42 items (Fukomys damarensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RREB1	Ras-responsive element-binding protein 1. (1522 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2551 aa)
	HRG	Histidine-rich glycoprotein. (521 aa)
	SERPINE1	Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
	PTK2	Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1083 aa)
	FERMT1	Fermitin family like protein 1. (677 aa)
	ENPP4	Ectonucleotide pyrophosphatase/phosphodiesterase family member 4. (456 aa)
	HPSE	Heparanase. (522 aa)
	DUOX2	Dual oxidase 2. (1330 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (803 aa)
	CLEC7A	C-type lectin domain family 7 member A. (201 aa)
	F2R	Proteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (403 aa)
	ANO6	Anoctamin. (910 aa)
	PLG	Plasminogen. (837 aa)
	ARFGEF1	Brefeldin A-inhibited guanine nucleotide-exchange protein 1. (1848 aa)
	APOH	Beta-2-glycoprotein 1. (345 aa)
	DUOX1	Dual oxidase 1. (1329 aa)
	Xbp1	X-box-binding protein 1. (337 aa)
	CXCR4	C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	SERPINF2	Alpha-2-antiplasmin; Belongs to the serpin family. (427 aa)
	VEGFB	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (168 aa)
	PRKCE	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (736 aa)
	CD36	Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
	DMTN	Dematin. (377 aa)
	ANXA1	Annexin A1. (346 aa)
	SMOC2	SPARC-related modular calcium-binding protein 2. (418 aa)
	NFE2L2	Nuclear factor erythroid 2-related factor 2. (602 aa)
	KANK1	KN motif and ankyrin repeat domain-containing protein 1. (1349 aa)
	F12	Coagulation factor XII. (606 aa)
	F2	Coagulation factor II, thrombin. (565 aa)
	CLDN4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (201 aa)
	MYLK	Myosin light chain kinase, smooth muscle. (1926 aa)
	FERMT2	Fermitin family like protein 2. (716 aa)
	PRDX2	Peroxiredoxin-2. (198 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	CPB2	Carboxypeptidase B2. (423 aa)
	CCN4	WNT1-inducible-signaling pathway protein 1. (287 aa)
	ST3GAL4	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (333 aa)
	DDR2	Discoidin domain-containing receptor 2. (882 aa)
	THBS1	Thrombospondin-1. (1181 aa)
	PTGER4	Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (492 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	APOH	ENSFDAP00000006349	ENSFDAP00000002811	Annexin A1.	Beta-2-glycoprotein 1.	0.542
ANXA1	F12	ENSFDAP00000006349	ENSFDAP00000007895	Annexin A1.	Coagulation factor XII.	0.464
ANXA1	F2	ENSFDAP00000006349	ENSFDAP00000009635	Annexin A1.	Coagulation factor II, thrombin.	0.505
ANXA1	PLG	ENSFDAP00000006349	ENSFDAP00000020863	Annexin A1.	Plasminogen.	0.790
ANXA1	SERPINF2	ENSFDAP00000006349	ENSFDAP00000003288	Annexin A1.	Alpha-2-antiplasmin; Belongs to the serpin family.	0.421
APOH	ANXA1	ENSFDAP00000002811	ENSFDAP00000006349	Beta-2-glycoprotein 1.	Annexin A1.	0.542
APOH	CPB2	ENSFDAP00000002811	ENSFDAP00000010941	Beta-2-glycoprotein 1.	Carboxypeptidase B2.	0.400
APOH	F12	ENSFDAP00000002811	ENSFDAP00000007895	Beta-2-glycoprotein 1.	Coagulation factor XII.	0.689
APOH	F2	ENSFDAP00000002811	ENSFDAP00000009635	Beta-2-glycoprotein 1.	Coagulation factor II, thrombin.	0.936
APOH	HRG	ENSFDAP00000002811	ENSFDAP00000016909	Beta-2-glycoprotein 1.	Histidine-rich glycoprotein.	0.850
APOH	PLG	ENSFDAP00000002811	ENSFDAP00000020863	Beta-2-glycoprotein 1.	Plasminogen.	0.894
APOH	SERPINF2	ENSFDAP00000002811	ENSFDAP00000003288	Beta-2-glycoprotein 1.	Alpha-2-antiplasmin; Belongs to the serpin family.	0.806
ARFGEF1	MTOR	ENSFDAP00000002511	ENSFDAP00000016649	Brefeldin A-inhibited guanine nucleotide-exchange protein 1.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.416
CD36	CLEC7A	ENSFDAP00000006136	ENSFDAP00000022261	Platelet glycoprotein 4; Belongs to the CD36 family.	C-type lectin domain family 7 member A.	0.431
CD36	ITGB1	ENSFDAP00000006136	ENSFDAP00000022103	Platelet glycoprotein 4; Belongs to the CD36 family.	Integrin beta; Belongs to the integrin beta chain family.	0.794
CD36	THBS1	ENSFDAP00000006136	ENSFDAP00000014077	Platelet glycoprotein 4; Belongs to the CD36 family.	Thrombospondin-1.	0.971
CLDN1	CLDN4	ENSFDAP00000022029	ENSFDAP00000009763	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.920
CLDN4	CLDN1	ENSFDAP00000009763	ENSFDAP00000022029	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.920
CLEC7A	CD36	ENSFDAP00000022261	ENSFDAP00000006136	C-type lectin domain family 7 member A.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.431
CLEC7A	F12	ENSFDAP00000022261	ENSFDAP00000007895	C-type lectin domain family 7 member A.	Coagulation factor XII.	0.568