(13 nodes) SMAD-like domain superfamily network (Fukomys damarensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IRF4	Interferon regulatory factor 4. (379 aa)
	SMAD5	Mothers against decapentaplegic homolog. (465 aa)
	SMAD7	Mothers against decapentaplegic homolog. (229 aa)
	Rnf31	RING finger protein 31. (1069 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	IRF7	Interferon regulatory factor 7. (430 aa)
	IRF3	Interferon regulatory factor 3. (428 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	IRF6	Interferon regulatory factor 6. (462 aa)
	IRF8	Interferon regulatory factor 8. (426 aa)
	Smad9	Mothers against decapentaplegic homolog. (430 aa)
	SMAD3	Mothers against decapentaplegic homolog. (429 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)

Your Current Organism:

Fukomys damarensis

NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IRF3	IRF7	ENSFDAP00000017443	ENSFDAP00000016433	Interferon regulatory factor 3.	Interferon regulatory factor 7.	0.976
IRF3	SMAD1	ENSFDAP00000017443	ENSFDAP00000005398	Interferon regulatory factor 3.	Mothers against decapentaplegic homolog.	0.453
IRF3	SMAD2	ENSFDAP00000017443	ENSFDAP00000015181	Interferon regulatory factor 3.	Mothers against decapentaplegic homolog.	0.498
IRF3	SMAD3	ENSFDAP00000017443	ENSFDAP00000005300	Interferon regulatory factor 3.	Mothers against decapentaplegic homolog.	0.532
IRF3	SMAD4	ENSFDAP00000017443	ENSFDAP00000020857	Interferon regulatory factor 3.	Mothers against decapentaplegic homolog.	0.447
IRF3	SMAD5	ENSFDAP00000017443	ENSFDAP00000008621	Interferon regulatory factor 3.	Mothers against decapentaplegic homolog.	0.453
IRF3	SMAD7	ENSFDAP00000017443	ENSFDAP00000009760	Interferon regulatory factor 3.	Mothers against decapentaplegic homolog.	0.447
IRF3	Smad9	ENSFDAP00000017443	ENSFDAP00000004402	Interferon regulatory factor 3.	Mothers against decapentaplegic homolog.	0.453
IRF4	SMAD1	ENSFDAP00000008536	ENSFDAP00000005398	Interferon regulatory factor 4.	Mothers against decapentaplegic homolog.	0.447
IRF4	SMAD2	ENSFDAP00000008536	ENSFDAP00000015181	Interferon regulatory factor 4.	Mothers against decapentaplegic homolog.	0.554
IRF4	SMAD3	ENSFDAP00000008536	ENSFDAP00000005300	Interferon regulatory factor 4.	Mothers against decapentaplegic homolog.	0.491
IRF4	SMAD4	ENSFDAP00000008536	ENSFDAP00000020857	Interferon regulatory factor 4.	Mothers against decapentaplegic homolog.	0.447
IRF4	SMAD5	ENSFDAP00000008536	ENSFDAP00000008621	Interferon regulatory factor 4.	Mothers against decapentaplegic homolog.	0.447
IRF4	SMAD7	ENSFDAP00000008536	ENSFDAP00000009760	Interferon regulatory factor 4.	Mothers against decapentaplegic homolog.	0.447
IRF4	Smad9	ENSFDAP00000008536	ENSFDAP00000004402	Interferon regulatory factor 4.	Mothers against decapentaplegic homolog.	0.447
IRF6	SMAD1	ENSFDAP00000000463	ENSFDAP00000005398	Interferon regulatory factor 6.	Mothers against decapentaplegic homolog.	0.447
IRF6	SMAD2	ENSFDAP00000000463	ENSFDAP00000015181	Interferon regulatory factor 6.	Mothers against decapentaplegic homolog.	0.451
IRF6	SMAD3	ENSFDAP00000000463	ENSFDAP00000005300	Interferon regulatory factor 6.	Mothers against decapentaplegic homolog.	0.451
IRF6	SMAD4	ENSFDAP00000000463	ENSFDAP00000020857	Interferon regulatory factor 6.	Mothers against decapentaplegic homolog.	0.447
IRF6	SMAD5	ENSFDAP00000000463	ENSFDAP00000008621	Interferon regulatory factor 6.	Mothers against decapentaplegic homolog.	0.447