STRINGSTRING
GIT1 GIT1 MED1 MED1 ENSFDAP00000010230 ENSFDAP00000010230 DAB2IP DAB2IP SNAI2 SNAI2 ERBB4 ERBB4 ZPR1 ZPR1 INPP5K INPP5K CFLAR CFLAR IQGAP1 IQGAP1 H920_09344 H920_09344 Ppp1r9b Ppp1r9b DUSP22 DUSP22 ZFP36L1 ZFP36L1 GAREM2 GAREM2 NCL NCL LOC104873657 LOC104873657 AKT1 AKT1 Becn1 Becn1 PDPK1 PDPK1 GAREM1 GAREM1 SOX9 SOX9 Mcm7 Mcm7 H920_17227 H920_17227 PTPN11 PTPN11 PDE8A PDE8A Tpr Tpr EGFR EGFR SYAP1 SYAP1 PLCG1 PLCG1 MAPK1 MAPK1 ZFP36 ZFP36 ARPC2 ARPC2 MAPK3 MAPK3 IREB2 IREB2 VIL1 VIL1 MARS1 MARS1 DAB2 DAB2 ERRFI1 ERRFI1 BAG4 BAG4 COL1A1 COL1A1 PAX2 PAX2 RASA1 RASA1 BAIAP2 BAIAP2 ERBB2 ERBB2 Dusp3 Dusp3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GIT1ARF GTPase-activating protein GIT1. (770 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1568 aa)
ENSFDAP00000010230annotation not available (709 aa)
DAB2IPDisabled like protein 2-interacting protein. (1161 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
ERBB4Receptor tyrosine-protein kinase erbB-4. (1280 aa)
ZPR1Zinc finger protein ZPR1. (458 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (467 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (435 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1638 aa)
H920_09344Nucleoprotein TPR. (420 aa)
Ppp1r9bNeurabin-2. (365 aa)
DUSP22Dual specificity protein phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (197 aa)
ZFP36L1Zinc finger protein 36, C3H1 type-like 1. (338 aa)
GAREM2Protein FAM59B. (535 aa)
NCLNucleolin. (708 aa)
LOC104873657mucin-5AC. (2600 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Becn1Beclin-1. (448 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (558 aa)
GAREM1Protein FAM59A. (833 aa)
SOX9Transcription factor Sox-9-B. (430 aa)
Mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
H920_17227Beclin-1. (445 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (600 aa)
PDE8APhosphodiesterase. (772 aa)
TprNucleoprotein TPR. (2370 aa)
EGFRReceptor protein-tyrosine kinase. (1168 aa)
SYAP1Synapse-associated protein 1. (351 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
MAPK1Mitogen-activated protein kinase. (320 aa)
ZFP36Tristetraprolin. (315 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
IREB2Iron-responsive element-binding protein 2; Belongs to the aconitase/IPM isomerase family. (963 aa)
VIL1Villin-1. (827 aa)
MARS1Methionyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (883 aa)
DAB2Disabled like protein 2. (769 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (461 aa)
BAG4BAG family molecular chaperone regulator 4. (441 aa)
COL1A1Collagen alpha-1(I) chain. (1453 aa)
PAX2Paired box protein Pax-2. (359 aa)
RASA1Ras GTPase-activating protein 1. (893 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2. (536 aa)
ERBB2Receptor protein-tyrosine kinase. (1212 aa)
Dusp3Dual specificity phosphatase 3. (117 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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