STRINGSTRING
Ddx5 Ddx5 EPAS1 EPAS1 SHH SHH WNT3A WNT3A WNT10B WNT10B PITX1 PITX1 MAML1 MAML1 MYOCD MYOCD ENSFDAP00000009586 ENSFDAP00000009586 SDC1 SDC1 FGF6 FGF6 GPX1 GPX1 REST REST TBX2 TBX2 MEGF10 MEGF10 HINFP HINFP PLEKHM3 PLEKHM3 MBNL1 MBNL1 LGALS1 LGALS1 SOX15 SOX15 RB1 RB1 IGF1 IGF1 MAPK12 MAPK12 DICER1 DICER1 SRF SRF NOL3 NOL3 ITGB1 ITGB1 PLG PLG TBXT TBXT ISL1 ISL1 GREM1 GREM1 NRG1 NRG1 TCF7L2 TCF7L2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ddx5Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (600 aa)
EPAS1Endothelial PAS domain-containing protein 1. (869 aa)
SHHSonic hedgehog protein. (244 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
PITX1Homeobox protein. (290 aa)
MAML1Mastermind-like protein 1. (849 aa)
MYOCDMyocardin. (974 aa)
ENSFDAP00000009586annotation not available (571 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (233 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa)
GPX1Glutathione peroxidase 1. (145 aa)
RESTRE1-silencing transcription factor. (990 aa)
TBX2T-box transcription factor TBX2. (633 aa)
MEGF10Multiple epidermal growth factor-like domains protein 10. (1149 aa)
HINFPHistone H4 transcription factor. (448 aa)
PLEKHM3Pleckstrin homology domain-containing family M member 3. (759 aa)
MBNL1Muscleblind-like protein 1. (387 aa)
LGALS1Galectin. (125 aa)
SOX15Protein SOX-15. (229 aa)
RB1Retinoblastoma-associated protein. (882 aa)
IGF1Insulin-like growth factor I. (158 aa)
MAPK12Mitogen-activated protein kinase 12. (316 aa)
DICER1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1915 aa)
SRFSerum response factor. (337 aa)
NOL3Nucleolar protein 3. (205 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (803 aa)
PLGPlasminogen. (837 aa)
TBXTBrachyury protein. (436 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
GREM1Gremlin-1. (184 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform. (699 aa)
TCF7L2Transcription factor 7 like 2. (413 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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