(8 nodes) BRCA1-A complex network (Fukomys damarensis)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	BRCA1	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1737 aa)
	Brcc3	Lys-63-specific deubiquitinase BRCC36. (288 aa)
	Babam1	BRISC and BRCA1 A complex member 1. (293 aa)
	ABRAXAS1	BRCA1-A complex subunit Abraxas. (359 aa)
	ENSFDAP00000001970	annotation not available (234 aa)
	BARD1	BRCA1-associated RING domain protein 1. (672 aa)
	BABAM2	BRISC and BRCA1 A complex member 2. (409 aa)
	H920_04415	BRCA1-A complex subunit RAP80. (415 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABRAXAS1	BABAM2	ENSFDAP00000003313	ENSFDAP00000013136	BRCA1-A complex subunit Abraxas.	BRISC and BRCA1 A complex member 2.	0.995
ABRAXAS1	BARD1	ENSFDAP00000003313	ENSFDAP00000018225	BRCA1-A complex subunit Abraxas.	BRCA1-associated RING domain protein 1.	0.994
ABRAXAS1	BRCA1	ENSFDAP00000003313	ENSFDAP00000004478	BRCA1-A complex subunit Abraxas.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.996
ABRAXAS1	Babam1	ENSFDAP00000003313	ENSFDAP00000004297	BRCA1-A complex subunit Abraxas.	BRISC and BRCA1 A complex member 1.	0.997
ABRAXAS1	Brcc3	ENSFDAP00000003313	ENSFDAP00000004359	BRCA1-A complex subunit Abraxas.	Lys-63-specific deubiquitinase BRCC36.	0.990
ABRAXAS1	ENSFDAP00000001970	ENSFDAP00000003313	ENSFDAP00000001970	BRCA1-A complex subunit Abraxas.	annotation not available	0.986
ABRAXAS1	H920_04415	ENSFDAP00000003313	ENSFDAP00000019629	BRCA1-A complex subunit Abraxas.	BRCA1-A complex subunit RAP80.	0.996
BABAM2	ABRAXAS1	ENSFDAP00000013136	ENSFDAP00000003313	BRISC and BRCA1 A complex member 2.	BRCA1-A complex subunit Abraxas.	0.995
BABAM2	BARD1	ENSFDAP00000013136	ENSFDAP00000018225	BRISC and BRCA1 A complex member 2.	BRCA1-associated RING domain protein 1.	0.907
BABAM2	BRCA1	ENSFDAP00000013136	ENSFDAP00000004478	BRISC and BRCA1 A complex member 2.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.946
BABAM2	Babam1	ENSFDAP00000013136	ENSFDAP00000004297	BRISC and BRCA1 A complex member 2.	BRISC and BRCA1 A complex member 1.	0.999
BABAM2	Brcc3	ENSFDAP00000013136	ENSFDAP00000004359	BRISC and BRCA1 A complex member 2.	Lys-63-specific deubiquitinase BRCC36.	0.986
BABAM2	ENSFDAP00000001970	ENSFDAP00000013136	ENSFDAP00000001970	BRISC and BRCA1 A complex member 2.	annotation not available	0.986
BABAM2	H920_04415	ENSFDAP00000013136	ENSFDAP00000019629	BRISC and BRCA1 A complex member 2.	BRCA1-A complex subunit RAP80.	0.996
BARD1	ABRAXAS1	ENSFDAP00000018225	ENSFDAP00000003313	BRCA1-associated RING domain protein 1.	BRCA1-A complex subunit Abraxas.	0.994
BARD1	BABAM2	ENSFDAP00000018225	ENSFDAP00000013136	BRCA1-associated RING domain protein 1.	BRISC and BRCA1 A complex member 2.	0.907
BARD1	BRCA1	ENSFDAP00000018225	ENSFDAP00000004478	BRCA1-associated RING domain protein 1.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.998
BARD1	Babam1	ENSFDAP00000018225	ENSFDAP00000004297	BRCA1-associated RING domain protein 1.	BRISC and BRCA1 A complex member 1.	0.989
BARD1	Brcc3	ENSFDAP00000018225	ENSFDAP00000004359	BRCA1-associated RING domain protein 1.	Lys-63-specific deubiquitinase BRCC36.	0.895
BARD1	ENSFDAP00000001970	ENSFDAP00000018225	ENSFDAP00000001970	BRCA1-associated RING domain protein 1.	annotation not available	0.895