STRINGSTRING
RASA3 RASA3 Camk2d Camk2d NF1 NF1 RALGPS1 RALGPS1 MAP2K1 MAP2K1 MADD MADD NOTCH2 NOTCH2 CDC42SE2 CDC42SE2 OGT OGT Eps8l3 Eps8l3 NGFR NGFR RASGRP4 RASGRP4 ENSFDAP00000005046 ENSFDAP00000005046 ARHGEF28 ARHGEF28 TRIM67 TRIM67 F11R F11R Arhgap26 Arhgap26 GABARAP GABARAP DENND3 DENND3 SYDE1 SYDE1 DLC1 DLC1 Rtn4 Rtn4 CBL CBL EPO EPO ARFGAP1 ARFGAP1 RALGAPA2 RALGAPA2 DENND4B DENND4B HEG1 HEG1 SPRY1 SPRY1 STMN1 STMN1 ARHGEF2 ARHGEF2 CADM4 CADM4 CYTH1 CYTH1 ARFGEF1 ARFGEF1 LRRC59 LRRC59 LRRD1 LRRD1 LOC104858674 LOC104858674 ABL1 ABL1 ARHGAP17 ARHGAP17 PIK3CB PIK3CB EPS8 EPS8 DGKI DGKI ARHGEF10 ARHGEF10 EPHB2 EPHB2 SSX2IP SSX2IP ADCYAP1R1 ADCYAP1R1 ARFGEF2 ARFGEF2 KCTD13 KCTD13 Eps8l1 Eps8l1 FAM49B FAM49B RASGRF1 RASGRF1 SGSM3 SGSM3 SYDE2 SYDE2 DNM2 DNM2 RAB3GAP1 RAB3GAP1 IGF1 IGF1 ARHGDIA ARHGDIA ARHGAP18 ARHGAP18 Rap1gap2 Rap1gap2 TGFB2 TGFB2 LOC104862775 LOC104862775 CD2AP CD2AP IQSEC3 IQSEC3 ARHGAP25 ARHGAP25 COL3A1 COL3A1 KIAA1755 KIAA1755 PSD2 PSD2 Arhgap19 Arhgap19 ADGRG1 ADGRG1 ITPKB ITPKB ARHGDIB ARHGDIB GARNL3 GARNL3 FLOT1 FLOT1 ABL2 ABL2 IQSEC1 IQSEC1 ROBO1 ROBO1 PLCE1 PLCE1 APOE APOE H920_09510 H920_09510 BCL6 BCL6 CDON CDON PSD3 PSD3 MAP4K4 MAP4K4 RIPOR2 RIPOR2 ITGB1 ITGB1 RTN4R RTN4R Sh3bp1 Sh3bp1 EPS8L2 EPS8L2 ARFGEF3 ARFGEF3 RASA1 RASA1 RELN RELN F2R F2R PDGFRB PDGFRB ARHGAP42 ARHGAP42 SIPA1L2 SIPA1L2 PSD PSD RAP1GAP RAP1GAP RALGPS2 RALGPS2 SIPA1L1 SIPA1L1 STMN3 STMN3 RASA2 RASA2 ARRB1 ARRB1 TGM2 TGM2 GPR35 GPR35 CRK CRK SYNGAP1 SYNGAP1 AMOT AMOT CSF1 CSF1 STARD13 STARD13 APOA1 APOA1 RIPOR3 RIPOR3 CYTH4 CYTH4 F2RL1 F2RL1 ARHGAP44 ARHGAP44 RAPGEF1 RAPGEF1 CUL3 CUL3 CYTH2 CYTH2 CAVIN4 CAVIN4 CDH2 CDH2 MAPKAP1 MAPKAP1 INF2 INF2 RALGAPA1 RALGAPA1 MAPRE2 MAPRE2 GPR4 GPR4 Arhgef25 Arhgef25 DENND4A DENND4A F2RL3 F2RL3 RGL2 RGL2 SIPA1 SIPA1 LZTR1 LZTR1 AUTS2 AUTS2 LOC104874341 LOC104874341 ICMT ICMT GPR65 GPR65 FRMD7 FRMD7 ARHGAP35 ARHGAP35 CGNL1 CGNL1 CHN1 CHN1 SLIT2 SLIT2 GBF1 GBF1 RALBP1 RALBP1 Chn2 Chn2 ABRA ABRA RASGRF2 RASGRF2 FLCN FLCN STARD8 STARD8 RABL3 RABL3 RASAL1 RASAL1 Psd4 Psd4 MYO9B MYO9B SCAI SCAI ARF6 ARF6 FBXO8 FBXO8 NRG1 NRG1 GIT2 GIT2 Akap13 Akap13 SPRY3 SPRY3 BCR BCR TNK1 TNK1 DENND4C DENND4C Rasip1 Rasip1 MET MET OPHN1 OPHN1 KCTD10 KCTD10 Nup62 Nup62 SYNPO2L SYNPO2L FAM13A FAM13A SHOC2 SHOC2 ARAP3 ARAP3 MMD2 MMD2 TSC2 TSC2 LPAR1 LPAR1 GPR55 GPR55 TNFAIP1 TNFAIP1 KITLG KITLG ITGA3 ITGA3 FOXM1 FOXM1 SPRY2 SPRY2 PIK3CG PIK3CG MCF2L MCF2L CDC42SE1 CDC42SE1 FGF10 FGF10 DAB2IP DAB2IP RASGRP1 RASGRP1 ENSFDAP00000009315 ENSFDAP00000009315 IQSEC2 IQSEC2 CYTH3 CYTH3 NET1 NET1 DENND1A DENND1A NRP1 NRP1 GPR17 GPR17 SOS2 SOS2 BNIP2 BNIP2 ARHGAP24 ARHGAP24 RIT2 RIT2 DYNLT1 DYNLT1 MFN2 MFN2 RASGEF1A RASGEF1A GPR18 GPR18 ABCA1 ABCA1 ARHGAP12 ARHGAP12 DGKZ DGKZ ARHGAP28 ARHGAP28 GIT1 GIT1 H920_04788 H920_04788 SIPA1L3 SIPA1L3 SPRY4 SPRY4 KANK1 KANK1 MYOC MYOC NTRK1 NTRK1 ITGAV ITGAV ARHGEF3 ARHGEF3 LOC104855160 LOC104855160 SH2B2 SH2B2 FBP1 FBP1 RALGAPB RALGAPB LPAR2 LPAR2 SOS1 SOS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RASA3Ras GTPase-activating protein 3. (801 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (512 aa)
NF1Neurofibromin. (2818 aa)
RALGPS1Ral GEF with PH domain and SH3 binding motif 1. (584 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (388 aa)
MADDMAP kinase activating death domain. (1595 aa)
NOTCH2Uncharacterized protein. (2418 aa)
CDC42SE2CDC42 small effector 2. (85 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1046 aa)
Eps8l3Epidermal growth factor receptor kinase substrate 8-like protein 3. (89 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (362 aa)
RASGRP4RAS guanyl-releasing protein 4. (652 aa)
ENSFDAP00000005046annotation not available (69 aa)
ARHGEF28Rho-guanine nucleotide exchange factor. (1592 aa)
TRIM67Tripartite motif-containing protein 67. (479 aa)
F11RJunctional adhesion molecule A. (299 aa)
Arhgap26Rho GTPase-activating protein 26. (171 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
DENND3DENN domain-containing protein 3. (1284 aa)
SYDE1Rho GTPase-activating protein SYDE1. (729 aa)
DLC1Rho GTPase-activating protein 7. (1526 aa)
Rtn4Reticulon. (199 aa)
CBLE3 ubiquitin-protein ligase CBL. (851 aa)
EPOErythropoietin. (198 aa)
ARFGAP1ADP ribosylation factor GTPase activating protein 1. (427 aa)
RALGAPA2Ral GTPase-activating protein subunit alpha-2. (1853 aa)
DENND4BDENN domain-containing protein 4B. (1429 aa)
HEG1Integrin beta; Belongs to the integrin beta chain family. (1141 aa)
SPRY1Protein sprouty like protein 1. (319 aa)
STMN1Stathmin; Belongs to the stathmin family. (149 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (957 aa)
CADM4Cell adhesion molecule 4. (366 aa)
CYTH1Cytohesin-1. (389 aa)
ARFGEF1Brefeldin A-inhibited guanine nucleotide-exchange protein 1. (1848 aa)
LRRC59Leucine-rich repeat-containing protein 59. (180 aa)
LRRD1Leucine-rich repeat and death domain-containing protein 1. (839 aa)
LOC104858674Ras GTPase-activating protein 4. (802 aa)
ABL1Tyrosine-protein kinase. (1012 aa)
ARHGAP17Rho GTPase-activating protein 17. (826 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
EPS8Epidermal growth factor receptor kinase substrate 8. (822 aa)
DGKIDiacylglycerol kinase. (968 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1325 aa)
EPHB2Ephrin type-B receptor 2. (1022 aa)
SSX2IPAfadin-and alpha-actinin-binding protein. (613 aa)
ADCYAP1R1Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family. (524 aa)
ARFGEF2Brefeldin A-inhibited guanine nucleotide-exchange protein 2. (1770 aa)
KCTD13Potassium channel tetramerization domain containing 13. (313 aa)
Eps8l1Epidermal growth factor receptor kinase substrate 8-like protein 1. (132 aa)
FAM49BProtein FAM49B. (324 aa)
RASGRF1Ras-specific guanine nucleotide-releasing factor 1. (1252 aa)
SGSM3Small G protein signaling modulator 3. (747 aa)
SYDE2Rho GTPase-activating protein SYDE2. (875 aa)
DNM2Dynamin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (791 aa)
RAB3GAP1Rab3 GTPase-activating protein catalytic subunit. (987 aa)
IGF1Insulin-like growth factor I. (158 aa)
ARHGDIARho GDP-dissociation inhibitor 1. (204 aa)
ARHGAP18Rho GTPase-activating protein 18. (667 aa)
Rap1gap2Rap1 GTPase-activating protein 2. (712 aa)
TGFB2Transforming growth factor beta 2. (398 aa)
LOC104862775Rab5 GDP/GTP exchange factor. (491 aa)
CD2APCD2-associated protein. (636 aa)
IQSEC3IQ motif and Sec7 domain ArfGEF 3. (985 aa)
ARHGAP25Rho GTPase-activating protein 25. (645 aa)
COL3A1Collagen alpha-1(III) chain. (1463 aa)
KIAA1755KIAA1755 ortholog. (1197 aa)
PSD2PH and SEC7 domain-containing protein 2. (770 aa)
Arhgap19Rho GTPase-activating protein 19. (477 aa)
ADGRG1G-protein coupled receptor 56; Belongs to the G-protein coupled receptor 2 family. (668 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (800 aa)
ARHGDIBRho GDP-dissociation inhibitor 2. (174 aa)
GARNL3GTPase-activating Rap/Ran-GAP domain-like protein 3. (1040 aa)
FLOT1Flotillin 1. (380 aa)
ABL2Tyrosine-protein kinase. (1138 aa)
IQSEC1IQ motif and SEC7 domain-containing protein 1. (925 aa)
ROBO1Roundabout like protein 1. (1684 aa)
PLCE1Phosphoinositide phospholipase C. (2298 aa)
APOEApolipoprotein E. (228 aa)
H920_09510Reelin. (279 aa)
BCL6B-cell lymphoma 6 protein. (688 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1258 aa)
PSD3PH and SEC7 domain-containing protein 3. (1060 aa)
MAP4K4TRAF2 and NCK-interacting protein kinase. (1272 aa)
RIPOR2Protein FAM65B. (1040 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (803 aa)
RTN4RReticulon 4 receptor. (465 aa)
Sh3bp1SH3 domain-binding protein 1. (692 aa)
EPS8L2Epidermal growth factor receptor kinase substrate 8-like protein 2. (710 aa)
ARFGEF3Brefeldin A-inhibited guanine nucleotide-exchange protein 3. (2109 aa)
RASA1Ras GTPase-activating protein 1. (893 aa)
RELNReelin. (2792 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (403 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1097 aa)
ARHGAP42Rho GTPase-activating protein 42. (874 aa)
SIPA1L2Signal-induced proliferation-associated 1-like protein 2. (1722 aa)
PSDPH and SEC7 domain-containing protein 1. (987 aa)
RAP1GAPRAP1 GTPase activating protein. (663 aa)
RALGPS2Ras-specific guanine nucleotide-releasing factor RalGPS2. (583 aa)
SIPA1L1Signal-induced proliferation-associated 1-like protein 1. (1804 aa)
STMN3Stathmin; Belongs to the stathmin family. (109 aa)
RASA2Ras GTPase-activating protein 2. (791 aa)
ARRB1Beta-arrestin-1. (418 aa)
TGM2Transglutaminase 2. (691 aa)
GPR35G-protein coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (306 aa)
CRKCRK proto-oncogene, adaptor protein. (247 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1295 aa)
AMOTAngiomotin. (1069 aa)
CSF1Colony stimulating factor 1. (527 aa)
STARD13StAR-related lipid transfer protein 13. (1112 aa)
APOA1Apolipoprotein A1. (264 aa)
RIPOR3Protein FAM65C. (950 aa)
CYTH4Cytohesin-4. (394 aa)
F2RL1Proteinase-activated receptor 2. (370 aa)
ARHGAP44Rho GTPase-activating protein 44. (822 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1211 aa)
CUL3Cullin-3; Belongs to the cullin family. (770 aa)
CYTH2Cytohesin-2. (393 aa)
CAVIN4Muscle-related coiled-coil protein. (362 aa)
CDH2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (886 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
INF2Inverted formin, FH2 and WH2 domain containing. (1184 aa)
RALGAPA1Ral GTPase-activating protein subunit alpha-1. (2000 aa)
MAPRE2Microtubule-associated protein RP/EB family member 2. (357 aa)
GPR4G-protein coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
Arhgef25Rho guanine nucleotide exchange factor 25. (618 aa)
DENND4ADENN domain containing 4A. (1907 aa)
F2RL3Proteinase-activated receptor 4; Belongs to the G-protein coupled receptor 1 family. (387 aa)
RGL2Ral guanine nucleotide dissociation stimulator-like 2. (721 aa)
SIPA1Signal-induced proliferation-associated protein 1. (1025 aa)
LZTR1Leucine-zipper-like transcriptional regulator 1. (839 aa)
AUTS2Autism susceptibility gene 2 protein. (763 aa)
LOC104874341Putative P2Y purinoceptor 10. (103 aa)
ICMTProtein-S-isoprenylcysteine O-methyltransferase. (278 aa)
GPR65Psychosine receptor; Belongs to the G-protein coupled receptor 1 family. (334 aa)
FRMD7FERM domain-containing protein 7. (704 aa)
ARHGAP35Rho GTPase activating protein 35. (1522 aa)
CGNL1Cingulin-like protein 1. (1187 aa)
CHN1N-chimaerin. (458 aa)
SLIT2Slit like protein 2 protein. (1542 aa)
GBF1Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1. (1851 aa)
RALBP1RalA-binding protein 1. (567 aa)
Chn2Beta-chimaerin. (462 aa)
ABRAActin-binding Rho-activating protein. (369 aa)
RASGRF2Creatine kinase S-type, mitochondrial. (1179 aa)
FLCNFolliculin. (579 aa)
STARD8StAR-related lipid transfer protein 8. (1016 aa)
RABL3Rab-like protein 3. (235 aa)
RASAL1RasGAP-activating-like protein 1. (755 aa)
Psd4PH and SEC7 domain-containing protein 4. (65 aa)
MYO9BMyosin IXB. (1632 aa)
SCAIProtein SCAI. (590 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
FBXO8F-box only protein 8. (319 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform. (699 aa)
GIT2ARF GTPase-activating protein GIT2. (758 aa)
Akap13A-kinase anchor protein 13. (1430 aa)
SPRY3Protein sprouty like protein 3. (288 aa)
BCRBreakpoint cluster region protein. (1221 aa)
TNK1Non-receptor tyrosine-protein kinase TNK1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (662 aa)
DENND4CDENN domain-containing protein 4C. (1969 aa)
Rasip1Ras-interacting protein 1. (318 aa)
METHepatocyte growth factor receptor. (1382 aa)
OPHN1Oligophrenin-1. (802 aa)
KCTD10BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3. (315 aa)
Nup62Nucleoporin 62. (40 aa)
SYNPO2LSynaptopodin 2-like protein. (970 aa)
FAM13AProtein FAM13A. (1036 aa)
SHOC2Leucine-rich repeat protein SHOC-2. (582 aa)
ARAP3Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3. (1541 aa)
MMD2Monocyte to macrophage differentiation factor 2. (246 aa)
TSC2Tuberin. (1743 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
GPR55G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (359 aa)
TNFAIP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2. (316 aa)
KITLGKit ligand. (272 aa)
ITGA3Integrin alpha-3; Belongs to the integrin alpha chain family. (1000 aa)
FOXM1Forkhead box protein M1. (763 aa)
SPRY2Protein sprouty like protein 2. (315 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1095 aa)
MCF2LGuanine nucleotide exchange factor DBS. (1121 aa)
CDC42SE1CDC42 small effector 1. (79 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
DAB2IPDisabled like protein 2-interacting protein. (1161 aa)
RASGRP1RAS guanyl-releasing protein 1. (796 aa)
ENSFDAP00000009315annotation not available (117 aa)
IQSEC2IQ motif and Sec7 domain ArfGEF 2. (1227 aa)
CYTH3Cytohesin-3. (387 aa)
NET1Neuroepithelial cell-transforming gene 1 protein. (553 aa)
DENND1ADENN domain-containing protein 1A. (999 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (898 aa)
GPR17Uracil nucleotide/cysteinyl leukotriene receptor; Belongs to the G-protein coupled receptor 1 family. (338 aa)
SOS2Son of sevenless like protein 2. (1310 aa)
BNIP2BCL2/adenovirus E1B 19 kDa protein-interacting protein 2. (335 aa)
ARHGAP24Rho GTPase-activating protein 24. (749 aa)
RIT2GTP-binding protein Rit2. (217 aa)
DYNLT1Dynein light chain Tctex-type 1. (113 aa)
MFN2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (762 aa)
RASGEF1ARas-GEF domain-containing family member 1A. (479 aa)
GPR18N-arachidonyl glycine receptor. (335 aa)
ABCA1ATP-binding cassette sub-family A member 1. (2119 aa)
ARHGAP12Rho GTPase-activating protein 12. (846 aa)
DGKZDiacylglycerol kinase zeta. (998 aa)
ARHGAP28Rho GTPase-activating protein 28. (661 aa)
GIT1ARF GTPase-activating protein GIT1. (770 aa)
H920_04788Beta-chimaerin. (232 aa)
SIPA1L3Signal-induced proliferation-associated 1-like protein 3. (1793 aa)
SPRY4Protein sprouty like protein 4. (300 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1. (1349 aa)
MYOCMyocilin. (489 aa)
NTRK1Tyrosine-protein kinase receptor. (727 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (558 aa)
LOC104855160Rho GTPase-activating protein 26. (451 aa)
SH2B2SH2B adapter protein 2. (515 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (337 aa)
RALGAPBRal GTPase activating protein non-catalytic beta subunit. (1507 aa)
LPAR2Lysophosphatidic acid receptor 2. (319 aa)
SOS1Son of sevenless like protein 1. (1289 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
Server load: low (16%) [HD]