STRINGSTRING
ARG1 ARG1 H920_05445 H920_05445 IGF1 IGF1 BAX BAX SNX10 SNX10 CCDC154 CCDC154 LRP5 LRP5 Cbs Cbs ACVR2B ACVR2B WNT16 WNT16 GJA5 GJA5 TGFB2 TGFB2 LIPA LIPA EXT1 EXT1 LRP6 LRP6 TCIRG1 TCIRG1 CTHRC1 CTHRC1 RAC1 RAC1 ACVRL1 ACVRL1 ENPP1 ENPP1 LIF LIF NOTCH2 NOTCH2 IL23A IL23A ACP5 ACP5 NOS3 NOS3 RBPJ RBPJ AXL AXL ENSFDAP00000007466 ENSFDAP00000007466 THBS4 THBS4 EFNA2 EFNA2 SLC34A1 SLC34A1 IAPP IAPP FGF10 FGF10 ITGA4 ITGA4 MITF MITF GDF5 GDF5 RASSF2 RASSF2 NOX4 NOX4 DBH DBH HTR1B HTR1B GPR55 GPR55 ELF3 ELF3 RSPO3 RSPO3 IL7 IL7 H920_06451 H920_06451 EPAS1 EPAS1 GSK3B GSK3B MMP14 MMP14 RAB3D RAB3D H920_09656 H920_09656 PTH1R PTH1R TPH1 TPH1 TPP1 TPP1 ATP7A ATP7A LTBP3 LTBP3 Atg5 Atg5 CHD7 CHD7 TGFB3 TGFB3 TIE1 TIE1 CTSK CTSK CTSS CTSS TGFBR3 TGFBR3 TRAF6 TRAF6 NCDN NCDN BSX BSX PTK2B PTK2B IGFBP5 IGFBP5 CLEC10A CLEC10A MMP2 MMP2 PTN PTN DLL4 DLL4 UMOD UMOD JAG1 JAG1 ENSFDAP00000017826 ENSFDAP00000017826 TNFSF11 TNFSF11 FGF8 FGF8 BAK1 BAK1 TIMP1 TIMP1 SEMA3C SEMA3C Ctnnb1 Ctnnb1 Ahr Ahr VDR VDR CRB1 CRB1 FLNA FLNA MEF2C MEF2C NFATC3 NFATC3 CAV1 CAV1 EDNRA EDNRA CSPG4 CSPG4 RAB7A RAB7A H920_14216 H920_14216 LRRK1 LRRK1 EPHA2 EPHA2 PLG PLG TGFB1 TGFB1 CAPN1 CAPN1 BMPR2 BMPR2 SPP2 SPP2 CELA1 CELA1 MMP9 MMP9 F2R F2R NOL3 NOL3 HNF1A HNF1A HIF1A HIF1A IHH IHH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARG1Arginase. (323 aa)
H920_05445C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (499 aa)
IGF1Insulin-like growth factor I. (158 aa)
BAXApoptosis regulator BAX. (180 aa)
SNX10Sorting nexin-10. (201 aa)
CCDC154Coiled-coil domain-containing protein 154. (632 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1645 aa)
CbsCystathionine beta-synthase. (515 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (357 aa)
TGFB2Transforming growth factor beta 2. (398 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
LRP6Low-density lipoprotein receptor-related protein 6. (1463 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (832 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (252 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (199 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (873 aa)
LIFLeukemia inhibitory factor. (202 aa)
NOTCH2Uncharacterized protein. (2418 aa)
IL23AInterleukin-23 subunit alpha. (189 aa)
ACP5Acid phosphatase 5, tartrate resistant. (327 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1206 aa)
RBPJRecombining binding protein suppressor of hairless. (526 aa)
AXLTyrosine-protein kinase receptor UFO. (889 aa)
ENSFDAP00000007466annotation not available (44 aa)
THBS4Thrombospondin-4. (901 aa)
EFNA2Ephrin-A2; Belongs to the ephrin family. (200 aa)
SLC34A1Sodium-dependent phosphate transport protein 2A. (638 aa)
IAPPIslet amyloid polypeptide. (93 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (967 aa)
MITFMicrophthalmia-associated transcription factor. (510 aa)
GDF5Growth differentiation factor 5. (495 aa)
RASSF2Ras association domain-containing protein 2. (326 aa)
NOX4NADPH oxidase 4. (559 aa)
DBHDopamine beta-hydroxylase. (622 aa)
HTR1B5-hydroxytryptamine receptor 1B. (384 aa)
GPR55G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (359 aa)
ELF3ETS-related transcription factor Elf-3. (273 aa)
RSPO3R-spondin-3. (244 aa)
IL7Interleukin-7. (152 aa)
H920_06451Chondroitin sulfate proteoglycan 4. (803 aa)
EPAS1Endothelial PAS domain-containing protein 1. (869 aa)
GSK3BGlycogen synthase kinase 3 beta. (442 aa)
MMP14Matrix metallopeptidase 14. (546 aa)
RAB3DRas-related protein Rab-3D. (219 aa)
H920_09656Catenin beta-1. (83 aa)
PTH1RParathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (578 aa)
TPH1Tryptophan 5-hydroxylase 1. (445 aa)
TPP1Tripeptidyl-peptidase 1. (563 aa)
ATP7ACopper-transporting ATPase 1. (1500 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3. (1131 aa)
Atg5Autophagy protein 5; Involved in autophagic vesicle formation. (198 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2990 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TIE1Tyrosine-protein kinase receptor Tie-1. (1139 aa)
CTSKCathepsin K. (328 aa)
CTSSGolgi phosphoprotein 3-like; Belongs to the peptidase C1 family. (331 aa)
TGFBR3Transforming growth factor beta receptor type 3. (850 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
NCDNNeurochondrin. (729 aa)
BSXBrain specific homeobox. (199 aa)
PTK2BProtein-tyrosine kinase 2-beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
IGFBP5Insulin-like growth factor-binding protein 5. (271 aa)
CLEC10AMacrophage asialoglycoprotein-binding protein 1. (303 aa)
MMP2Matrix metallopeptidase 2. (644 aa)
PTNPleiotrophin. (168 aa)
DLL4Delta like canonical Notch ligand 4. (851 aa)
UMODUromodulin. (500 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1191 aa)
ENSFDAP00000017826annotation not available (133 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (287 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
BAK1Bcl-2 like proteinous antagonist/killer. (212 aa)
TIMP1Metalloproteinase inhibitor 1. (207 aa)
SEMA3CSemaphorin-3C; Belongs to the semaphorin family. (750 aa)
Ctnnb1Catenin beta-1. (781 aa)
AhrAryl hydrocarbon receptor. (839 aa)
VDRVitamin D3 receptor. (419 aa)
CRB1Crumbs like protein 1. (1271 aa)
FLNAFilamin-A. (2647 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3. (1043 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
EDNRAEndothelin receptor type A. (427 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2321 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
H920_14216ETS-related transcription factor Elf-3. (494 aa)
LRRK1Leucine-rich repeat serine/threonine-protein kinase 1. (2015 aa)
EPHA2Ephrin type-A receptor 2. (947 aa)
PLGPlasminogen. (837 aa)
TGFB1Transforming growth factor beta-1. (333 aa)
CAPN1Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (714 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1025 aa)
SPP2Secreted phosphoprotein 24. (209 aa)
CELA1Bridging integrator 2. (266 aa)
MMP9Matrix metalloproteinase-9. (709 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (403 aa)
NOL3Nucleolar protein 3. (205 aa)
HNF1AHepatocyte nuclear factor 1-alpha. (631 aa)
HIF1AHypoxia-inducible factor 1-alpha. (815 aa)
IHHIndian hedgehog signaling molecule. (370 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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