26 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ITGA8	Integrin alpha-8; Belongs to the integrin alpha chain family. (992 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (591 aa)
	Pou5f1	POU domain protein. (280 aa)
	ENSFDAP00000004786	annotation not available (71 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	NODAL	Nodal growth differentiation factor. (322 aa)
	KDM6A	Lysine-specific demethylase 6A. (1370 aa)
	TBX6	T-box transcription factor TBX6. (436 aa)
	ITGA3	Integrin alpha-3; Belongs to the integrin alpha chain family. (1000 aa)
	FGFR2	Fibroblast growth factor receptor. (840 aa)
	FOXF1	Forkhead box F1. (345 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
	KDM6B	Lysine demethylase 6B. (1653 aa)
	Nanog	Homeobox protein NANOG. (224 aa)
	PAX2	Paired box protein Pax-2. (359 aa)
	INHBA	Inhibin beta A chain. (424 aa)
	TAF10	Transcription initiation factor TFIID subunit 10. (175 aa)
	Itgb3	Integrin beta; Belongs to the integrin beta chain family. (761 aa)
	LOC104866854	Lysine-specific demethylase 6A-like. (588 aa)
	SIX2	Homeobox protein SIX2. (295 aa)
	H920_12466	ETS domain-containing protein. (155 aa)
	SFRP2	Secreted frizzled-related protein 2. (286 aa)
	BMP4	Bone morphogenetic protein 4. (410 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (803 aa)
	ITGA2	Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
	ITGB4	Integrin beta. (1761 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	FGFR2	ENSFDAP00000019587	ENSFDAP00000010657	Bone morphogenetic protein 4.	Fibroblast growth factor receptor.	0.400
BMP4	FOXF1	ENSFDAP00000019587	ENSFDAP00000011446	Bone morphogenetic protein 4.	Forkhead box F1.	0.667
BMP4	ITGA3	ENSFDAP00000019587	ENSFDAP00000010359	Bone morphogenetic protein 4.	Integrin alpha-3; Belongs to the integrin alpha chain family.	0.402
BMP4	ITGB1	ENSFDAP00000019587	ENSFDAP00000022103	Bone morphogenetic protein 4.	Integrin beta; Belongs to the integrin beta chain family.	0.507
BMP4	ITGB4	ENSFDAP00000019587	ENSFDAP00000022824	Bone morphogenetic protein 4.	Integrin beta.	0.472
BMP4	Itgb3	ENSFDAP00000019587	ENSFDAP00000016006	Bone morphogenetic protein 4.	Integrin beta; Belongs to the integrin beta chain family.	0.472
BMP4	NODAL	ENSFDAP00000019587	ENSFDAP00000005864	Bone morphogenetic protein 4.	Nodal growth differentiation factor.	0.589
BMP4	Nanog	ENSFDAP00000019587	ENSFDAP00000014098	Bone morphogenetic protein 4.	Homeobox protein NANOG.	0.419
BMP4	Pou5f1	ENSFDAP00000019587	ENSFDAP00000004134	Bone morphogenetic protein 4.	POU domain protein.	0.443
BMP4	SMAD1	ENSFDAP00000019587	ENSFDAP00000005398	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.816
BMP4	WNT3A	ENSFDAP00000019587	ENSFDAP00000011843	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.442
EYA1	PAX2	ENSFDAP00000001314	ENSFDAP00000014724	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Paired box protein Pax-2.	0.539
EYA1	SIX2	ENSFDAP00000001314	ENSFDAP00000016222	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein SIX2.	0.827
FGFR2	BMP4	ENSFDAP00000010657	ENSFDAP00000019587	Fibroblast growth factor receptor.	Bone morphogenetic protein 4.	0.400
FGFR2	TBX6	ENSFDAP00000010657	ENSFDAP00000007463	Fibroblast growth factor receptor.	T-box transcription factor TBX6.	0.468
FOXF1	BMP4	ENSFDAP00000011446	ENSFDAP00000019587	Forkhead box F1.	Bone morphogenetic protein 4.	0.667
FOXF1	SMAD1	ENSFDAP00000011446	ENSFDAP00000005398	Forkhead box F1.	Mothers against decapentaplegic homolog.	0.465
H920_12466	PAX2	ENSFDAP00000018749	ENSFDAP00000014724	ETS domain-containing protein.	Paired box protein Pax-2.	0.408
INHBA	NODAL	ENSFDAP00000022924	ENSFDAP00000005864	Inhibin beta A chain.	Nodal growth differentiation factor.	0.901
INHBA	SMAD1	ENSFDAP00000022924	ENSFDAP00000005398	Inhibin beta A chain.	Mothers against decapentaplegic homolog.	0.542