STRINGSTRING
FBXW7 FBXW7 UBE2E2 UBE2E2 H920_09142 H920_09142 H920_00962 H920_00962 UBE2E3 UBE2E3 ENSFDAP00000017776 ENSFDAP00000017776 RNF126 RNF126 TRAF2 TRAF2 PELI1 PELI1 TRAF3 TRAF3 TRIM27 TRIM27 PELI3 PELI3 RNF115 RNF115 PRPF19 PRPF19 RNF168 RNF168 WWP2 WWP2 ENSFDAP00000020777 ENSFDAP00000020777 TRIM21 TRIM21 TRAF3IP2 TRAF3IP2 UBE2V2 UBE2V2 RNF5 RNF5 Bfar Bfar TRAF1 TRAF1 FBXW9 FBXW9 Arih2 Arih2 H920_12355 H920_12355 RNF8 RNF8 MAGEL2 MAGEL2 HECTD1 HECTD1 TRAF5 TRAF5 UBE2O UBE2O RNF213 RNF213 UBE2S UBE2S RNF135 RNF135 TRIM56 TRIM56 STUB1 STUB1 ENSFDAP00000006648 ENSFDAP00000006648 UBE2T UBE2T RNF152 RNF152 RNF4 RNF4 TRAF6 TRAF6 NEDD4 NEDD4 H920_07462 H920_07462 UBE2G1 UBE2G1 ENSFDAP00000014465 ENSFDAP00000014465 UBE2V1 UBE2V1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBXW7F-box/WD repeat-containing protein 7. (708 aa)
UBE2E2Ubiquitin-conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
H920_09142E3 ubiquitin-protein ligase ZFP91. (491 aa)
H920_00962Tripartite motif-containing protein 5. (476 aa)
UBE2E3Ubiquitin-conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
ENSFDAP00000017776annotation not available (72 aa)
RNF126RING finger protein 126. (288 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
TRIM27Tripartite motif containing 27. (461 aa)
PELI3Pellino E3 ubiquitin protein ligase family member 3. (445 aa)
RNF115E3 ubiquitin-protein ligase RNF115. (306 aa)
PRPF19Pre-mRNA-processing factor 19. (440 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (559 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
ENSFDAP00000020777annotation not available (90 aa)
TRIM21E3 ubiquitin-protein ligase TRIM21. (467 aa)
TRAF3IP2Adapter protein CIKS. (546 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
RNF5E3 ubiquitin-protein ligase RNF5. (180 aa)
BfarBifunctional apoptosis regulator. (448 aa)
TRAF1TNF receptor-associated factor. (415 aa)
FBXW9F-box/WD repeat-containing protein 9. (444 aa)
Arih2RBR-type E3 ubiquitin transferase. (491 aa)
H920_12355Bifunctional polynucleotide phosphatase/kinase. (173 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (449 aa)
MAGEL2MAGE-like protein 2. (1017 aa)
HECTD1E3 ubiquitin-protein ligase HECTD1. (2563 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
UBE2OUbiquitin-conjugating enzyme E2 O. (1139 aa)
RNF213RING finger protein 213. (5080 aa)
UBE2SUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (212 aa)
RNF135Ring finger protein 135. (389 aa)
TRIM56E3 ubiquitin-protein ligase TRIM56. (733 aa)
STUB1STIP1 homology and U box-containing protein 1. (250 aa)
ENSFDAP00000006648annotation not available (129 aa)
UBE2TUbiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (205 aa)
RNF152E3 ubiquitin-protein ligase RNF152. (203 aa)
RNF4E3 ubiquitin ligase RNF4. (193 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
NEDD4E3 ubiquitin-protein ligase. (837 aa)
H920_07462Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
UBE2G1Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
ENSFDAP00000014465annotation not available (393 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (175 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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