(11 nodes) Paraxial mesoderm morphogenesis network (Fukomys damarensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCKAP1	Nck-associated protein 1. (1098 aa)
	SMAD3	Mothers against decapentaplegic homolog. (429 aa)
	EXOC4	Exocyst complex component 4. (975 aa)
	HNF1A	Hepatocyte nuclear factor 1-alpha. (631 aa)
	LEF1	Lymphoid enhancer-binding factor 1. (329 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
	HTT	Huntingtin. (3051 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	BMPR1A	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMPR1A	NCKAP1	ENSFDAP00000006958	ENSFDAP00000004966	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Nck-associated protein 1.	0.419
BMPR1A	SMAD2	ENSFDAP00000006958	ENSFDAP00000015181	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.914
BMPR1A	SMAD3	ENSFDAP00000006958	ENSFDAP00000005300	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.947
LEF1	SMAD2	ENSFDAP00000012153	ENSFDAP00000015181	Lymphoid enhancer-binding factor 1.	Mothers against decapentaplegic homolog.	0.825
LEF1	SMAD3	ENSFDAP00000012153	ENSFDAP00000005300	Lymphoid enhancer-binding factor 1.	Mothers against decapentaplegic homolog.	0.822
LEF1	WNT11	ENSFDAP00000012153	ENSFDAP00000011136	Lymphoid enhancer-binding factor 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.544
LEF1	WNT3A	ENSFDAP00000012153	ENSFDAP00000011843	Lymphoid enhancer-binding factor 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.563
LEF1	WNT5A	ENSFDAP00000012153	ENSFDAP00000017304	Lymphoid enhancer-binding factor 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.571
NCKAP1	BMPR1A	ENSFDAP00000004966	ENSFDAP00000006958	Nck-associated protein 1.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.419
SMAD2	BMPR1A	ENSFDAP00000015181	ENSFDAP00000006958	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.914
SMAD2	LEF1	ENSFDAP00000015181	ENSFDAP00000012153	Mothers against decapentaplegic homolog.	Lymphoid enhancer-binding factor 1.	0.825
SMAD2	SMAD3	ENSFDAP00000015181	ENSFDAP00000005300	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.994
SMAD3	BMPR1A	ENSFDAP00000005300	ENSFDAP00000006958	Mothers against decapentaplegic homolog.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.947
SMAD3	LEF1	ENSFDAP00000005300	ENSFDAP00000012153	Mothers against decapentaplegic homolog.	Lymphoid enhancer-binding factor 1.	0.822
SMAD3	SMAD2	ENSFDAP00000005300	ENSFDAP00000015181	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.994
WNT11	LEF1	ENSFDAP00000011136	ENSFDAP00000012153	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Lymphoid enhancer-binding factor 1.	0.544
WNT11	WNT3A	ENSFDAP00000011136	ENSFDAP00000011843	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.645
WNT11	WNT5A	ENSFDAP00000011136	ENSFDAP00000017304	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.624
WNT3A	LEF1	ENSFDAP00000011843	ENSFDAP00000012153	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Lymphoid enhancer-binding factor 1.	0.563
WNT3A	WNT11	ENSFDAP00000011843	ENSFDAP00000011136	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.645