(6 nodes) Negative stranded viral RNA replication network (Fukomys damarensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSFDAP00000007466	annotation not available (44 aa)
	ENSFDAP00000017826	annotation not available (133 aa)
	Atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (198 aa)
	ATG16L1	Autophagy-related protein 16-1. (624 aa)
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (699 aa)
	ATG16L2	Autophagy-related protein 16-2. (624 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG16L1	ATG16L2	ENSFDAP00000009391	ENSFDAP00000003914	Autophagy-related protein 16-1.	Autophagy-related protein 16-2.	0.861
ATG16L1	ATG7	ENSFDAP00000009391	ENSFDAP00000008688	Autophagy-related protein 16-1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.876
ATG16L1	Atg5	ENSFDAP00000009391	ENSFDAP00000013584	Autophagy-related protein 16-1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.990
ATG16L1	ENSFDAP00000007466	ENSFDAP00000009391	ENSFDAP00000007466	Autophagy-related protein 16-1.	annotation not available	0.990
ATG16L1	ENSFDAP00000017826	ENSFDAP00000009391	ENSFDAP00000017826	Autophagy-related protein 16-1.	annotation not available	0.990
ATG16L2	ATG16L1	ENSFDAP00000003914	ENSFDAP00000009391	Autophagy-related protein 16-2.	Autophagy-related protein 16-1.	0.861
ATG16L2	ATG7	ENSFDAP00000003914	ENSFDAP00000008688	Autophagy-related protein 16-2.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.837
ATG16L2	Atg5	ENSFDAP00000003914	ENSFDAP00000013584	Autophagy-related protein 16-2.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.974
ATG16L2	ENSFDAP00000007466	ENSFDAP00000003914	ENSFDAP00000007466	Autophagy-related protein 16-2.	annotation not available	0.974
ATG16L2	ENSFDAP00000017826	ENSFDAP00000003914	ENSFDAP00000017826	Autophagy-related protein 16-2.	annotation not available	0.974
ATG7	ATG16L1	ENSFDAP00000008688	ENSFDAP00000009391	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy-related protein 16-1.	0.876
ATG7	ATG16L2	ENSFDAP00000008688	ENSFDAP00000003914	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy-related protein 16-2.	0.837
ATG7	Atg5	ENSFDAP00000008688	ENSFDAP00000013584	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy protein 5; Involved in autophagic vesicle formation.	0.960
ATG7	ENSFDAP00000007466	ENSFDAP00000008688	ENSFDAP00000007466	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	annotation not available	0.960
ATG7	ENSFDAP00000017826	ENSFDAP00000008688	ENSFDAP00000017826	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	annotation not available	0.960
Atg5	ATG16L1	ENSFDAP00000013584	ENSFDAP00000009391	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 16-1.	0.990
Atg5	ATG16L2	ENSFDAP00000013584	ENSFDAP00000003914	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 16-2.	0.974
Atg5	ATG7	ENSFDAP00000013584	ENSFDAP00000008688	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.960
Atg5	ENSFDAP00000017826	ENSFDAP00000013584	ENSFDAP00000017826	Autophagy protein 5; Involved in autophagic vesicle formation.	annotation not available	0.895
ENSFDAP00000007466	ATG16L1	ENSFDAP00000007466	ENSFDAP00000009391	annotation not available	Autophagy-related protein 16-1.	0.990