STRINGSTRING
BCDIN3D BCDIN3D TGFB1 TGFB1 NCOR1 NCOR1 HNF1A HNF1A ELAVL1 ELAVL1 ZMPSTE24 ZMPSTE24 TNF TNF Ajuba Ajuba EGFR EGFR NCOR2 NCOR2 MAEL MAEL Map2k2 Map2k2 ZC3H10 ZC3H10 DND1 DND1 DHX9 DHX9 PUM1 PUM1 Mecp2 Mecp2 TIAL1 TIAL1 PPARG PPARG STAT3 STAT3 LIN28B LIN28B NFKB1 NFKB1 Wtip Wtip BMP4 BMP4 ZFP36 ZFP36 TRUB1 TRUB1 Limd1 Limd1 FXR1 FXR1 PUM2 PUM2 TRIM71 TRIM71 Ddx5 Ddx5 PPP3CA PPP3CA TP53 TP53 RIPK1 RIPK1 ENSFDAP00000009586 ENSFDAP00000009586 FMR1 FMR1 ZC3H12A ZC3H12A LIN28A LIN28A MAP2K1 MAP2K1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCDIN3DPutative methyltransferase BCDIN3D. (293 aa)
TGFB1Transforming growth factor beta-1. (333 aa)
NCOR1Nuclear receptor corepressor 1. (2434 aa)
HNF1AHepatocyte nuclear factor 1-alpha. (631 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
AjubaProtein ajuba. (121 aa)
EGFRReceptor protein-tyrosine kinase. (1168 aa)
NCOR2Nuclear receptor corepressor 2. (2399 aa)
MAELProtein maelstrom like protein. (411 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (370 aa)
ZC3H10Zinc finger CCCH-type containing 10. (435 aa)
DND1DND microRNA-mediated repression inhibitor 1. (274 aa)
DHX9ATP-dependent RNA helicase A. (1368 aa)
PUM1Pumilio like protein 1. (1189 aa)
Mecp2methyl-CpG binding protein 2. (172 aa)
TIAL1Nucleolysin TIAR. (385 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
STAT3Signal transducer and activator of transcription. (758 aa)
LIN28BProtein lin-28 like protein B. (250 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (894 aa)
WtipWilms tumor protein 1-interacting protein. (206 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
ZFP36Tristetraprolin. (315 aa)
TRUB1TruB pseudouridine synthase family member 1. (244 aa)
Limd1LIM domains containing 1. (405 aa)
FXR1Fragile X mental retardation syndrome-related protein 1. (678 aa)
PUM2Pumilio like protein 2. (1068 aa)
TRIM71Tripartite motif containing 71. (661 aa)
Ddx5Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (600 aa)
PPP3CASerine/threonine-protein phosphatase. (501 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (660 aa)
ENSFDAP00000009586annotation not available (571 aa)
FMR1FMRP translational regulator 1. (622 aa)
ZC3H12ARibonuclease ZC3H12A. (595 aa)
LIN28AProtein lin-28 like protein A. (209 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (388 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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