(13 nodes) Positive regulation of mucus secretion network (Fukomys damarensis)

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Your Input:
	ENSFDAP00000007466	annotation not available (44 aa)
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (699 aa)
	Atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (198 aa)
	PTGER4	Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (492 aa)
	Map1lc3b	Microtubule associated protein 1 light chain 3 beta. (112 aa)
	ENSFDAP00000017826	annotation not available (133 aa)
	P2RY2	p2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	ALOX12B	Arachidonate 12-lipoxygenase, 12R-type. (701 aa)
	SYTL2	Synaptotagmin like 2. (948 aa)
	PRKCE	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (736 aa)
	ADORA3	Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (319 aa)
	EGFR	Receptor protein-tyrosine kinase. (1168 aa)
	CYBA	Cytochrome b-245 light chain. (170 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG7	Atg5	ENSFDAP00000008688	ENSFDAP00000013584	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy protein 5; Involved in autophagic vesicle formation.	0.960
ATG7	ENSFDAP00000007466	ENSFDAP00000008688	ENSFDAP00000007466	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	annotation not available	0.960
ATG7	ENSFDAP00000017826	ENSFDAP00000008688	ENSFDAP00000017826	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	annotation not available	0.960
ATG7	Map1lc3b	ENSFDAP00000008688	ENSFDAP00000017960	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Microtubule associated protein 1 light chain 3 beta.	0.963
Atg5	ATG7	ENSFDAP00000013584	ENSFDAP00000008688	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.960
Atg5	ENSFDAP00000017826	ENSFDAP00000013584	ENSFDAP00000017826	Autophagy protein 5; Involved in autophagic vesicle formation.	annotation not available	0.895
Atg5	Map1lc3b	ENSFDAP00000013584	ENSFDAP00000017960	Autophagy protein 5; Involved in autophagic vesicle formation.	Microtubule associated protein 1 light chain 3 beta.	0.821
CYBA	PRKCE	ENSFDAP00000000556	ENSFDAP00000004267	Cytochrome b-245 light chain.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.640
EGFR	PRKCE	ENSFDAP00000003693	ENSFDAP00000004267	Receptor protein-tyrosine kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.418
ENSFDAP00000007466	ATG7	ENSFDAP00000007466	ENSFDAP00000008688	annotation not available	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.960
ENSFDAP00000007466	Map1lc3b	ENSFDAP00000007466	ENSFDAP00000017960	annotation not available	Microtubule associated protein 1 light chain 3 beta.	0.821
ENSFDAP00000017826	ATG7	ENSFDAP00000017826	ENSFDAP00000008688	annotation not available	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.960
ENSFDAP00000017826	Atg5	ENSFDAP00000017826	ENSFDAP00000013584	annotation not available	Autophagy protein 5; Involved in autophagic vesicle formation.	0.895
ENSFDAP00000017826	Map1lc3b	ENSFDAP00000017826	ENSFDAP00000017960	annotation not available	Microtubule associated protein 1 light chain 3 beta.	0.821
Map1lc3b	ATG7	ENSFDAP00000017960	ENSFDAP00000008688	Microtubule associated protein 1 light chain 3 beta.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.963
Map1lc3b	Atg5	ENSFDAP00000017960	ENSFDAP00000013584	Microtubule associated protein 1 light chain 3 beta.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.821
Map1lc3b	ENSFDAP00000007466	ENSFDAP00000017960	ENSFDAP00000007466	Microtubule associated protein 1 light chain 3 beta.	annotation not available	0.821
Map1lc3b	ENSFDAP00000017826	ENSFDAP00000017960	ENSFDAP00000017826	Microtubule associated protein 1 light chain 3 beta.	annotation not available	0.821
PRKCE	CYBA	ENSFDAP00000004267	ENSFDAP00000000556	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Cytochrome b-245 light chain.	0.640
PRKCE	EGFR	ENSFDAP00000004267	ENSFDAP00000003693	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Receptor protein-tyrosine kinase.	0.418