STRINGSTRING
NUMA1 NUMA1 VWC2L VWC2L GPC3 GPC3 SOSTDC1 SOSTDC1 SULF1 SULF1 HTRA3 HTRA3 DLX1 DLX1 ENSFDAP00000022428 ENSFDAP00000022428 CDH5 CDH5 CRIM1 CRIM1 SKIL SKIL TWSG1 TWSG1 BMPR2 BMPR2 SMAD4 SMAD4 NBL1 NBL1 LEMD2 LEMD2 CTDSPL2 CTDSPL2 KDR KDR BMP4 BMP4 RGMA RGMA SFRP4 SFRP4 HTRA1 HTRA1 SFRP2 SFRP2 DKK1 DKK1 HJV HJV SMURF1 SMURF1 KCP KCP GDF2 GDF2 WNT5A WNT5A TRIM33 TRIM33 Gata4 Gata4 DAND5 DAND5 PPARG PPARG UBE2O UBE2O GREM1 GREM1 CHRDL2 CHRDL2 GREM2 GREM2 SMAD2 SMAD2 TGFBR3 TGFBR3 SCUBE3 SCUBE3 ENG ENG PELO PELO SFRP5 SFRP5 Nanog Nanog ILK ILK FSTL3 FSTL3 TNFAIP6 TNFAIP6 LOC104860973 LOC104860973 NEO1 NEO1 SKOR1 SKOR1 KIAA1324L KIAA1324L ITGA3 ITGA3 LRP2 LRP2 GDF5 GDF5 Spart Spart SMAD7 SMAD7 CCN1 CCN1 WNT1 WNT1 SKOR2 SKOR2 TCF7L2 TCF7L2 RNF165 RNF165 FSTL1 FSTL1 BMPER BMPER Fbxl15 Fbxl15 CER1 CER1 MSX2 MSX2 SMURF2 SMURF2 CHRDL1 CHRDL1 SFRP1 SFRP1 RBPJ RBPJ FZD1 FZD1 TBX20 TBX20 SKI SKI NOTCH2 NOTCH2 FST FST LEMD3 LEMD3 ACVRL1 ACVRL1 SORL1 SORL1 BAMBI BAMBI ZNF423 ZNF423 TFAP2B TFAP2B CHRD CHRD CRB2 CRB2 HES1 HES1 H920_07050 H920_07050 FKBP8 FKBP8 PPM1A PPM1A FBN1 FBN1 TMPRSS6 TMPRSS6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUMA1Nuclear mitotic apparatus protein 1. (2117 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like. (222 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (579 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
HTRA3Putative serine protease HTRA3. (401 aa)
DLX1Homeobox protein DLX-1. (255 aa)
ENSFDAP00000022428annotation not available (587 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (777 aa)
CRIM1Cysteine-rich motor neuron 1 protein. (926 aa)
SKILSki-like protein. (679 aa)
TWSG1Twisted gastrulation protein like protein 1. (223 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1025 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1. (176 aa)
LEMD2LEM domain-containing protein 2. (271 aa)
CTDSPL2CTD small phosphatase-like protein 2. (466 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1346 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
RGMARepulsive guidance molecule A. (340 aa)
SFRP4Secreted frizzled-related protein 4. (316 aa)
HTRA1Serine protease HTRA1. (391 aa)
SFRP2Secreted frizzled-related protein 2. (286 aa)
DKK1Dickkopf-related protein 1. (268 aa)
HJVHemojuvelin BMP co-receptor. (338 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (744 aa)
KCPKielin cysteine rich BMP regulator. (1467 aa)
GDF2Bone morphogenetic protein 3B. (417 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
TRIM33E3 ubiquitin-protein ligase TRIM33. (951 aa)
Gata4Transcription factor GATA-4. (215 aa)
DAND5DAN domain family member 5. (187 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
UBE2OUbiquitin-conjugating enzyme E2 O. (1139 aa)
GREM1Gremlin-1. (184 aa)
CHRDL2Chordin-like protein 2. (431 aa)
GREM2Gremlin. (168 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TGFBR3Transforming growth factor beta receptor type 3. (850 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 3. (964 aa)
ENGEndoglin. (557 aa)
PELOProtein pelota like protein. (321 aa)
SFRP5Secreted frizzled-related protein 5. (301 aa)
NanogHomeobox protein NANOG. (224 aa)
ILKIntegrin-linked protein kinase. (452 aa)
FSTL3Follistatin-related protein 3. (226 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
LOC104860973Low-density lipoprotein receptor-related protein 2. (2025 aa)
NEO1Neogenin. (1440 aa)
SKOR1SKI family transcriptional corepressor 1. (642 aa)
KIAA1324LUPF0577 protein KIAA1324-like. (954 aa)
ITGA3Integrin alpha-3; Belongs to the integrin alpha chain family. (1000 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4630 aa)
GDF5Growth differentiation factor 5. (495 aa)
SpartSpartin. (665 aa)
SMAD7Mothers against decapentaplegic homolog. (229 aa)
CCN1Protein CYR61. (381 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa)
SKOR2SKI family transcriptional corepressor 2. (578 aa)
TCF7L2Transcription factor 7 like 2. (413 aa)
RNF165RING finger protein 165. (333 aa)
FSTL1Follistatin-related protein 1. (287 aa)
BMPERBMP-binding endothelial regulator protein. (670 aa)
Fbxl15F-box/LRR-repeat protein 15. (150 aa)
CER1Cerberus. (267 aa)
MSX2Homeobox protein MSX-2. (268 aa)
SMURF2E3 ubiquitin-protein ligase. (742 aa)
CHRDL1Chordin-like protein 1. (452 aa)
SFRP1Secreted frizzled-related protein 1. (285 aa)
RBPJRecombining binding protein suppressor of hairless. (526 aa)
FZD1Frizzled class receptor 1. (486 aa)
TBX20T-box transcription factor 20. (404 aa)
SKISki oncogene. (704 aa)
NOTCH2Uncharacterized protein. (2418 aa)
FSTFollistatin. (344 aa)
LEMD3LEM domain containing 3. (781 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
SORL1Sortilin-related receptor. (2119 aa)
BAMBIBMP and activin membrane-bound inhibitor like protein. (235 aa)
ZNF423Zinc finger protein 423. (1314 aa)
TFAP2BTranscription factor AP-2-beta. (460 aa)
CHRDChordin. (862 aa)
CRB2Crumbs like protein 2. (998 aa)
HES1Transcription factor HES-1. (278 aa)
H920_07050Homeobox protein Hox-A13. (191 aa)
FKBP8Peptidylprolyl isomerase. (398 aa)
PPM1AProtein phosphatase 1A; Belongs to the PP2C family. (382 aa)
FBN1Fibrillin-1. (2819 aa)
TMPRSS6Transmembrane protease serine 6; Belongs to the peptidase S1 family. (797 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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