STRINGSTRING
SMAD1 SMAD1 MYOCD MYOCD ZBTB7A ZBTB7A PRDM16 PRDM16 PPM1A PPM1A USP15 USP15 BMP2 BMP2 ZMIZ1 ZMIZ1 TGFBR2 TGFBR2 Yy1 Yy1 BMPR1B BMPR1B Smad9 Smad9 SNW1 SNW1 ENSFDAP00000004786 ENSFDAP00000004786 STUB1 STUB1 CREBBP CREBBP SMAD3 SMAD3 ACVRL1 ACVRL1 SKI SKI BMPR1A BMPR1A SMURF2 SMURF2 SMAD5 SMAD5 ENSFDAP00000008979 ENSFDAP00000008979 Fkbp1a Fkbp1a SKOR2 SKOR2 JUN JUN ENSFDAP00000009586 ENSFDAP00000009586 PARP1 PARP1 SMAD7 SMAD7 ZC3H3 ZC3H3 ANKRD1 ANKRD1 MAGI2 MAGI2 FERMT2 FERMT2 DROSHA DROSHA TGFBRAP1 TGFBRAP1 SKOR1 SKOR1 PML PML COL1A2 COL1A2 MEF2A MEF2A Ddx5 Ddx5 AXIN2 AXIN2 H920_09656 H920_09656 PMEPA1 PMEPA1 TGFBR1 TGFBR1 INTS8 INTS8 RANBP3L RANBP3L FOXA2 FOXA2 RGCC RGCC COL5A2 COL5A2 Cited1 Cited1 TGFBR3 TGFBR3 SMAD2 SMAD2 ACVR1C ACVR1C ZEB2 ZEB2 PPARG PPARG Gata4 Gata4 ACVR1B ACVR1B TRIM33 TRIM33 DAB2 DAB2 SMURF1 SMURF1 FOXH1 FOXH1 MEN1 MEN1 Ctnnb1 Ctnnb1 FLNA FLNA RNF111 RNF111 COL3A1 COL3A1 RANBP3 RANBP3 Tgif1 Tgif1 PAX6 PAX6 SMAD4 SMAD4 USP9X USP9X FOS FOS SAV1 SAV1 AXIN1 AXIN1 ACVR1 ACVR1 SKIL SKIL CREB3L1 CREB3L1 EID2 EID2 CITED2 CITED2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD1Mothers against decapentaplegic homolog. (465 aa)
MYOCDMyocardin. (974 aa)
ZBTB7AZinc finger and BTB domain-containing protein 7A. (511 aa)
PRDM16PR domain zinc finger protein 16. (1257 aa)
PPM1AProtein phosphatase 1A; Belongs to the PP2C family. (382 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1. (1076 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (560 aa)
Yy1YY1 transcription factor. (189 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
Smad9Mothers against decapentaplegic homolog. (430 aa)
SNW1SNW domain containing 1. (537 aa)
ENSFDAP00000004786annotation not available (71 aa)
STUB1STIP1 homology and U box-containing protein 1. (250 aa)
CREBBPCREB-binding protein. (2426 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
SKISki oncogene. (704 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SMURF2E3 ubiquitin-protein ligase. (742 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ENSFDAP00000008979annotation not available (180 aa)
Fkbp1aPeptidylprolyl isomerase. (108 aa)
SKOR2SKI family transcriptional corepressor 2. (578 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (254 aa)
ENSFDAP00000009586annotation not available (571 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (973 aa)
SMAD7Mothers against decapentaplegic homolog. (229 aa)
ZC3H3Zinc finger CCCH domain-containing protein 3. (950 aa)
ANKRD1Ankyrin repeat domain-containing protein 1. (318 aa)
MAGI2Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (1133 aa)
FERMT2Fermitin family like protein 2. (716 aa)
DROSHARibonuclease 3. (1376 aa)
TGFBRAP1Transforming growth factor-beta receptor-associated protein 1. (856 aa)
SKOR1SKI family transcriptional corepressor 1. (642 aa)
PMLProtein PML. (634 aa)
COL1A2Collagen alpha-2(I) chain. (1366 aa)
MEF2AMyocyte-specific enhancer factor 2A. (505 aa)
Ddx5Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (600 aa)
AXIN2Axin-2. (860 aa)
H920_09656Catenin beta-1. (83 aa)
PMEPA1Transmembrane prostate androgen-induced protein. (234 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (470 aa)
INTS8Integrator complex subunit 8. (990 aa)
RANBP3LRAN binding protein 3 like. (486 aa)
FOXA2Hepatocyte nuclear factor 3-beta. (429 aa)
RGCCResponse gene to complement 32 protein. (120 aa)
COL5A2Collagen alpha-2(V) chain. (1499 aa)
Cited1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (61 aa)
TGFBR3Transforming growth factor beta receptor type 3. (850 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (468 aa)
ZEB2Zinc finger E-box-binding homeobox 2. (1254 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
Gata4Transcription factor GATA-4. (215 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (494 aa)
TRIM33E3 ubiquitin-protein ligase TRIM33. (951 aa)
DAB2Disabled like protein 2. (769 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (744 aa)
FOXH1Forkhead box protein H1. (367 aa)
MEN1Menin. (616 aa)
Ctnnb1Catenin beta-1. (781 aa)
FLNAFilamin-A. (2647 aa)
RNF111E3 ubiquitin-protein ligase Arkadia; Belongs to the cyclin family. (987 aa)
COL3A1Collagen alpha-1(III) chain. (1463 aa)
RANBP3RAN binding protein 3. (407 aa)
Tgif1Homeobox protein TGIF1. (79 aa)
PAX6Paired box protein Pax-6. (436 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
USP9XPutative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2554 aa)
FOSProto-oncogene c-Fos. (380 aa)
SAV1Protein salvador like protein 1. (384 aa)
AXIN1Axin-1. (865 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
SKILSki-like protein. (679 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (447 aa)
EID2EP300-interacting inhibitor of differentiation 2. (198 aa)
CITED2Cbp/p300-interacting transactivator 2. (220 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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