STRINGSTRING
RARG RARG TGFBR1 TGFBR1 NEUROG1 NEUROG1 Col9a1 Col9a1 ANXA6 ANXA6 EXT2 EXT2 ENSFDAP00000000217 ENSFDAP00000000217 HOXA5 HOXA5 H920_08154 H920_08154 IFITM5 IFITM5 HOXA1 HOXA1 HHIP HHIP WWOX WWOX LRP5 LRP5 COL2A1 COL2A1 RIPPLY2 RIPPLY2 Cbs Cbs ACVR2B ACVR2B EYA1 EYA1 PCGF2 PCGF2 CYP26B1 CYP26B1 RYK RYK SH3PXD2B SH3PXD2B POC1A POC1A BARX2 BARX2 H920_19388 H920_19388 MMP13 MMP13 PRRX1 PRRX1 ACTN3 ACTN3 MDFI MDFI LHX1 LHX1 WNT9A WNT9A RARA RARA Zfand5 Zfand5 TGFBR2 TGFBR2 HYAL1 HYAL1 TGFB2 TGFB2 COL11A2 COL11A2 EXT1 EXT1 LRP6 LRP6 NDST1 NDST1 ALX3 ALX3 PRKRA PRKRA SOX9 SOX9 BMPR1B BMPR1B BMP7 BMP7 CHSY1 CHSY1 TRPV4 TRPV4 ROR2 ROR2 Fgf4 Fgf4 SIX4 SIX4 HSPG2 HSPG2 WDR48 WDR48 MAPK14 MAPK14 SMAD3 SMAD3 TMEM107 TMEM107 ZMPSTE24 ZMPSTE24 ENPP1 ENPP1 NODAL NODAL ENSFDAP00000005893 ENSFDAP00000005893 RAB23 RAB23 PHOSPHO2 PHOSPHO2 COL11A1 COL11A1 OTOR OTOR THRA THRA RECQL4 RECQL4 THBS3 THBS3 ENSFDAP00000006543 ENSFDAP00000006543 SKI SKI ACP5 ACP5 SFRP1 SFRP1 H920_03637 H920_03637 DLX2 DLX2 MSX2 MSX2 WNT9B WNT9B CER1 CER1 ANKRD11 ANKRD11 INPPL1 INPPL1 IFT80 IFT80 OSR1 OSR1 STC1 STC1 HAS2 HAS2 INSIG2 INSIG2 COMP COMP MATN1 MATN1 PEX7 PEX7 IMPAD1 IMPAD1 SOX6 SOX6 WDR60 WDR60 Hoxc8 Hoxc8 RAB33B RAB33B FGF6 FGF6 BMP6 BMP6 DSCAML1 DSCAML1 MEGF8 MEGF8 FUZ FUZ HYAL2 HYAL2 WDR19 WDR19 MTHFD1L MTHFD1L NIPBL NIPBL CSRNP1 CSRNP1 FGFR2 FGFR2 HOXC11 HOXC11 PAX5 PAX5 SIK3 SIK3 IFT140 IFT140 COL27A1 COL27A1 PKD1 PKD1 LOC104865308 LOC104865308 GLI3 GLI3 LTF LTF FGF18 FGF18 FOXN3 FOXN3 WNT10B WNT10B Atg9a Atg9a COL10A1 COL10A1 RDH10 RDH10 ALPL ALPL COL13A1 COL13A1 SETD2 SETD2 MMP14 MMP14 FGR FGR FLVCR1 FLVCR1 DHRS3 DHRS3 CHST11 CHST11 AXIN2 AXIN2 H920_09656 H920_09656 EIF4A3 EIF4A3 LTBP3 LTBP3 NPPC NPPC Hoxa2 Hoxa2 SGPL1 SGPL1 TGFB3 TGFB3 THBS1 THBS1 ARID5B ARID5B HOXC9 HOXC9 Bmi1 Bmi1 ZEB1 ZEB1 HOXB1 HOXB1 RFLNB RFLNB SCUBE2 SCUBE2 SMAD2 SMAD2 TBX4 TBX4 GSC GSC COL1A1 COL1A1 SLC39A1 SLC39A1 SIX2 SIX2 MMP2 MMP2 SIX1 SIX1 OSR2 OSR2 PSEN1 PSEN1 H920_03964 H920_03964 SHOX2 SHOX2 HOXB9 HOXB9 ALX4 ALX4 ENSFDAP00000017336 ENSFDAP00000017336 RARB RARB HOXD3 HOXD3 GLG1 GLG1 TBXT TBXT PAPPA2 PAPPA2 SCX SCX TULP3 TULP3 FGFR3 FGFR3 GRHL2 GRHL2 MEN1 MEN1 Hoxd8 Hoxd8 NLE1 NLE1 ANKRD12 ANKRD12 FGF8 FGF8 P2RX7 P2RX7 ATF2 ATF2 Ctnnb1 Ctnnb1 SFRP4 SFRP4 BMP4 BMP4 TRIP11 TRIP11 MEF2C MEF2C HOXA7 HOXA7 TIPARP TIPARP PPARGC1B PPARGC1B HOXD10 HOXD10 ASXL2 ASXL2 COL3A1 COL3A1 SMPD3 SMPD3 H920_20317 H920_20317 FBN2 FBN2 MMP16 MMP16 TBX15 TBX15 CSGALNACT1 CSGALNACT1 MED12 MED12 CARM1 CARM1 HOXA11 HOXA11 H920_03634 H920_03634 BMPR2 BMPR2 MYF5 MYF5 HOXB5 HOXB5 SERPINH1 SERPINH1 PAX1 PAX1 TFAP2A TFAP2A IHH IHH RUNX2 RUNX2 MEF2D MEF2D IDUA IDUA SLC39A3 SLC39A3 PDGFRA PDGFRA INSIG1 INSIG1 HOXD4 HOXD4 CITED2 CITED2 SULF1 SULF1 PDGFRB PDGFRB DLX5 DLX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RARGRetinoic acid receptor gamma. (462 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (470 aa)
NEUROG1Neurogenin-1. (241 aa)
Col9a1Collagen alpha-1(IX) chain. (910 aa)
ANXA6Annexin. (646 aa)
EXT2Exostosin-2; Belongs to the glycosyltransferase 47 family. (717 aa)
ENSFDAP00000000217annotation not available (93 aa)
HOXA5Homeobox protein Hox-A5. (182 aa)
H920_08154FRAS1-related extracellular matrix protein 1. (1326 aa)
IFITM5Interferon-induced transmembrane protein 5. (134 aa)
HOXA1Homeobox protein Hox-A1. (333 aa)
HHIPHedgehog-interacting protein. (682 aa)
WWOXWW domain-containing oxidoreductase. (378 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1645 aa)
COL2A1Collagen alpha-1(II) chain. (1487 aa)
RIPPLY2Ripply transcriptional repressor 2. (107 aa)
CbsCystathionine beta-synthase. (515 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (591 aa)
PCGF2Polycomb group RING finger protein 2. (344 aa)
CYP26B1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (480 aa)
RYKTyrosine-protein kinase RYK. (532 aa)
SH3PXD2BSH3 and PX domain-containing protein 2B. (882 aa)
POC1APOC1 centriolar protein like protein A. (407 aa)
BARX2Homeobox protein BarH-like 2. (243 aa)
H920_19388TRAF-interacting protein with FHA domain-containing protein B. (250 aa)
MMP13Collagenase 3. (471 aa)
PRRX1Paired mesoderm homeobox protein 1. (235 aa)
ACTN3Alpha-actinin-3. (900 aa)
MDFIMyoD family inhibitor. (176 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
RARARetinoic acid receptor alpha. (421 aa)
Zfand5AN1-type zinc finger protein 5. (213 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (560 aa)
HYAL1Hyaluronidase 1. (462 aa)
TGFB2Transforming growth factor beta 2. (398 aa)
COL11A2Collagen alpha-2(XI) chain. (1668 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
LRP6Low-density lipoprotein receptor-related protein 6. (1463 aa)
NDST1Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1. (882 aa)
ALX3Homeobox protein aristaless-like 3. (302 aa)
PRKRAInterferon-inducible double stranded RNA-dependent protein kinase activator A. (307 aa)
SOX9Transcription factor Sox-9-B. (430 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
BMP7Bone morphogenetic protein 7. (432 aa)
CHSY1Hexosyltransferase. (695 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
ROR2Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
Fgf4Fibroblast growth factor 4. (52 aa)
SIX4Homeobox protein SIX4. (592 aa)
HSPG2Basement membrane-specific heparan sulfate proteoglycan core protein. (4246 aa)
WDR48WD repeat-containing protein 48. (677 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
TMEM107Transmembrane protein 107. (140 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (873 aa)
NODALNodal growth differentiation factor. (322 aa)
ENSFDAP00000005893annotation not available (140 aa)
RAB23Ras-related protein Rab-23. (237 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
COL11A1Collagen alpha-1(XI) chain. (1805 aa)
OTOROtoraplin. (128 aa)
THRAThyroid hormone receptor alpha. (515 aa)
RECQL4ATP-dependent DNA helicase Q4. (1197 aa)
THBS3Thrombospondin-3. (956 aa)
ENSFDAP00000006543annotation not available (498 aa)
SKISki oncogene. (704 aa)
ACP5Acid phosphatase 5, tartrate resistant. (327 aa)
SFRP1Secreted frizzled-related protein 1. (285 aa)
H920_03637Homeobox protein Hox-B7. (115 aa)
DLX2Homeobox protein DLX-2. (301 aa)
MSX2Homeobox protein MSX-2. (268 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
CER1Cerberus. (267 aa)
ANKRD11Ankyrin repeat domain-containing protein 11. (2650 aa)
INPPL1Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2. (1225 aa)
IFT80Intraflagellar transport protein 80 like protein. (777 aa)
OSR1Protein odd-skipped-related 1. (266 aa)
STC1Stanniocalcin-1. (247 aa)
HAS2Hyaluronan synthase 2. (552 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
COMPCartilage oligomeric matrix protein. (712 aa)
MATN1Cartilage matrix protein. (496 aa)
PEX7Peroxisomal targeting signal 2 receptor. (301 aa)
IMPAD1Inositol monophosphatase 3. (298 aa)
SOX6Transcription factor SOX-6. (828 aa)
WDR60WD repeat-containing protein 60. (1066 aa)
Hoxc8Homeobox protein Hox-C8. (242 aa)
RAB33BRas-related protein Rab-33B. (229 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa)
BMP6Bone morphogenetic protein 6. (319 aa)
DSCAML1Down syndrome cell adhesion molecule-like protein 1. (2037 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2809 aa)
FUZProtein fuzzy like protein. (415 aa)
HYAL2Hyaluronidase. (471 aa)
WDR19WD repeat-containing protein 19. (1342 aa)
MTHFD1LMonofunctional C1-tetrahydrofolate synthase, mitochondrial. (902 aa)
NIPBLNipped-B protein. (2804 aa)
CSRNP1Cysteine/serine-rich nuclear protein 1. (589 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
HOXC11Homeobox C11. (251 aa)
PAX5Paired box protein Pax-5. (391 aa)
SIK3Serine/threonine-protein kinase SIK3. (1278 aa)
IFT140Intraflagellar transport protein 140 like protein. (1456 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1609 aa)
PKD1Polycystin-1. (4269 aa)
LOC104865308Neuroendocrine secretory protein 55. (229 aa)
GLI3Transcriptional activator GLI3. (1570 aa)
LTFLactotransferrin; Belongs to the transferrin family. (715 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FOXN3Forkhead box protein N3. (485 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
Atg9aAutophagy-related protein 9A. (839 aa)
COL10A1Collagen alpha-1(X) chain. (680 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (263 aa)
ALPLAlkaline phosphatase. (531 aa)
COL13A1Collagen alpha-1(XIII) chain. (631 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2538 aa)
MMP14Matrix metallopeptidase 14. (546 aa)
FGRTyrosine-protein kinase. (526 aa)
FLVCR1Feline leukemia virus subgroup C receptor-related protein 1. (456 aa)
DHRS3Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
CHST11Carbohydrate sulfotransferase. (312 aa)
AXIN2Axin-2. (860 aa)
H920_09656Catenin beta-1. (83 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (425 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3. (1131 aa)
NPPCC-type natriuretic peptide. (126 aa)
Hoxa2Homeobox protein Hox-A2. (370 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
THBS1Thrombospondin-1. (1181 aa)
ARID5BAT-rich interactive domain-containing protein 5B. (1188 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
Bmi1Polycomb complex protein BMI-1. (326 aa)
ZEB1Zinc finger E-box-binding homeobox 1. (1110 aa)
HOXB1Homeobox B1. (243 aa)
RFLNBProtein FAM101B. (146 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2. (954 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TBX4T-box transcription factor TBX4. (550 aa)
GSCHomeobox protein goosecoid. (145 aa)
COL1A1Collagen alpha-1(I) chain. (1453 aa)
SLC39A1Solute carrier family 39 member 1. (324 aa)
SIX2Homeobox protein SIX2. (295 aa)
MMP2Matrix metallopeptidase 2. (644 aa)
SIX1Homeobox protein SIX1. (284 aa)
OSR2Protein odd-skipped-related 2. (276 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
H920_03964Aggrecan core protein. (711 aa)
SHOX2Short stature homeobox 2. (270 aa)
HOXB9Homeobox protein Hox-B9. (133 aa)
ALX4Homeobox protein aristaless-like 4. (371 aa)
ENSFDAP00000017336annotation not available (225 aa)
RARBRetinoic acid receptor beta. (448 aa)
HOXD3Homeobox protein Hox-D3. (432 aa)
GLG1Golgi apparatus protein 1. (1184 aa)
TBXTBrachyury protein. (436 aa)
PAPPA2Pappalysin-2. (1789 aa)
SCXScleraxis bHLH transcription factor. (129 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (449 aa)
FGFR3Fibroblast growth factor receptor 3. (748 aa)
GRHL2Grainyhead like transcription factor 2. (517 aa)
MEN1Menin. (616 aa)
Hoxd8Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (106 aa)
NLE1Notchless protein like protein 1. (485 aa)
ANKRD12Ankyrin repeat domain-containing protein 12. (2047 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
P2RX7p2X purinoceptor 7. (583 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (505 aa)
Ctnnb1Catenin beta-1. (781 aa)
SFRP4Secreted frizzled-related protein 4. (316 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
TRIP11Thyroid receptor-interacting protein 11. (1960 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
HOXA7Homeobox A7. (230 aa)
TIPARPTCDD-inducible poly [ADP-ribose] polymerase. (657 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta. (1004 aa)
HOXD10Homeobox protein Hox-D10. (340 aa)
ASXL2Putative Polycomb group protein ASXL2. (1406 aa)
COL3A1Collagen alpha-1(III) chain. (1463 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (569 aa)
H920_20317AN1-type zinc finger protein 5. (188 aa)
FBN2Fibrillin-2. (2820 aa)
MMP16Matrix metalloproteinase-16. (607 aa)
TBX15T-box transcription factor TBX15. (602 aa)
CSGALNACT1Hexosyltransferase. (528 aa)
MED12Mediator of RNA polymerase II transcription subunit 12. (2178 aa)
CARM1Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (558 aa)
HOXA11Homeobox protein Hox-D11. (314 aa)
H920_03634Homeobox protein Hox-B4. (146 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1025 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
HOXB5Homeobox protein Hox-B5. (247 aa)
SERPINH1Serpin H1; Belongs to the serpin family. (418 aa)
PAX1Paired box protein Pax-1. (362 aa)
TFAP2ATranscription factor AP-2 alpha. (382 aa)
IHHIndian hedgehog signaling molecule. (370 aa)
RUNX2Runt-related transcription factor 2. (508 aa)
MEF2DMyocyte-specific enhancer factor 2D. (483 aa)
IDUAAlpha-L-iduronidase. (457 aa)
SLC39A3Zinc transporter ZIP3. (316 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
INSIG1Insulin induced gene 1. (255 aa)
HOXD4Homeobox protein Hox-D4. (204 aa)
CITED2Cbp/p300-interacting transactivator 2. (220 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1097 aa)
DLX5Homeobox protein DLX-5. (289 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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