1 complex subunit beta-1.	Clathrin interactor 1.	0.812
AP1B1	CLTA	ENSFDAP00000007742	ENSFDAP00000021191	AP-1 complex subunit beta-1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.896
AP1B1	CLTB	ENSFDAP00000007742	ENSFDAP00000011488	AP-1 complex subunit beta-1.	Clathrin light chain B.	0.834
AP1B1	CLTC	ENSFDAP00000007742	ENSFDAP00000011129	AP-1 complex subunit beta-1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.928
AP1B1	CLTCL1	ENSFDAP00000007742	ENSFDAP00000020323	AP-1 complex subunit beta-1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.928