STRINGSTRING
RFWD3 RFWD3 Tonsl Tonsl Cenpx Cenpx MRE11 MRE11 WRN WRN MCM9 MCM9 POLD1 POLD1 FANCM FANCM NUCKS1 NUCKS1 EXD2 EXD2 BOD1L1 BOD1L1 FBH1 FBH1 H920_12726 H920_12726 DONSON DONSON SMARCAL1 SMARCAL1 BRCA2 BRCA2 DDX11 DDX11 Cenps Cenps ALYREF ALYREF Rtel1 Rtel1 EME1 EME1 TRAIP TRAIP ETAA1 ETAA1 SAMHD1 SAMHD1 CDK9 CDK9 LOC104851526 LOC104851526 THOC1 THOC1 FAM111A FAM111A ATR ATR H920_13460 H920_13460 GEN1 GEN1 EME2 EME2 POLE POLE MUS81 MUS81 MMS22L MMS22L TIMELESS TIMELESS PRIMPOL PRIMPOL ATRX ATRX RAD51 RAD51 BLM BLM ZRANB3 ZRANB3 DNA2 DNA2 PCNA PCNA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFWD3Ring finger and WD repeat domain 3. (765 aa)
TonslTonsoku-like protein. (64 aa)
CenpxCentromere protein X. (79 aa)
MRE11MRE11 homolog, double strand break repair nuclease. (708 aa)
WRNWerner syndrome ATP-dependent helicase. (1439 aa)
MCM9DNA replication licensing factor MCM9; Belongs to the MCM family. (1106 aa)
POLD1DNA polymerase delta 1, catalytic subunit. (933 aa)
FANCMFanconi anemia group M protein. (1984 aa)
NUCKS1Nuclear casein kinase and cyclin dependent kinase substrate 1. (227 aa)
EXD2Exonuclease 3'-5' domain-containing protein 2. (617 aa)
BOD1L1Biorientation of chromosomes in cell division protein 1-like. (2615 aa)
FBH1F-box only protein 18. (1042 aa)
H920_12726Uncharacterized protein. (234 aa)
DONSONDownstream neighbor of SON. (348 aa)
SMARCAL1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1. (907 aa)
BRCA2Breast cancer type 2 susceptibility protein. (3134 aa)
DDX11DEAD/H-box helicase 11. (772 aa)
CenpsCentromere protein S. (58 aa)
ALYREFAly/REF export factor. (227 aa)
Rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1419 aa)
EME1Crossover junction endonuclease EME1. (554 aa)
TRAIPTRAF-interacting protein. (469 aa)
ETAA1Ewing's tumor-associated antigen 1. (873 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (618 aa)
CDK9Cyclin dependent kinase 9. (378 aa)
LOC104851526Histone-lysine N-methyltransferase SETMAR. (299 aa)
THOC1THO complex subunit 1. (649 aa)
FAM111AProtein FAM111A. (616 aa)
ATRSerine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2644 aa)
H920_13460TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (74 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (869 aa)
EME2Putative crossover junction endonuclease EME2. (371 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
MUS81Crossover junction endonuclease MUS81. (539 aa)
MMS22LProtein MMS22-like. (1240 aa)
TIMELESSProtein timeless like protein. (1207 aa)
PRIMPOLCoiled-coil domain-containing protein 111. (545 aa)
ATRXTranscriptional regulator ATRX. (2492 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
BLMBloom syndrome protein. (1348 aa)
ZRANB3Zinc finger Ran-binding domain-containing protein 3. (1078 aa)
DNA2DNA2-like helicase. (1059 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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