STRINGSTRING
Acsl6 Acsl6 AKT2 AKT2 EPRS1 EPRS1 ARV1 ARV1 PLTP PLTP Nus1 Nus1 EEPD1 EEPD1 FIS1 FIS1 FURIN FURIN PLIN3 PLIN3 ZDHHC8 ZDHHC8 ABCG8 ABCG8 EHD1 EHD1 PLA2R1 PLA2R1 APOE APOE HBP1 HBP1 ENSFDAP00000021037 ENSFDAP00000021037 Naxe Naxe LIPG LIPG ABCA3 ABCA3 LOC104872673 LOC104872673 VSTM2B VSTM2B ASXL2 ASXL2 CAV1 CAV1 H920_04941 H920_04941 GALR1 GALR1 PTPN2 PTPN2 ADIPOQ ADIPOQ APOA2 APOA2 APOA4 APOA4 Apoc1 Apoc1 AGT AGT ACSL5 ACSL5 NR1H2 NR1H2 TRIAP1 TRIAP1 P2RX7 P2RX7 APOA1 APOA1 LOC104848797 LOC104848797 H920_05631 H920_05631 Il1b Il1b SIRT1 SIRT1 TNFSF11 TNFSF11 ABCA2 ABCA2 H920_11509 H920_11509 PPARA PPARA DAB2 DAB2 ABCG5 ABCG5 OSBPL8 OSBPL8 LRAT LRAT PPARD PPARD H920_06673 H920_06673 AGTR2 AGTR2 PLIN2 PLIN2 PPARG PPARG CRY2 CRY2 Cry1 Cry1 NFKBIA NFKBIA Itgb3 Itgb3 ABCA7 ABCA7 ABCG4 ABCG4 C3 C3 PLA2G4A PLA2G4A Anxa2 Anxa2 PLA2G3 PLA2G3 OSBPL6 OSBPL6 ABCA5 ABCA5 ABCG1 ABCG1 DGAT1 DGAT1 LOC104860587 LOC104860587 OSBPL11 OSBPL11 THBS1 THBS1 REPIN1 REPIN1 Pla2g10 Pla2g10 PNPLA2 PNPLA2 Tmem30a Tmem30a FITM1 FITM1 Faslg Faslg ENPP7 ENPP7 SYK SYK NRG1 NRG1 ATP8A1 ATP8A1 SHH SHH P2RY2 P2RY2 C1QTNF6 C1QTNF6 TSPO TSPO CYP8B1 CYP8B1 MAPK9 MAPK9 APOA5 APOA5 TREM2 TREM2 ABCB4 ABCB4 CRH CRH LDLRAP1 LDLRAP1 ENSFDAP00000010317 ENSFDAP00000010317 RETN RETN LRP1 LRP1 ACACB ACACB ENSFDAP00000009652 ENSFDAP00000009652 LPCAT3 LPCAT3 GAL GAL KDM5B KDM5B LOC104860586 LOC104860586 BMP6 BMP6 APOC2 APOC2 NUCB2 NUCB2 Igfbp3 Igfbp3 LOC104872961 LOC104872961 MFN2 MFN2 ABCA8 ABCA8 SEC24A SEC24A ABCA1 ABCA1 MAP2K6 MAP2K6 TTC39B TTC39B ITGAV ITGAV ZC3H12A ZC3H12A ABHD5 ABHD5 ATP5PF ATP5PF PRKCD PRKCD GPS2 GPS2 LOC104850496 LOC104850496 DENND5B DENND5B NR1H3 NR1H3 ABCA12 ABCA12 CD36 CD36 TTC39A TTC39A C1QTNF1 C1QTNF1 APOB APOB TMF1 TMF1 LEP LEP SURF4 SURF4 LPL LPL Prap1 Prap1 PRELID1 PRELID1 SREBF2 SREBF2 AKT1 AKT1 PTCH1 PTCH1 COMMD1 COMMD1 FITM2 FITM2 REN REN GDF9 GDF9 CYP19A1 CYP19A1 SCARB1 SCARB1 HILPDA HILPDA SPP1 SPP1 PLA2G6 PLA2G6 LOC104871533 LOC104871533 IRAK1 IRAK1 PON1 PON1 TNFRSF11A TNFRSF11A Ikbke Ikbke PCSK9 PCSK9 LAMTOR1 LAMTOR1 SAR1B SAR1B PTPN11 PTPN11 EGF EGF AVPR1B AVPR1B Dbi Dbi SCP2 SCP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Acsl6Long-chain-fatty-acid--CoA ligase 6. (722 aa)
AKT2RAC-beta serine/threonine-protein kinase. (481 aa)
EPRS1Bifunctional aminoacyl-tRNA synthetase. (1495 aa)
ARV1Protein ARV1. (250 aa)
PLTPPhospholipid transfer protein. (494 aa)
Nus1Nogo-B receptor. (154 aa)
EEPD1Endonuclease/exonuclease/phosphatase family domain-containing protein 1. (569 aa)
FIS1Mitochondrial fission 1 protein. (152 aa)
FURINFurin; Belongs to the peptidase S8 family. (796 aa)
PLIN3Perilipin-3. (348 aa)
ZDHHC8Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (727 aa)
ABCG8ATP-binding cassette sub-family G member 8. (677 aa)
EHD1EH domain-containing protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (534 aa)
PLA2R1Secretory phospholipase A2 receptor. (1462 aa)
APOEApolipoprotein E. (228 aa)
HBP1HMG box-containing protein 1. (524 aa)
ENSFDAP00000021037annotation not available (505 aa)
NaxeApolipoprotein A-I-binding protein. (128 aa)
LIPGEndothelial lipase. (500 aa)
ABCA3ATP-binding cassette sub-family A member 3. (1704 aa)
LOC104872673Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (545 aa)
VSTM2BV-set and transmembrane domain containing 2B. (178 aa)
ASXL2Putative Polycomb group protein ASXL2. (1406 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
H920_04941Apolipoprotein C-IV. (97 aa)
GALR1Galanin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (389 aa)
ADIPOQAdiponectin. (246 aa)
APOA2Apolipoprotein A-II. (101 aa)
APOA4Apolipoprotein A-IV. (399 aa)
Apoc1Apolipoprotein C-I. (68 aa)
AGTAngiotensinogen; Belongs to the serpin family. (478 aa)
ACSL5Long-chain-fatty-acid--CoA ligase 5. (682 aa)
NR1H2Oxysterols receptor LXR-beta. (368 aa)
TRIAP1TP53-regulated inhibitor of apoptosis 1. (76 aa)
P2RX7p2X purinoceptor 7. (583 aa)
APOA1Apolipoprotein A1. (264 aa)
LOC104848797Tetratricopeptide repeat protein 39B. (605 aa)
H920_05631V-set and transmembrane domain-containing protein 2A. (159 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
SIRT1NAD-dependent deacetylase sirtuin-1. (603 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (287 aa)
ABCA2ATP-binding cassette sub-family A member 2. (2405 aa)
H920_11509Cell cycle control protein; Belongs to the CDC50/LEM3 family. (344 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
DAB2Disabled like protein 2. (769 aa)
ABCG5ATP-binding cassette sub-family G member 5. (639 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (890 aa)
LRATLecithin retinol acyltransferase. (236 aa)
PPARDPeroxisome proliferator-activated receptor delta. (440 aa)
H920_06673Prostaglandin E synthase. (80 aa)
AGTR2Angiotensin II receptor type 2. (363 aa)
PLIN2Perilipin; Belongs to the perilipin family. (337 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
CRY2Cryptochrome-2. (545 aa)
Cry1Cryptochrome-1. (537 aa)
NFKBIANF-kappa-B inhibitor alpha. (224 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (761 aa)
ABCA7ATP-binding cassette sub-family A member 7. (1989 aa)
ABCG4ATP-binding cassette sub-family G member 4. (646 aa)
C3Complement C3. (1489 aa)
PLA2G4APhospholipase A2. (749 aa)
Anxa2Annexin. (339 aa)
PLA2G3Group 3 secretory phospholipase A2. (508 aa)
OSBPL6Oxysterol-binding protein-related protein 6. (967 aa)
ABCA5ATP-binding cassette sub-family A member 5. (1638 aa)
ABCG1ATP-binding cassette sub-family G member 1. (618 aa)
DGAT1O-acyltransferase. (459 aa)
LOC104860587Liver carboxylesterase 22. (314 aa)
OSBPL11Oxysterol binding protein like 11. (714 aa)
THBS1Thrombospondin-1. (1181 aa)
REPIN1Replication initiator 1. (588 aa)
Pla2g10Phospholipase A(2). (215 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2. (429 aa)
Tmem30aCell cycle control protein 50A. (353 aa)
FITM1Fat storage-inducing transmembrane protein 1. (292 aa)
FaslgTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (69 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase family member 7. (429 aa)
SYKTyrosine-protein kinase. (629 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform. (699 aa)
ATP8A1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1155 aa)
SHHSonic hedgehog protein. (244 aa)
P2RY2p2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
C1QTNF6C1q and TNF related 6. (320 aa)
TSPOTranslocator protein. (168 aa)
CYP8B17-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (502 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
APOA5Apolipoprotein A-V. (367 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (231 aa)
ABCB4Multidrug resistance protein 3. (1253 aa)
CRHCorticoliberin. (194 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (278 aa)
ENSFDAP00000010317annotation not available (274 aa)
RETNResistin. (111 aa)
LRP1Prolow-density lipoprotein receptor-related protein 1. (4419 aa)
ACACBAcetyl-CoA carboxylase 2. (2409 aa)
ENSFDAP00000009652annotation not available (156 aa)
LPCAT3Lysophospholipid acyltransferase 5; Belongs to the membrane-bound acyltransferase family. (422 aa)
GALGalanin peptide. (94 aa)
KDM5BLysine-specific demethylase 5B. (1424 aa)
LOC104860586Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
BMP6Bone morphogenetic protein 6. (319 aa)
APOC2Apolipoprotein C-II. (101 aa)
NUCB2Nucleobindin-2. (420 aa)
Igfbp3Insulin-like growth factor-binding protein 3. (170 aa)
LOC104872961Allergen Fel d 4; Belongs to the calycin superfamily. Lipocalin family. (283 aa)
MFN2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (762 aa)
ABCA8ATP-binding cassette sub-family A member 8-A. (1618 aa)
SEC24AProtein transport protein Sec24A. (1059 aa)
ABCA1ATP-binding cassette sub-family A member 1. (2119 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (335 aa)
TTC39BTetratricopeptide repeat protein 39B. (604 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (996 aa)
ZC3H12ARibonuclease ZC3H12A. (595 aa)
ABHD51-acylglycerol-3-phosphate O-acyltransferase ABHD5. (333 aa)
ATP5PFATP synthase peripheral stalk subunit F6. (108 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
GPS2G protein pathway suppressor 2. (336 aa)
LOC104850496Cell cycle control protein 50A-like. (364 aa)
DENND5BDENN domain-containing protein 5B. (1195 aa)
NR1H3Oxysterols receptor LXR-alpha. (443 aa)
ABCA12ATP-binding cassette sub-family A member 12. (2599 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
TTC39ATetratricopeptide repeat protein 39A. (578 aa)
C1QTNF1Complement C1q tumor necrosis factor-related protein 1. (281 aa)
APOBApolipoprotein B-100. (4381 aa)
TMF1TATA element modulatory factor. (1093 aa)
LEPLeptin. (167 aa)
SURF4Uncharacterized protein. (253 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
Prap1Proline-rich acidic protein 1. (148 aa)
PRELID1PRELI domain-containing protein 1, mitochondrial. (219 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1120 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PTCH1Protein patched like protein 1. (1437 aa)
COMMD1COMM domain-containing protein 1. (188 aa)
FITM2Fat storage-inducing transmembrane protein 2. (261 aa)
RENRenin; Belongs to the peptidase A1 family. (398 aa)
GDF9Growth differentiation factor 9. (433 aa)
CYP19A1Cytochrome P450 19A1. (499 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (502 aa)
HILPDAHypoxia-inducible gene 2 protein. (64 aa)
SPP1Osteopontin. (344 aa)
PLA2G685 kDa calcium-independent phospholipase A2. (806 aa)
LOC104871533Corticotropin-releasing factor receptor 1; Belongs to the G-protein coupled receptor 2 family. (404 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (453 aa)
PON1Serum paraoxonase/arylesterase 1. (354 aa)
TNFRSF11ATNF receptor superfamily member 11a. (544 aa)
IkbkeInhibitor of nuclear factor kappa-B kinase subunit epsilon. (130 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (567 aa)
LAMTOR1Ragulator complex protein LAMTOR1. (161 aa)
SAR1BGTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (600 aa)
EGFPro-epidermal growth factor. (1155 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (434 aa)
DbiAcyl-CoA-binding protein. (87 aa)
SCP2Non-specific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
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