(26 nodes) Positive regulation of cartilage development network (Fukomys damarensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HOXA11	Homeobox protein Hox-D11. (314 aa)
	LOXL2	Lysyl oxidase like protein 2. (775 aa)
	RUNX2	Runt-related transcription factor 2. (508 aa)
	BMPR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1025 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	ZNF219	Zinc finger protein 219. (703 aa)
	Mustn1	Musculoskeletal embryonic nuclear protein 1. (81 aa)
	SOX9	Transcription factor Sox-9-B. (430 aa)
	SMAD3	Mothers against decapentaplegic homolog. (429 aa)
	PKDCC	Protein kinase domain-containing protein, cytoplasmic. (294 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	SOX6	Transcription factor SOX-6. (828 aa)
	BMP6	Bone morphogenetic protein 6. (319 aa)
	BMP1	Metalloendopeptidase. (935 aa)
	CCN1	Protein CYR61. (381 aa)
	SMAD7	Mothers against decapentaplegic homolog. (229 aa)
	GDF5	Growth differentiation factor 5. (495 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	GLI3	Transcriptional activator GLI3. (1570 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
	GDF2	Bone morphogenetic protein 3B. (417 aa)
	SCX	Scleraxis bHLH transcription factor. (129 aa)
	BMP4	Bone morphogenetic protein 4. (410 aa)
	ZBTB16	Zinc finger and BTB domain-containing protein 16. (676 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP1	BMP2	ENSFDAP00000008860	ENSFDAP00000001763	Metalloendopeptidase.	Bone morphogenetic protein 2.	0.616
BMP1	BMP4	ENSFDAP00000008860	ENSFDAP00000019587	Metalloendopeptidase.	Bone morphogenetic protein 4.	0.479
BMP1	LOXL2	ENSFDAP00000008860	ENSFDAP00000000914	Metalloendopeptidase.	Lysyl oxidase like protein 2.	0.431
BMP10	BMP2	ENSFDAP00000010357	ENSFDAP00000001763	Bone morphogenetic protein 10.	Bone morphogenetic protein 2.	0.422
BMP10	BMP4	ENSFDAP00000010357	ENSFDAP00000019587	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.445
BMP10	BMP6	ENSFDAP00000010357	ENSFDAP00000008786	Bone morphogenetic protein 10.	Bone morphogenetic protein 6.	0.409
BMP10	BMPR2	ENSFDAP00000010357	ENSFDAP00000021375	Bone morphogenetic protein 10.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.993
BMP10	GDF2	ENSFDAP00000010357	ENSFDAP00000017451	Bone morphogenetic protein 10.	Bone morphogenetic protein 3B.	0.744
BMP10	GDF5	ENSFDAP00000010357	ENSFDAP00000009938	Bone morphogenetic protein 10.	Growth differentiation factor 5.	0.530
BMP10	SMAD1	ENSFDAP00000010357	ENSFDAP00000005398	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.448
BMP10	SMAD3	ENSFDAP00000010357	ENSFDAP00000005300	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.419
BMP10	SMAD7	ENSFDAP00000010357	ENSFDAP00000009760	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.447
BMP2	BMP1	ENSFDAP00000001763	ENSFDAP00000008860	Bone morphogenetic protein 2.	Metalloendopeptidase.	0.616
BMP2	BMP10	ENSFDAP00000001763	ENSFDAP00000010357	Bone morphogenetic protein 2.	Bone morphogenetic protein 10.	0.422
BMP2	BMP4	ENSFDAP00000001763	ENSFDAP00000019587	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.930
BMP2	BMP6	ENSFDAP00000001763	ENSFDAP00000008786	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.911
BMP2	BMPR2	ENSFDAP00000001763	ENSFDAP00000021375	Bone morphogenetic protein 2.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.978
BMP2	FGF18	ENSFDAP00000001763	ENSFDAP00000011514	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.424
BMP2	GDF2	ENSFDAP00000001763	ENSFDAP00000017451	Bone morphogenetic protein 2.	Bone morphogenetic protein 3B.	0.445
BMP2	GDF5	ENSFDAP00000001763	ENSFDAP00000009938	Bone morphogenetic protein 2.	Growth differentiation factor 5.	0.838