STRINGSTRING
ALPL ALPL RARG RARG COL10A1 COL10A1 Ebp Ebp Atg9a Atg9a TP53 TP53 FOXN3 FOXN3 FGF18 FGF18 Sbds Sbds LTF LTF GLI3 GLI3 LOC104865308 LOC104865308 COL27A1 COL27A1 SIK3 SIK3 CCN4 CCN4 LEPR LEPR WASF2 WASF2 FGFR2 FGFR2 MED1 MED1 MAPK11 MAPK11 Zfpm1 Zfpm1 SRD5A2 SRD5A2 SPARC SPARC LOC104865357 LOC104865357 FAM20C FAM20C WNT1 WNT1 BGLAP BGLAP TTC9 TTC9 OPA3 OPA3 BGN BGN MEGF8 MEGF8 BMP6 BMP6 OGN OGN SMAD5 SMAD5 IMPAD1 IMPAD1 PEX7 PEX7 MATN1 MATN1 COMP COMP INSIG2 INSIG2 HAS2 HAS2 STC1 STC1 XYLT1 XYLT1 IFT80 IFT80 PLXNB1 PLXNB1 MAP2K6 MAP2K6 BBX BBX MYOC MYOC INPPL1 INPPL1 ANKRD11 ANKRD11 CER1 CER1 FBLN5 FBLN5 MSX2 MSX2 ACP5 ACP5 CHAD CHAD SKI SKI Adamts12 Adamts12 KIT KIT THBS3 THBS3 PHOSPHO2 PHOSPHO2 RAB23 RAB23 EP300 EP300 ENPP1 ENPP1 PDGFA PDGFA ZMPSTE24 ZMPSTE24 TMEM107 TMEM107 SMAD1 SMAD1 MAPK14 MAPK14 HSPG2 HSPG2 LEP LEP Smad9 Smad9 Fgf4 Fgf4 ADAMTS7 ADAMTS7 TRPV4 TRPV4 CHSY1 CHSY1 NPR2 NPR2 DYM DYM PAFAH1B1 PAFAH1B1 PIP4K2A PIP4K2A TMEM38B TMEM38B BMPR1B BMPR1B IFT172 IFT172 SOX9 SOX9 MEIS1 MEIS1 EXT1 EXT1 SEMA4D SEMA4D NBEAL2 NBEAL2 TGFBR2 TGFBR2 RARA RARA PLS3 PLS3 ACTN3 ACTN3 Foxp1 Foxp1 MMP13 MMP13 H920_19388 H920_19388 NSD2 NSD2 BMP2 BMP2 POC1A POC1A Anxa2 Anxa2 ATP6AP1 ATP6AP1 CYP26B1 CYP26B1 PITX2 PITX2 LRRC17 LRRC17 Cbs Cbs RIPPLY2 RIPPLY2 COL2A1 COL2A1 LRP5 LRP5 CCDC154 CCDC154 DCHS1 DCHS1 SNX10 SNX10 IFITM5 IFITM5 PTPN11 PTPN11 H920_08154 H920_08154 IGF1 IGF1 EXT2 EXT2 ANXA6 ANXA6 SH3PXD2B SH3PXD2B SCUBE2 SCUBE2 ZNF385A ZNF385A PTGER4 PTGER4 EPYC EPYC VKORC1 VKORC1 COL1A1 COL1A1 PHEX PHEX SLC38A10 SLC38A10 OSR2 OSR2 SLC10A7 SLC10A7 SHOX2 SHOX2 SULF2 SULF2 RARB RARB PDGFC PDGFC OSTN OSTN ECM1 ECM1 PPIB PPIB TNFSF11 TNFSF11 GLG1 GLG1 TBXT TBXT PAPPA2 PAPPA2 SH2B3 SH2B3 SCX SCX TRIM45 TRIM45 TULP3 TULP3 FGFR3 FGFR3 GP1BA GP1BA FGF8 FGF8 Vps33b Vps33b BNC2 BNC2 PRPSAP2 PRPSAP2 ATF2 ATF2 TGM2 TGM2 H920_07124 H920_07124 RYR1 RYR1 SFRP4 SFRP4 BMP4 BMP4 H920_17555 H920_17555 TRIP11 TRIP11 SETDB1 SETDB1 MEF2C MEF2C KDR KDR PAPSS2 PAPSS2 COL3A1 COL3A1 SMPD3 SMPD3 CTC1 CTC1 LRRK1 LRRK1 MMP16 MMP16 ZBTB16 ZBTB16 CSGALNACT1 CSGALNACT1 CARM1 CARM1 HOXA11 HOXA11 H920_03634 H920_03634 BMPR2 BMPR2 ITGB6 ITGB6 ADAMTS12 ADAMTS12 DLX5 DLX5 P3H1 P3H1 MIGA2 MIGA2 SERPINH1 SERPINH1 PAX1 PAX1 TFAP2A TFAP2A IHH IHH RUNX2 RUNX2 MEF2D MEF2D IDUA IDUA NOTUM NOTUM Thpo Thpo INSIG1 INSIG1 ABI1 ABI1 CITED2 CITED2 SULF1 SULF1 SRF SRF ENSFDAP00000022977 ENSFDAP00000022977 PTPRC PTPRC ANO6 ANO6 MAP3K7 MAP3K7 ENG ENG SPNS2 SPNS2 THBS1 THBS1 LOC104850622 LOC104850622 RANBP3L RANBP3L TGFB3 TGFB3 FLI1 FLI1 DDR2 DDR2 NPPC NPPC Col9a1 Col9a1 CADM1 CADM1 NEUROG1 NEUROG1 LTBP3 LTBP3 FAT4 FAT4 AXIN2 AXIN2 DHRS3 DHRS3 MBTPS2 MBTPS2 AMER1 AMER1 GPR68 GPR68 Akap13 Akap13 SRD5A1 SRD5A1 PTPN6 PTPN6 MMP14 MMP14 COL13A1 COL13A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALPLAlkaline phosphatase. (531 aa)
RARGRetinoic acid receptor gamma. (462 aa)
COL10A1Collagen alpha-1(X) chain. (680 aa)
Ebp3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase. (231 aa)
Atg9aAutophagy-related protein 9A. (839 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
FOXN3Forkhead box protein N3. (485 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SbdsRibosome maturation protein SBDS. (250 aa)
LTFLactotransferrin; Belongs to the transferrin family. (715 aa)
GLI3Transcriptional activator GLI3. (1570 aa)
LOC104865308Neuroendocrine secretory protein 55. (229 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1609 aa)
SIK3Serine/threonine-protein kinase SIK3. (1278 aa)
CCN4WNT1-inducible-signaling pathway protein 1. (287 aa)
LEPRLeptin receptor. (1165 aa)
WASF2Wiskott-Aldrich syndrome protein family member 2. (485 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1568 aa)
MAPK11Mitogen-activated protein kinase 11. (325 aa)
Zfpm1Zinc finger protein 469. (551 aa)
SRD5A2Steroid 5 alpha-reductase 2. (254 aa)
SPARCSPARC. (304 aa)
LOC104865357Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas. (347 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (464 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (96 aa)
TTC9Tetratricopeptide repeat protein 9A. (184 aa)
OPA3Outer mitochondrial membrane lipid metabolism regulator OPA3. (170 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (368 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2809 aa)
BMP6Bone morphogenetic protein 6. (319 aa)
OGNMimecan. (295 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
IMPAD1Inositol monophosphatase 3. (298 aa)
PEX7Peroxisomal targeting signal 2 receptor. (301 aa)
MATN1Cartilage matrix protein. (496 aa)
COMPCartilage oligomeric matrix protein. (712 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
HAS2Hyaluronan synthase 2. (552 aa)
STC1Stanniocalcin-1. (247 aa)
XYLT1Xylosyltransferase 1. (838 aa)
IFT80Intraflagellar transport protein 80 like protein. (777 aa)
PLXNB1Plexin-B1. (2135 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
BBXHMG box transcription factor BBX. (909 aa)
MYOCMyocilin. (489 aa)
INPPL1Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2. (1225 aa)
ANKRD11Ankyrin repeat domain-containing protein 11. (2650 aa)
CER1Cerberus. (267 aa)
FBLN5Fibulin-5. (448 aa)
MSX2Homeobox protein MSX-2. (268 aa)
ACP5Acid phosphatase 5, tartrate resistant. (327 aa)
CHADChondroadherin. (348 aa)
SKISki oncogene. (704 aa)
Adamts12A disintegrin and metalloproteinase with thrombospondin motifs 12. (178 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (955 aa)
THBS3Thrombospondin-3. (956 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
RAB23Ras-related protein Rab-23. (237 aa)
EP300Histone acetyltransferase p300. (2430 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (873 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (207 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
TMEM107Transmembrane protein 107. (140 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
HSPG2Basement membrane-specific heparan sulfate proteoglycan core protein. (4246 aa)
LEPLeptin. (167 aa)
Smad9Mothers against decapentaplegic homolog. (430 aa)
Fgf4Fibroblast growth factor 4. (52 aa)
ADAMTS7A disintegrin and metalloproteinase with thrombospondin motifs 7. (1529 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
CHSY1Hexosyltransferase. (695 aa)
NPR2Guanylate cyclase. (1047 aa)
DYMDymeclin. (669 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type-2 alpha. (358 aa)
TMEM38BTrimeric intracellular cation channel type B. (236 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
IFT172Intraflagellar transport protein 172 like protein. (1747 aa)
SOX9Transcription factor Sox-9-B. (430 aa)
MEIS1Homeobox protein Meis2. (465 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
SEMA4DSemaphorin-4D; Belongs to the semaphorin family. (862 aa)
NBEAL2Neurobeachin like 2. (2703 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (560 aa)
RARARetinoic acid receptor alpha. (421 aa)
PLS3Plastin-3. (639 aa)
ACTN3Alpha-actinin-3. (900 aa)
Foxp1Forkhead box protein P1. (708 aa)
MMP13Collagenase 3. (471 aa)
H920_19388TRAF-interacting protein with FHA domain-containing protein B. (250 aa)
NSD2Putative histone-lysine N-methyltransferase NSD2. (1366 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
POC1APOC1 centriolar protein like protein A. (407 aa)
Anxa2Annexin. (339 aa)
ATP6AP1V-type proton ATPase subunit S1. (459 aa)
CYP26B1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (480 aa)
PITX2Homeobox protein. (255 aa)
LRRC17Leucine rich repeat containing 17. (442 aa)
CbsCystathionine beta-synthase. (515 aa)
RIPPLY2Ripply transcriptional repressor 2. (107 aa)
COL2A1Collagen alpha-1(II) chain. (1487 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1645 aa)
CCDC154Coiled-coil domain-containing protein 154. (632 aa)
DCHS1Protocadherin-16. (3195 aa)
SNX10Sorting nexin-10. (201 aa)
IFITM5Interferon-induced transmembrane protein 5. (134 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (600 aa)
H920_08154FRAS1-related extracellular matrix protein 1. (1326 aa)
IGF1Insulin-like growth factor I. (158 aa)
EXT2Exostosin-2; Belongs to the glycosyltransferase 47 family. (717 aa)
ANXA6Annexin. (646 aa)
SH3PXD2BSH3 and PX domain-containing protein 2B. (882 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2. (954 aa)
ZNF385AZinc finger protein 385A. (382 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (492 aa)
EPYCEpiphycan. (325 aa)
VKORC1Vitamin K epoxide reductase complex subunit 1. (163 aa)
COL1A1Collagen alpha-1(I) chain. (1453 aa)
PHEXMetalloendopeptidase like protein PEX. (749 aa)
SLC38A10Putative sodium-coupled neutral amino acid transporter 10. (1086 aa)
OSR2Protein odd-skipped-related 2. (276 aa)
SLC10A7Sodium/bile acid cotransporter 7. (340 aa)
SHOX2Short stature homeobox 2. (270 aa)
SULF2Extracellular sulfatase Sulf-2. (871 aa)
RARBRetinoic acid receptor beta. (448 aa)
PDGFCPlatelet-derived growth factor C. (305 aa)
OSTNOsteocrin. (132 aa)
ECM1Extracellular matrix protein 1. (560 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (208 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (287 aa)
GLG1Golgi apparatus protein 1. (1184 aa)
TBXTBrachyury protein. (436 aa)
PAPPA2Pappalysin-2. (1789 aa)
SH2B3SH2B adapter protein 3. (343 aa)
SCXScleraxis bHLH transcription factor. (129 aa)
TRIM45Tripartite motif-containing protein 45. (580 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (449 aa)
FGFR3Fibroblast growth factor receptor 3. (748 aa)
GP1BAPlatelet glycoprotein Ib alpha chain. (672 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
Vps33bVacuolar protein sorting-associated protein 33B. (617 aa)
BNC2Zinc finger protein basonuclin-2. (1154 aa)
PRPSAP2Phosphoribosyl pyrophosphate synthase-associated protein 2. (369 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (505 aa)
TGM2Transglutaminase 2. (691 aa)
H920_07124Putative Polycomb group protein ASXL1. (86 aa)
RYR1Ryanodine receptor 1. (4870 aa)
SFRP4Secreted frizzled-related protein 4. (316 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
H920_17555Protein G6b. (122 aa)
TRIP11Thyroid receptor-interacting protein 11. (1960 aa)
SETDB1Histone-lysine N-methyltransferase SETDB1. (1291 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1346 aa)
PAPSS2Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2. (620 aa)
COL3A1Collagen alpha-1(III) chain. (1463 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (569 aa)
CTC1CST complex subunit CTC1. (1171 aa)
LRRK1Leucine-rich repeat serine/threonine-protein kinase 1. (2015 aa)
MMP16Matrix metalloproteinase-16. (607 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16. (676 aa)
CSGALNACT1Hexosyltransferase. (528 aa)
CARM1Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (558 aa)
HOXA11Homeobox protein Hox-D11. (314 aa)
H920_03634Homeobox protein Hox-B4. (146 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1025 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (807 aa)
ADAMTS12A disintegrin and metalloproteinase with thrombospondin motifs 12. (1388 aa)
DLX5Homeobox protein DLX-5. (289 aa)
P3H1Prolyl 3-hydroxylase 1. (715 aa)
MIGA2Protein FAM73B. (548 aa)
SERPINH1Serpin H1; Belongs to the serpin family. (418 aa)
PAX1Paired box protein Pax-1. (362 aa)
TFAP2ATranscription factor AP-2 alpha. (382 aa)
IHHIndian hedgehog signaling molecule. (370 aa)
RUNX2Runt-related transcription factor 2. (508 aa)
MEF2DMyocyte-specific enhancer factor 2D. (483 aa)
IDUAAlpha-L-iduronidase. (457 aa)
NOTUMProtein notum like protein. (453 aa)
ThpoThrombopoietin. (319 aa)
INSIG1Insulin induced gene 1. (255 aa)
ABI1Abl interactor 1. (470 aa)
CITED2Cbp/p300-interacting transactivator 2. (220 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
SRFSerum response factor. (337 aa)
ENSFDAP00000022977annotation not available (183 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C. (1146 aa)
ANO6Anoctamin. (910 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (606 aa)
ENGEndoglin. (557 aa)
SPNS2Sphingolipid transporter 2. (448 aa)
THBS1Thrombospondin-1. (1181 aa)
LOC104850622Guanine nucleotide-binding protein G(S) subunit alpha. (394 aa)
RANBP3LRAN binding protein 3 like. (486 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
FLI1Friend leukemia integration 1 transcription factor. (452 aa)
DDR2Discoidin domain-containing receptor 2. (882 aa)
NPPCC-type natriuretic peptide. (126 aa)
Col9a1Collagen alpha-1(IX) chain. (910 aa)
CADM1Cell adhesion molecule 1. (432 aa)
NEUROG1Neurogenin-1. (241 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3. (1131 aa)
FAT4Protocadherin Fat 4. (4984 aa)
AXIN2Axin-2. (860 aa)
DHRS3Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
MBTPS2Membrane-bound transcription factor site-2 protease. (517 aa)
AMER1Protein FAM123B. (1123 aa)
GPR68Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
Akap13A-kinase anchor protein 13. (1430 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase 1. (197 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
MMP14Matrix metallopeptidase 14. (546 aa)
COL13A1Collagen alpha-1(XIII) chain. (631 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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