13 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GATA1	Erythroid transcription factor. (413 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1645 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	HPSE	Heparanase. (522 aa)
	Itgb3	Integrin beta; Belongs to the integrin beta chain family. (761 aa)
	GSK3B	Glycogen synthase kinase 3 beta. (442 aa)
	SOX8	Transcription factor SOX-8. (390 aa)
	LTF	Lactotransferrin; Belongs to the transferrin family. (715 aa)
	CCN1	Protein CYR61. (381 aa)
	ITGAV	Integrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
	FBLN5	Fibulin-5. (448 aa)
	IGF1R	Insulin like growth factor 1 receptor. (1107 aa)
	CTHRC1	Collagen triple helix repeat-containing protein 1. (252 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	GATA1	ENSFDAP00000001763	ENSFDAP00000003668	Bone morphogenetic protein 2.	Erythroid transcription factor.	0.544
BMP2	GSK3B	ENSFDAP00000001763	ENSFDAP00000012099	Bone morphogenetic protein 2.	Glycogen synthase kinase 3 beta.	0.442
BMP2	IGF1R	ENSFDAP00000001763	ENSFDAP00000005899	Bone morphogenetic protein 2.	Insulin like growth factor 1 receptor.	0.510
BMP2	Itgb3	ENSFDAP00000001763	ENSFDAP00000016006	Bone morphogenetic protein 2.	Integrin beta; Belongs to the integrin beta chain family.	0.472
GATA1	BMP2	ENSFDAP00000003668	ENSFDAP00000001763	Erythroid transcription factor.	Bone morphogenetic protein 2.	0.544
GATA1	SOX8	ENSFDAP00000003668	ENSFDAP00000011521	Erythroid transcription factor.	Transcription factor SOX-8.	0.456
GSK3B	BMP2	ENSFDAP00000012099	ENSFDAP00000001763	Glycogen synthase kinase 3 beta.	Bone morphogenetic protein 2.	0.442
GSK3B	LRP5	ENSFDAP00000012099	ENSFDAP00000001017	Glycogen synthase kinase 3 beta.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.856
IGF1R	BMP2	ENSFDAP00000005899	ENSFDAP00000001763	Insulin like growth factor 1 receptor.	Bone morphogenetic protein 2.	0.510
IGF1R	LRP5	ENSFDAP00000005899	ENSFDAP00000001017	Insulin like growth factor 1 receptor.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.438
ITGAV	Itgb3	ENSFDAP00000007274	ENSFDAP00000016006	Integrin alpha-V; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.998
Itgb3	BMP2	ENSFDAP00000016006	ENSFDAP00000001763	Integrin beta; Belongs to the integrin beta chain family.	Bone morphogenetic protein 2.	0.472
Itgb3	ITGAV	ENSFDAP00000016006	ENSFDAP00000007274	Integrin beta; Belongs to the integrin beta chain family.	Integrin alpha-V; Belongs to the integrin alpha chain family.	0.998
LRP5	GSK3B	ENSFDAP00000001017	ENSFDAP00000012099	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Glycogen synthase kinase 3 beta.	0.856
LRP5	IGF1R	ENSFDAP00000001017	ENSFDAP00000005899	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Insulin like growth factor 1 receptor.	0.438
SOX8	GATA1	ENSFDAP00000011521	ENSFDAP00000003668	Transcription factor SOX-8.	Erythroid transcription factor.	0.456